Basis: Trailing twelve months (TTM net income over TTM revenue). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the net profit margin high or low?
The net profit margin of -219.50% is 31% above its 5-year average of -318.33%, near the high end of its 5-year range (-1345.03%–-10.39%).
32.19% above its 12-month average of -323.71%.
Reported quarterly profit margin; no daily interpolation. Q2 FY2026 (2026-06-30): -220.98%.
NET PROFIT MARGIN
-219.50%
NET PROFIT MARGIN AVG TTM
-323.71%
NET PROFIT MARGIN AVG 3Y
-326.23%
NET PROFIT MARGIN AVG 5Y
-318.33%
NET PROFIT MARGIN AVG 10Y
-460.72%
NET PROFIT MARGIN AVG 15Y
-399.21%
NET PROFIT MARGIN AVG 20Y
-381.85%
CURRENT VS TTM AVG
+32.19%
CURRENT VS 3Y AVG
+32.72%
CURRENT VS 5Y AVG
+31.05%
CURRENT VS 10Y AVG
+52.36%
CURRENT VS 15Y AVG
+45.02%
CURRENT VS 20Y AVG
+42.52%
SECTOR MEDIAN · HEALTHCARE
0.00%
median of 517 covered companies
CURRENT VS SECTOR MEDIAN
N/A
vs the sector median at left
Dyadic International, Inc.
Market Cap
$17.13M
Net Profit Margin
-219.50%
TTM Avg
-323.71%
3Y Avg
-326.23%
5Y Avg
-318.33%
Market Cap
$17.07M
Net Profit Margin
-755.13%
TTM Avg
-243.50%
3Y Avg
-516.28%
5Y Avg
-344.84%
Market Cap
$16.57M
Net Profit Margin
-106.58%
TTM Avg
-228.29%
3Y Avg
-394.31%
5Y Avg
-410.59%
Market Cap
$16.37M
Net Profit Margin
0.00%
TTM Avg
-6850.00%
3Y Avg
-4251.62%
5Y Avg
-4766.26%
Market Cap
$15.91M
Net Profit Margin
-3575.07%
TTM Avg
-1754.85%
3Y Avg
-877.42%
5Y Avg
-584.95%
Market Cap
$18.58M
Net Profit Margin
-33.08%
TTM Avg
-29.53%
3Y Avg
-30.32%
5Y Avg
-22.32%
Market Cap
$15.57M
Net Profit Margin
-153.28%
TTM Avg
-93.42%
3Y Avg
-97.51%
5Y Avg
-105.13%
Market Cap
$18.87M
Net Profit Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
Market Cap
$15.35M
Net Profit Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
-2405.08%
| NAME | MARKET CAP | NET PROFIT MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Dyadic International, Inc. (DYAI) | $17.13M | -219.50% | -323.71% | -326.23% | -318.33% |
| Lipocine Inc. (LPCN)vs › | $17.07M | -755.13% | -243.50% | -516.28% | -344.84% |
| Bionano Genomics, Inc. (BNGO)vs › | $16.57M | -106.58% | -228.29% | -394.31% | -410.59% |
| BioCardia, Inc. (BCDA)vs › | $16.37M | 0.00% | -6850.00% | -4251.62% | -4766.26% |
| Allarity Therapeutics, Inc. (ALLR)vs › | $15.91M | -3575.07% | -1754.85% | -877.42% | -584.95% |
| Cosmos Health Inc. (COSM)vs › | $18.58M | -33.08% | -29.53% | -30.32% | -22.32% |
| Karyopharm Therapeutics Inc. (KPTI)vs › | $15.57M | -153.28% | -93.42% | -97.51% | -105.13% |
| Estrella Immunopharma, Inc. (ESLA)vs › | $18.87M | 0.00% | 0.00% | 0.00% | 0.00% |
| Pasithea Therapeutics Corp. (KTTA)vs › | $15.35M | 0.00% | 0.00% | 0.00% | -2405.08% |
| Cocrystal Pharma, Inc. (COCP)vs › | $15.33M | -3011.52% | 0.00% | 0.00% | -79.84% |
Operating Margin
-579.9%
Net Profit Margin
-219.5%
Net Profit Margin = Net Income / Revenue
Net profit margin is the percentage of revenue that becomes net income after all expenses, taxes, and interest.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | NET PROFIT MARGIN |
|---|---|
| 2026-06-30 | -220.98% |
| 2026-03-31 | -175.95% |
| 2025-12-31 | -664.89% |
| 2025-09-30 | -169.67% |
| 2025-06-30 | -387.05% |
| 2025-03-31 | -1107.36% |
| 2024-12-31 | -189.74% |
| 2024-09-30 | -10.39% |
| 2024-06-30 | -529.99% |
| 2024-03-31 | -600.57% |
| 2023-12-31 | -301.78% |
| 2023-09-30 | -406.55% |
| 2023-06-30 | -257.17% |
| 2023-03-31 | -97.79% |
| 2022-12-31 | -288.60% |
| 2022-09-30 | -205.68% |
| 2022-06-30 | -499.28% |
| 2022-03-31 | -384.26% |
| 2021-12-31 | -1345.03% |
| 2021-09-30 | -247.54% |
| 2021-06-30 | -410.44% |
| 2021-03-31 | -715.48% |
| 2020-12-31 | -566.67% |
| 2020-09-30 | -600.32% |
| 2020-06-30 | -505.74% |
| 2020-03-31 | -702.07% |
| 2019-12-31 | -401.35% |
| 2019-09-30 | -373.68% |
| 2019-06-30 | -689.68% |
| 2019-03-31 | -540.40% |
| 2018-12-31 | -74.59% |
| 2018-09-30 | -585.45% |
| 2018-06-30 | -989.94% |
| 2018-03-31 | -1108.50% |
| 2017-12-31 | -871.26% |
| 2017-09-30 | -555.90% |
| 2017-06-30 | -650.67% |
| 2017-03-31 | 1725.00% |
| 2016-12-31 | -419.95% |
| 2016-09-30 | 0.00% |
| 2016-06-30 | 3726.64% |
| 2016-03-31 | -1079.61% |
| 2015-12-31 | 215667.92% |
| 2015-09-30 | 894.78% |
| 2015-06-30 | -1638.12% |
| 2015-03-31 | -997.84% |
| 2014-12-31 | -13.44% |
| 2014-09-30 | 17.31% |
| 2014-06-30 | -54.83% |
| 2014-03-31 | -52.56% |
| 2013-12-31 | -13.34% |
| 2013-09-30 | -50.32% |
| 2013-06-30 | 46.92% |
| 2013-03-31 | -58.84% |
| 2012-12-31 | -53.37% |
| 2012-09-30 | -15.54% |
| 2012-06-30 | 50.59% |
| 2012-03-31 | -30.95% |
| 2006-12-31 | -94.14% |
| 2006-09-30 | -55.75% |
| 2006-06-30 | -75.72% |
| 2006-03-31 | -61.36% |
| 2005-12-31 | -64.22% |
| 2005-09-30 | -61.16% |
| 2005-06-30 | -57.48% |
| 2005-03-31 | -83.24% |
| 2004-12-31 | -35.64% |
| 2004-09-30 | 0.00% |
| 2004-06-30 | -65.93% |
| 2004-03-31 | -51.31% |
| 2003-12-31 | -15.75% |
| 2003-09-30 | 0.00% |
| 2003-06-30 | -121.14% |
| 2003-03-31 | -155.39% |
