Basis: Trailing twelve months (TTM). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the gross margin high or low?
The gross margin of -88.25% is 379% below its 5-year average of 31.66%, near the low end of its 5-year range (-88.25%–79.78%).
5062.47% below its 12-month average of 1.78%.
Reported quarterly gross margin; no daily interpolation. Q2 FY2026 (2026-06-30): -2.40%.
GROSS MARGIN
-88.25%
GROSS MARGIN AVG TTM
1.78%
GROSS MARGIN AVG 3Y
22.25%
GROSS MARGIN AVG 5Y
31.66%
GROSS MARGIN AVG 10Y
17.37%
GROSS MARGIN AVG 15Y
20.71%
GROSS MARGIN AVG 20Y
20.07%
CURRENT VS TTM AVG
-5062.47%
CURRENT VS 3Y AVG
-496.58%
CURRENT VS 5Y AVG
-378.73%
CURRENT VS 10Y AVG
-607.92%
CURRENT VS 15Y AVG
-526.15%
CURRENT VS 20Y AVG
-539.76%
SECTOR MEDIAN · HEALTHCARE
42.90%
median of 561 covered companies
CURRENT VS SECTOR MEDIAN
-305.71%
vs the sector median at left
Dyadic International, Inc.
Market Cap
$16.87M
Gross Margin
-88.25%
TTM Avg
1.78%
3Y Avg
22.25%
5Y Avg
31.66%
Market Cap
$16.74M
Gross Margin
21.95%
TTM Avg
11.59%
3Y Avg
17.76%
5Y Avg
20.87%
Market Cap
$17.19M
Gross Margin
-334.26%
TTM Avg
-117.13%
3Y Avg
-347.18%
5Y Avg
-222.70%
Market Cap
$16.43M
Gross Margin
0.00%
TTM Avg
-3731.89%
3Y Avg
-2384.22%
5Y Avg
-1567.12%
Market Cap
$17.76M
Gross Margin
0.00%
TTM Avg
-52.16%
3Y Avg
-139.89%
5Y Avg
-776.52%
Market Cap
$15.75M
Gross Margin
107.54%
TTM Avg
50.00%
3Y Avg
25.00%
5Y Avg
16.67%
Market Cap
$15.44M
Gross Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
-33.27%
Market Cap
$15.39M
Gross Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
-2.45%
Market Cap
$15.18M
Gross Margin
95.88%
TTM Avg
95.90%
3Y Avg
96.27%
5Y Avg
96.83%
| NAME | MARKET CAP | GROSS MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Dyadic International, Inc. (DYAI) | $16.87M | -88.25% | 1.78% | 22.25% | 31.66% |
| Bionano Genomics, Inc. (BNGO)vs › | $16.74M | 21.95% | 11.59% | 17.76% | 20.87% |
| Lipocine Inc. (LPCN)vs › | $17.19M | -334.26% | -117.13% | -347.18% | -222.70% |
| BioCardia, Inc. (BCDA)vs › | $16.43M | 0.00% | -3731.89% | -2384.22% | -1567.12% |
| Marker Therapeutics, Inc. (MRKR)vs › | $17.76M | 0.00% | -52.16% | -139.89% | -776.52% |
| Allarity Therapeutics, Inc. (ALLR)vs › | $15.75M | 107.54% | 50.00% | 25.00% | 16.67% |
| Cocrystal Pharma, Inc. (COCP)vs › | $15.44M | 0.00% | 0.00% | 0.00% | -33.27% |
| Pasithea Therapeutics Corp. (KTTA)vs › | $15.39M | 0.00% | 0.00% | 0.00% | -2.45% |
| Karyopharm Therapeutics Inc. (KPTI)vs › | $15.18M | 95.88% | 95.90% | 96.27% | 96.83% |
| Cosmos Health Inc. (COSM)vs › | $19.02M | 10.27% | 10.01% | 10.00% | 11.56% |
Gross Margin
-88.3%
(Revenue - COGS) / Revenue
Gross Margin = Gross Profit / Revenue
Gross margin is the percentage of revenue remaining after the cost of goods sold, reflecting core product profitability.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | GROSS MARGIN |
|---|---|
| 2026-06-30 | -2.40% |
| 2026-03-31 | 28.72% |
| 2025-12-31 | -63.17% |
| 2025-09-30 | 78.13% |
| 2025-06-30 | -32.40% |
| 2025-03-31 | -62.57% |
| 2024-12-31 | 56.84% |
| 2024-09-30 | 79.78% |
| 2024-06-30 | 21.75% |
| 2024-03-31 | 56.98% |
| 2023-12-31 | 49.00% |
| 2023-09-30 | 73.34% |
| 2023-06-30 | 5.28% |
| 2023-03-31 | 25.68% |
| 2022-12-31 | 5.28% |
| 2022-09-30 | 31.46% |
| 2022-06-30 | 37.57% |
| 2022-03-31 | 37.58% |
| 2021-12-31 | -5.85% |
| 2021-09-30 | 43.35% |
| 2021-06-30 | 11.48% |
| 2021-03-31 | 15.15% |
| 2020-12-31 | 26.12% |
| 2020-09-30 | 35.89% |
| 2020-06-30 | -19.07% |
| 2020-03-31 | 11.79% |
| 2019-12-31 | 1.94% |
| 2019-09-30 | 15.34% |
| 2019-06-30 | 17.56% |
| 2019-03-31 | 18.54% |
| 2018-12-31 | 26.05% |
| 2018-09-30 | 7.44% |
| 2018-06-30 | 19.95% |
| 2018-03-31 | 20.36% |
| 2017-12-31 | 11.88% |
| 2017-09-30 | 19.07% |
| 2017-06-30 | 3.67% |
| 2017-03-31 | 0.00% |
| 2016-12-31 | 15.01% |
| 2016-09-30 | 0.00% |
| 2016-06-30 | 8.49% |
| 2016-03-31 | 2.01% |
| 2015-12-31 | -6.26% |
| 2015-09-30 | 83.61% |
| 2015-06-30 | 23.38% |
| 2015-03-31 | 18.64% |
| 2014-12-31 | 35.02% |
| 2014-09-30 | 100.05% |
| 2014-06-30 | 33.92% |
| 2014-03-31 | 33.70% |
| 2013-12-31 | 25.66% |
| 2013-09-30 | 19.98% |
| 2013-06-30 | 72.65% |
| 2013-03-31 | 20.97% |
| 2012-12-31 | 23.28% |
| 2012-09-30 | 24.36% |
| 2012-06-30 | 76.26% |
| 2012-03-31 | 30.00% |
| 2006-12-31 | 22.61% |
| 2006-09-30 | 31.20% |
| 2006-06-30 | 27.12% |
| 2006-03-31 | 23.14% |
| 2005-12-31 | 16.85% |
| 2005-09-30 | 19.86% |
| 2005-06-30 | 19.49% |
| 2005-03-31 | 20.07% |
| 2004-12-31 | 100.00% |
| 2004-09-30 | 0.00% |
| 2004-06-30 | 2.88% |
| 2004-03-31 | 23.52% |
| 2003-12-31 | 100.00% |
| 2003-09-30 | 0.00% |
| 2003-06-30 | 21.19% |
| 2003-03-31 | 18.55% |
