Basis: Trailing twelve months (TTM). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the EBITDA margin high or low?
The EBITDA margin of -61.90% is 26% above its 5-year average of -83.97%, around the middle of its 5-year range (-224.15%–37.30%).
8.32% above its 12-month average of -67.52%.
Reported quarterly EBITDA margin; no daily interpolation. Q1 FY2026 (2026-03-31): -76.28%.
EBITDA MARGIN
-61.90%
EBITDA MARGIN AVG TTM
-67.52%
EBITDA MARGIN AVG 3Y
-79.26%
EBITDA MARGIN AVG 5Y
-83.97%
EBITDA MARGIN AVG 10Y
-138.33%
EBITDA MARGIN AVG 15Y
N/A
EBITDA MARGIN AVG 20Y
N/A
CURRENT VS TTM AVG
+8.32%
CURRENT VS 3Y AVG
+21.91%
CURRENT VS 5Y AVG
+26.28%
CURRENT VS 10Y AVG
+55.25%
CURRENT VS 15Y AVG
N/A
CURRENT VS 20Y AVG
N/A
Karyopharm Therapeutics Inc.
Market Cap
$15.07M
EBITDA Margin
-61.90%
TTM Avg
-67.52%
3Y Avg
-79.26%
5Y Avg
-83.97%
Market Cap
$15.25M
EBITDA Margin
-29916.57%
TTM Avg
-29916.57%
3Y Avg
-29916.57%
5Y Avg
-29916.57%
Market Cap
$15.30M
EBITDA Margin
-468.17%
TTM Avg
-602.06%
3Y Avg
-602.06%
5Y Avg
-23374.02%
Market Cap
$14.57M
EBITDA Margin
-23.39%
TTM Avg
-215.41%
3Y Avg
-426.39%
5Y Avg
-612.06%
Market Cap
$15.81M
EBITDA Margin
-14633.33%
TTM Avg
-7486.14%
3Y Avg
-4543.27%
5Y Avg
-3157.51%
Market Cap
$13.90M
EBITDA Margin
N/A
TTM Avg
N/A
3Y Avg
N/A
5Y Avg
N/A
Market Cap
$16.08M
EBITDA Margin
-13679.31%
TTM Avg
-8051.39%
3Y Avg
-4553.85%
5Y Avg
-5076.49%
Market Cap
$13.97M
EBITDA Margin
-855.47%
TTM Avg
-475.86%
3Y Avg
-335.10%
5Y Avg
-307.83%
| NAME | MARKET CAP | EBITDA MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Karyopharm Therapeutics Inc. (KPTI) | $15.07M | -61.90% | -67.52% | -79.26% | -83.97% |
| Pasithea Therapeutics Corp. (KTTA)vs › | $15.25M | -29916.57% | -29916.57% | -29916.57% | -29916.57% |
| Cocrystal Pharma, Inc. (COCP)vs › | $15.30M | -468.17% | -602.06% | -602.06% | -23374.02% |
| Pulsenmore Ltd. Ordinary Shares (PLSM)vs › | $14.57M | -23.39% | -215.41% | -426.39% | -612.06% |
| Obsidian Therapeutics Inc. (OBX)vs › | $14.51M | N/A | N/A | N/A | N/A |
| Allarity Therapeutics, Inc. (ALLR)vs › | $15.81M | -14633.33% | -7486.14% | -4543.27% | -3157.51% |
| Citius Pharmaceuticals, Inc. (CTXR)vs › | $13.90M | N/A | N/A | N/A | N/A |
| BioCardia, Inc. (BCDA)vs › | $16.08M | -13679.31% | -8051.39% | -4553.85% | -5076.49% |
| Vyome Holdings, Inc. (HIND)vs › | $13.97M | -855.47% | -475.86% | -335.10% | -307.83% |
| Dyadic International, Inc. (DYAI)vs › | $16.49M | -579.88% | -374.35% | -344.55% | -411.92% |
Gross Margin
95.9%
EBITDA Margin
-61.9%
Operating Margin
-56.2%
Net Margin
-153.3%
Formula: EBITDA Margin = (EBITDA / Revenue) × 100
Why EBITDA Margin matters:
EBITDA Margin = EBITDA / Revenue
EBITDA margin measures operating profitability before interest, taxes, depreciation, and amortization as a percentage of revenue.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | EBITDA MARGIN |
|---|---|
| 2026-03-31 | -76.28% |
| 2025-12-31 | -52.30% |
| 2025-09-30 | -34.38% |
| 2025-06-30 | -64.09% |
| 2025-03-31 | -110.54% |
| 2024-12-31 | -102.15% |
| 2024-09-30 | -67.56% |
| 2024-06-30 | -65.51% |
| 2024-03-31 | -101.65% |
| 2023-12-31 | -111.81% |
| 2023-09-30 | -86.59% |
| 2023-06-30 | -78.47% |
| 2023-03-31 | -79.10% |
| 2022-12-31 | -100.52% |
| 2022-09-30 | -84.82% |
| 2022-06-30 | -107.76% |
| 2022-03-31 | -72.18% |
| 2021-12-31 | 37.30% |
| 2021-09-30 | -115.75% |
| 2021-06-30 | -216.00% |
| 2021-03-31 | -224.15% |
| 2020-12-31 | -104.87% |
| 2020-09-30 | -219.73% |
| 2020-06-30 | -119.59% |
| 2020-03-31 | -259.75% |
| 2019-12-31 | -237.74% |
| 2019-09-30 | -297.80% |
| 2019-06-30 | -436.57% |
| 2019-03-31 | -41727.10% |
| 2018-12-31 | -27796.60% |
| 2018-09-30 | -20487.87% |
| 2018-06-30 | -171.68% |
| 2018-03-31 | -387.73% |
| 2017-12-31 | -2560.50% |
| 2017-06-30 | -985733.33% |
| 2017-03-31 | -44258.82% |
| 2016-12-31 | -57414.89% |
| 2016-09-30 | -53256.25% |
| 2016-06-30 | -51350.85% |
| 2015-12-31 | -116504.00% |
| 2015-09-30 | -40593.33% |
| 2015-06-30 | -21904.67% |
| 2014-12-31 | -161312.50% |
| 2014-09-30 | -93514.29% |
| 2014-06-30 | -78123.81% |
| 2014-03-31 | -7993.57% |
| 2013-12-31 | -57666.67% |
| 2013-06-30 | -5139.10% |
| 2013-03-31 | -2393.56% |
| 2012-12-31 | -12751.52% |
| 2012-09-30 | -10591.18% |
