Basis: Trailing twelve months (TTM). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the operating margin high or low?
The operating margin of -4.25% is 95% above its 5-year average of -79.55%, near the high end of its 5-year range (-1452.36%–1.96%).
69.05% above its 12-month average of -13.73%.
Reported quarterly operating margin; no daily interpolation. Q2 FY2026 (2026-06-30): -24.14%.
OPERATING MARGIN
-4.25%
OPERATING MARGIN AVG TTM
-13.73%
OPERATING MARGIN AVG 3Y
-27.25%
OPERATING MARGIN AVG 5Y
-79.55%
OPERATING MARGIN AVG 10Y
N/A
OPERATING MARGIN AVG 15Y
N/A
OPERATING MARGIN AVG 20Y
N/A
CURRENT VS TTM AVG
+69.05%
CURRENT VS 3Y AVG
+84.41%
CURRENT VS 5Y AVG
+94.66%
CURRENT VS 10Y AVG
N/A
CURRENT VS 15Y AVG
N/A
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
0.00%
median of 745 covered companies
CURRENT VS SECTOR MEDIAN
N/A
vs the sector median at left
Mirum Pharmaceuticals, Inc.
Market Cap
$4.86B
Operating Margin
-4.25%
TTM Avg
-13.73%
3Y Avg
-27.25%
5Y Avg
-79.55%
Market Cap
$4.84B
Operating Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
Market Cap
$4.82B
Operating Margin
-8739.34%
TTM Avg
-5186.54%
3Y Avg
-3135.16%
5Y Avg
-2237.88%
Market Cap
$4.70B
Operating Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
Market Cap
$4.69B
Operating Margin
4.95%
TTM Avg
-0.41%
3Y Avg
-10.80%
5Y Avg
-13.67%
Market Cap
$5.09B
Operating Margin
12.75%
TTM Avg
11.82%
3Y Avg
10.28%
5Y Avg
7.77%
Market Cap
$4.65B
Operating Margin
5.94%
TTM Avg
6.21%
3Y Avg
6.46%
5Y Avg
5.84%
Market Cap
$5.14B
Operating Margin
0.00%
TTM Avg
0.00%
3Y Avg
-101.20%
5Y Avg
-276.55%
| NAME | MARKET CAP | OPERATING MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Mirum Pharmaceuticals, Inc. (MIRM) | $4.86B | -4.25% | -13.73% | -27.25% | -79.55% |
| Oruka Therapeutics, Inc. (ORKA)vs › | $4.84B | 0.00% | 0.00% | 0.00% | 0.00% |
| Dianthus Therapeutics, Inc. (DNTH)vs › | $4.82B | -8739.34% | -5186.54% | -3135.16% | -2237.88% |
| Erasca, Inc. (ERAS)vs › | $5.05B | 0.00% | 0.00% | 0.00% | 0.00% |
| Definium Therapeutics, Inc. (DFTX)vs › | $4.70B | 0.00% | 0.00% | 0.00% | 0.00% |
| LifeStance Health Group, Inc. (LFST)vs › | $4.69B | 4.95% | -0.41% | -10.80% | -13.67% |
| Merit Medical Systems, Inc. (MMSI)vs › | $5.09B | 12.75% | 11.82% | 10.28% | 7.77% |
| Option Care Health, Inc. (OPCH)vs › | $4.65B | 5.94% | 6.21% | 6.46% | 5.84% |
| Scholar Rock Holding Corporation (SRRK)vs › | $5.14B | 0.00% | 0.00% | -101.20% | -276.55% |
| BillionToOne, Inc. (BLLN)vs › | $4.56B | 10.90% | -12.82% | -40.85% | -40.85% |
Gross Margin
81.7%
Operating Margin
-4.3%
Operating Margin = Operating Income / Revenue
Operating margin is the percentage of revenue remaining after operating expenses, reflecting operating efficiency.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | OPERATING MARGIN |
|---|---|
| 2026-06-30 | -24.14% |
| 2026-03-31 | -39.51% |
| 2025-12-31 | -3.07% |
| 2025-09-30 | 1.96% |
| 2025-06-30 | -3.90% |
| 2025-03-31 | -13.61% |
| 2024-12-31 | -24.36% |
| 2024-09-30 | -14.03% |
| 2024-06-30 | -31.12% |
| 2024-03-31 | -38.24% |
| 2023-12-31 | -46.85% |
| 2023-09-30 | -52.69% |
| 2023-06-30 | -64.73% |
| 2023-03-31 | -85.92% |
| 2022-12-31 | -122.41% |
| 2022-09-30 | -175.09% |
| 2022-06-30 | -179.83% |
| 2022-03-31 | -253.92% |
| 2021-12-31 | -1452.36% |
| 2021-09-30 | -856.48% |
| 2021-06-30 | -340.01% |
| 2021-03-31 | 0.00% |
| 2020-12-31 | 0.00% |
| 2020-09-30 | 0.00% |
| 2020-06-30 | 0.00% |
| 2020-03-31 | 0.00% |
| 2019-12-31 | 0.00% |
| 2019-09-30 | 0.00% |
| 2019-06-30 | 0.00% |
| 2019-03-31 | 0.00% |
| 2018-12-31 | 0.00% |
| 2018-09-30 | 0.00% |
