Basis: Trailing twelve months (TTM net income over TTM revenue). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the net profit margin high or low?
The net profit margin of -1570.85% is 53% below its 5-year average of -1027.00%, near the low end of its 5-year range (-16388.08%–34473.59%).
18.71% below its 12-month average of -1323.32%.
Reported quarterly profit margin; no daily interpolation. Q2 FY2026 (2026-06-30): -6598.55%.
NET PROFIT MARGIN
-1570.85%
NET PROFIT MARGIN AVG TTM
-1323.32%
NET PROFIT MARGIN AVG 3Y
-3465.47%
NET PROFIT MARGIN AVG 5Y
-1027.00%
NET PROFIT MARGIN AVG 10Y
-497.94%
NET PROFIT MARGIN AVG 15Y
N/A
NET PROFIT MARGIN AVG 20Y
N/A
CURRENT VS TTM AVG
-18.71%
CURRENT VS 3Y AVG
+54.67%
CURRENT VS 5Y AVG
-52.96%
CURRENT VS 10Y AVG
-215.47%
CURRENT VS 15Y AVG
N/A
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
0.00%
median of 673 covered companies
CURRENT VS SECTOR MEDIAN
N/A
vs the sector median at left
Dianthus Therapeutics, Inc.
Market Cap
$4.86B
Net Profit Margin
-1570.85%
TTM Avg
-1323.32%
3Y Avg
-3465.47%
5Y Avg
-1027.00%
Market Cap
$4.89B
Net Profit Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
Market Cap
$4.91B
Net Profit Margin
-139.18%
TTM Avg
-15.29%
3Y Avg
-73.58%
5Y Avg
-122.19%
Market Cap
$4.72B
Net Profit Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
Market Cap
$4.68B
Net Profit Margin
3.19%
TTM Avg
-1.95%
3Y Avg
-11.66%
5Y Avg
-17.12%
Market Cap
$5.08B
Net Profit Margin
9.22%
TTM Avg
8.68%
3Y Avg
7.83%
5Y Avg
5.80%
Market Cap
$4.65B
Net Profit Margin
3.68%
TTM Avg
3.96%
3Y Avg
4.48%
5Y Avg
3.62%
Market Cap
$4.59B
Net Profit Margin
8.43%
TTM Avg
-12.40%
3Y Avg
-46.69%
5Y Avg
-46.69%
| NAME | MARKET CAP | NET PROFIT MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Dianthus Therapeutics, Inc. (DNTH) | $4.86B | -1570.85% | -1323.32% | -3465.47% | -1027.00% |
| Oruka Therapeutics, Inc. (ORKA)vs › | $4.89B | 0.00% | 0.00% | 0.00% | 0.00% |
| Mirum Pharmaceuticals, Inc. (MIRM)vs › | $4.91B | -139.18% | -15.29% | -73.58% | -122.19% |
| Definium Therapeutics, Inc. (DFTX)vs › | $4.72B | 0.00% | 0.00% | 0.00% | 0.00% |
| LifeStance Health Group, Inc. (LFST)vs › | $4.68B | 3.19% | -1.95% | -11.66% | -17.12% |
| Merit Medical Systems, Inc. (MMSI)vs › | $5.08B | 9.22% | 8.68% | 7.83% | 5.80% |
| Option Care Health, Inc. (OPCH)vs › | $4.65B | 3.68% | 3.96% | 4.48% | 3.62% |
| Erasca, Inc. (ERAS)vs › | $5.10B | 0.00% | 0.00% | 0.00% | 0.00% |
| BillionToOne, Inc. (BLLN)vs › | $4.59B | 8.43% | -12.40% | -46.69% | -46.69% |
| Scholar Rock Holding Corporation (SRRK)vs › | $5.23B | 0.00% | 0.00% | -101.30% | -277.86% |
Operating Margin
-8739.3%
Net Profit Margin
-1570.8%
Net Profit Margin = Net Income / Revenue
Net profit margin is the percentage of revenue that becomes net income after all expenses, taxes, and interest.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | NET PROFIT MARGIN |
|---|---|
| 2026-06-30 | -6598.55% |
| 2026-03-31 | -8819.44% |
| 2025-12-31 | 34473.59% |
| 2025-09-30 | -9284.09% |
| 2025-06-30 | -16388.08% |
| 2025-03-31 | -2537.49% |
| 2024-12-31 | -2144.80% |
| 2024-09-30 | -1159.02% |
| 2024-06-30 | -945.09% |
| 2024-03-31 | -1573.00% |
| 2023-12-31 | -2311.38% |
| 2023-09-30 | -1597.73% |
| 2023-06-30 | -1149.64% |
| 2023-03-31 | -1489.29% |
| 2022-12-31 | -860.94% |
| 2022-09-30 | -663.60% |
| 2022-06-30 | 0.00% |
| 2022-03-31 | 0.00% |
| 2021-12-31 | 0.00% |
| 2021-09-30 | 0.00% |
| 2021-06-30 | 0.00% |
| 2021-03-31 | 0.00% |
| 2020-12-31 | 0.00% |
| 2020-09-30 | 0.00% |
| 2020-06-30 | 0.00% |
| 2020-03-31 | 0.00% |
| 2019-12-31 | 0.00% |
| 2019-09-30 | 0.00% |
| 2019-06-30 | 0.00% |
| 2019-03-31 | 0.00% |
| 2018-12-31 | 0.00% |
| 2018-09-30 | 0.00% |
| 2018-06-30 | 0.00% |
| 2018-03-31 | 0.00% |
| 2017-12-31 | 0.00% |
| 2017-09-30 | 0.00% |
| 2017-06-30 | 0.00% |
| 2017-03-31 | 0.00% |
