Is DNTH or OPCH more profitable?

OPCH runs the higher net margin — DNTH at -1570.85% versus OPCH at 3.68%.

How have DNTH and OPCH total returns compared?

Over the past 5 years, DNTH delivered -5.50% and OPCH delivered -1.37% annualized total return. Past performance doesn't predict future results.

Dianthus Therapeutics, Inc. (DNTH) vs Option Care Health, Inc. (OPCH)

A side-by-side comparison of Dianthus Therapeutics, Inc. and Option Care Health, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

DNTH

Dianthus Therapeutics, Inc.

$4.85B

$86.71HealthcareDelayed quote: Oct 6, 2026, 11:55 AM EDT

OPCH

Option Care Health, Inc.

$4.65B

$31.05HealthcareDelayed quote: Oct 6, 2026, 11:55 AM EDT

Total return — DNTH vs OPCH

growth of $100 · dividends reinvested · last 8y

DNTH -62.1% (-11.4%/yr)OPCH +130.0% (+11.0%/yr)OPCH compounded faster over this window

Log scale — wide-divergence pair

DNTH OPCH

DNTH vs OPCH: by the numbers

•DNTH is the larger company ($4.85B vs $4.65B market cap).
•OPCH is profitable (3.68% net margin) while DNTH runs a net loss (-1570.85%).

Metrics side by side

Valuation

Metric	DNTH	OPCH
P/E ratio	N/A	23.35
Forward P/E	N/A	16.52
P/S ratio	2547.37	0.82
P/B ratio	4.14	3.69
EV / EBITDA	N/A	13.97

Profitability

Metric	DNTH	OPCH
Gross margin	96.01%	18.17%
Operating margin	-8739.34%	5.94%
Net margin	-1570.85%	3.68%
ROE	-2.55%	16.63%
ROIC	-18.48%	9.68%

Growth (annualized)

Metric	DNTH	OPCH
Revenue CAGR (5Y)	N/A	12.17%
Total return CAGR (5Y)	-5.50%	-1.37%

Frequently asked

Is DNTH or OPCH more profitable?: OPCH runs the higher net margin — DNTH at -1570.85% versus OPCH at 3.68%.
How have DNTH and OPCH total returns compared?: Over the past 5 years, DNTH delivered -5.50% and OPCH delivered -1.37% annualized total return. Past performance doesn't predict future results.

Go deeper

Full DNTH analysis Full OPCH analysis Interactive comparison tool

Dig into the metrics

Option Care Health P/E ratio Dianthus Therapeutics ROE Option Care Health ROE Dianthus Therapeutics operating margin Option Care Health operating margin Dianthus Therapeutics revenue growth Option Care Health revenue growth Dianthus Therapeutics free cash flow Option Care Health free cash flow

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.