Basis: Trailing twelve months (TTM net income over TTM revenue). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the net profit margin high or low?
The net profit margin of -39.55% is 53% above its 5-year average of -83.61%, near the high end of its 5-year range (-376.29%–24.67%).
53.75% above its 12-month average of -85.51%.
Reported quarterly profit margin; no daily interpolation. Q2 FY2026 (2026-06-30): -80.49%.
NET PROFIT MARGIN
-39.55%
NET PROFIT MARGIN AVG TTM
-85.51%
NET PROFIT MARGIN AVG 3Y
-132.38%
NET PROFIT MARGIN AVG 5Y
-83.61%
NET PROFIT MARGIN AVG 10Y
-34.02%
NET PROFIT MARGIN AVG 15Y
-45.75%
NET PROFIT MARGIN AVG 20Y
-44.29%
CURRENT VS TTM AVG
+53.75%
CURRENT VS 3Y AVG
+70.12%
CURRENT VS 5Y AVG
+52.70%
CURRENT VS 10Y AVG
-16.25%
CURRENT VS 15Y AVG
+13.56%
CURRENT VS 20Y AVG
+10.70%
SECTOR MEDIAN · HEALTHCARE
0.00%
median of 509 covered companies
CURRENT VS SECTOR MEDIAN
N/A
vs the sector median at left
Codexis, Inc.
Market Cap
$150.59M
Net Profit Margin
-39.55%
TTM Avg
-85.51%
3Y Avg
-132.38%
5Y Avg
-83.61%
Market Cap
$153.31M
Net Profit Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
-6695.15%
Market Cap
$153.84M
Net Profit Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
Market Cap
$147.02M
Net Profit Margin
0.00%
TTM Avg
0.00%
3Y Avg
-3984.32%
5Y Avg
-3047.80%
Market Cap
$154.28M
Net Profit Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
-85.02%
Market Cap
$154.72M
Net Profit Margin
-10.40%
TTM Avg
-6.28%
3Y Avg
-16.07%
5Y Avg
-47.85%
Market Cap
$143.81M
Net Profit Margin
-353.00%
TTM Avg
-161.48%
3Y Avg
-3791.01%
5Y Avg
-3351.38%
Market Cap
$142.49M
Net Profit Margin
163.32%
TTM Avg
-34.49%
3Y Avg
-63.76%
5Y Avg
-75.19%
Market Cap
$142.11M
Net Profit Margin
-153.61%
TTM Avg
-101.12%
3Y Avg
-50.56%
5Y Avg
-33.71%
| NAME | MARKET CAP | NET PROFIT MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Codexis, Inc. (CDXS) | $150.59M | -39.55% | -85.51% | -132.38% | -83.61% |
| Cardiol Therapeutics Inc. (CRDL)vs › | $153.31M | 0.00% | 0.00% | 0.00% | -6695.15% |
| Anavex Life Sciences Corp. (AVXL)vs › | $153.84M | 0.00% | 0.00% | 0.00% | 0.00% |
| Immuneering Corporation (IMRX)vs › | $147.02M | 0.00% | 0.00% | -3984.32% | -3047.80% |
| Acumen Pharmaceuticals, Inc. (ABOS)vs › | $154.28M | 0.00% | 0.00% | 0.00% | -85.02% |
| LifeMD, Inc. (LFMDP)vs › | $154.72M | -10.40% | -6.28% | -16.07% | -47.85% |
| Korsana Biosciences, Inc. (KRSA)vs › | $143.81M | -353.00% | -161.48% | -3791.01% | -3351.38% |
| Fortress Biotech, Inc. (FBIOP)vs › | $142.49M | 163.32% | -34.49% | -63.76% | -75.19% |
| Alpha Cognition Inc (ACOG)vs › | $142.11M | -153.61% | -101.12% | -50.56% | -33.71% |
| ALX Oncology Holdings Inc. (ALXO)vs › | $160.13M | 0.00% | 0.00% | 0.00% | -644.95% |
Operating Margin
-54.5%
Net Profit Margin
-39.5%
Net Profit Margin = Net Income / Revenue
Net profit margin is the percentage of revenue that becomes net income after all expenses, taxes, and interest.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | NET PROFIT MARGIN |
|---|---|
| 2026-06-30 | -80.49% |
| 2026-03-31 | -57.08% |
| 2025-12-31 | 24.67% |
| 2025-09-30 | -228.05% |
| 2025-06-30 | -86.59% |
| 2025-03-31 | -274.27% |
| 2024-12-31 | -48.35% |
| 2024-09-30 | -160.84% |
| 2024-06-30 | -285.19% |
| 2024-03-31 | -67.39% |
| 2023-12-31 | -27.08% |
| 2023-09-30 | -376.29% |
| 2023-06-30 | -54.04% |
| 2023-03-31 | -174.22% |
| 2022-12-31 | -41.49% |
| 2022-09-30 | -28.99% |
| 2022-06-30 | -6.87% |
| 2022-03-31 | -23.64% |
| 2021-12-31 | -41.59% |
| 2021-09-30 | 6.10% |
| 2021-06-30 | -16.76% |
| 2021-03-31 | -50.29% |
| 2020-12-31 | -18.64% |
| 2020-09-30 | -33.15% |
| 2020-06-30 | -42.39% |
| 2020-03-31 | -52.16% |
| 2019-12-31 | -3.40% |
| 2019-09-30 | 1.57% |
| 2019-06-30 | -52.82% |
| 2019-03-31 | -32.96% |
| 2018-12-31 | -2.87% |
| 2018-09-30 | -11.73% |
| 2018-06-30 | -27.59% |
| 2018-03-31 | -33.43% |
| 2017-12-31 | 4.47% |
| 2017-09-30 | -102.42% |
| 2017-06-30 | -60.69% |
| 2017-03-31 | -93.59% |
| 2016-12-31 | -52.76% |
| 2016-09-30 | 9.66% |
| 2016-06-30 | 13.99% |
| 2016-03-31 | -87.22% |
| 2015-12-31 | -17.72% |
| 2015-09-30 | 31.00% |
| 2015-06-30 | -89.07% |
| 2015-03-31 | -81.82% |
| 2014-12-31 | 2.43% |
| 2014-09-30 | -61.05% |
| 2014-06-30 | -129.06% |
| 2014-03-31 | -90.12% |
| 2013-12-31 | -103.02% |
| 2013-09-30 | -234.90% |
| 2013-06-30 | -180.74% |
| 2013-03-31 | -83.82% |
| 2012-12-31 | -196.39% |
| 2012-09-30 | -8.77% |
| 2012-06-30 | -24.09% |
| 2012-03-31 | -24.06% |
| 2011-12-31 | -15.81% |
| 2011-09-30 | -8.24% |
| 2011-06-30 | -19.34% |
| 2011-03-31 | -11.18% |
| 2010-12-31 | -1.66% |
| 2010-09-30 | -10.08% |
| 2010-06-30 | -16.12% |
| 2010-03-31 | -5.33% |
| 2009-12-31 | -21.37% |
| 2009-09-30 | -30.69% |
| 2009-06-30 | -14.89% |
| 2009-03-31 | -31.39% |
| 2008-12-31 | -34.02% |
| 2008-03-31 | -166.10% |
| 2007-03-31 | -108.33% |
