Basis: Trailing twelve months (TTM). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the operating margin high or low?
The operating margin of -54.46% is 31% above its 5-year average of -79.38%, near the high end of its 5-year range (-345.59%–35.89%).
31.30% above its 12-month average of -79.27%.
Reported quarterly operating margin; no daily interpolation. Q2 FY2026 (2026-06-30): -75.29%.
OPERATING MARGIN
-54.46%
OPERATING MARGIN AVG TTM
-79.27%
OPERATING MARGIN AVG 3Y
-122.27%
OPERATING MARGIN AVG 5Y
-79.38%
OPERATING MARGIN AVG 10Y
-35.42%
OPERATING MARGIN AVG 15Y
-44.54%
OPERATING MARGIN AVG 20Y
-43.04%
CURRENT VS TTM AVG
+31.30%
CURRENT VS 3Y AVG
+55.46%
CURRENT VS 5Y AVG
+31.39%
CURRENT VS 10Y AVG
-53.75%
CURRENT VS 15Y AVG
-22.26%
CURRENT VS 20Y AVG
-26.52%
SECTOR MEDIAN · HEALTHCARE
0.00%
median of 558 covered companies
CURRENT VS SECTOR MEDIAN
N/A
vs the sector median at left
Codexis, Inc.
Market Cap
$154.76M
Operating Margin
-54.46%
TTM Avg
-79.27%
3Y Avg
-122.27%
5Y Avg
-79.38%
Market Cap
$153.56M
Operating Margin
-9.35%
TTM Avg
-5.78%
3Y Avg
-14.39%
5Y Avg
-45.18%
Market Cap
$155.62M
Operating Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
-8182.07%
Market Cap
$158.01M
Operating Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
Market Cap
$156.62M
Operating Margin
N/A
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
Market Cap
$148.07M
Operating Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
-91.83%
Market Cap
$160.80M
Operating Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
-615.66%
Market Cap
$159.74M
Operating Margin
-8.45%
TTM Avg
-10.66%
3Y Avg
-19.64%
5Y Avg
-13.31%
Market Cap
$146.95M
Operating Margin
-239.78%
TTM Avg
-210.59%
3Y Avg
-1665.90%
5Y Avg
-1977.59%
| NAME | MARKET CAP | OPERATING MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Codexis, Inc. (CDXS) | $154.76M | -54.46% | -79.27% | -122.27% | -79.38% |
| LifeMD, Inc. (LFMDP)vs › | $153.56M | -9.35% | -5.78% | -14.39% | -45.18% |
| Cardiol Therapeutics Inc. (CRDL)vs › | $155.62M | 0.00% | 0.00% | 0.00% | -8182.07% |
| Anavex Life Sciences Corp. (AVXL)vs › | $158.01M | 0.00% | 0.00% | 0.00% | 0.00% |
| Jyong Biotech Ltd. Ordinary Shares (MENS)vs › | $156.62M | N/A | 0.00% | 0.00% | 0.00% |
| Acumen Pharmaceuticals, Inc. (ABOS)vs › | $148.07M | 0.00% | 0.00% | 0.00% | -91.83% |
| ALX Oncology Holdings Inc. (ALXO)vs › | $160.80M | 0.00% | 0.00% | 0.00% | -615.66% |
| Inogen, Inc. (INGN)vs › | $159.74M | -8.45% | -10.66% | -19.64% | -13.31% |
| Korsana Biosciences, Inc. (KRSA)vs › | $146.95M | -239.78% | -210.59% | -1665.90% | -1977.59% |
| Immuneering Corporation (IMRX)vs › | $145.39M | 0.00% | 0.00% | -4081.44% | -3115.66% |
Gross Margin
83.7%
Operating Margin
-54.5%
Operating Margin = Operating Income / Revenue
Operating margin is the percentage of revenue remaining after operating expenses, reflecting operating efficiency.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | OPERATING MARGIN |
|---|---|
| 2026-06-30 | -75.29% |
| 2026-03-31 | -52.75% |
| 2025-12-31 | 35.89% |
| 2025-09-30 | -220.31% |
| 2025-06-30 | -83.91% |
| 2025-03-31 | -271.59% |
| 2024-12-31 | -34.21% |
| 2024-09-30 | -129.02% |
| 2024-06-30 | -284.90% |
| 2024-03-31 | -69.63% |
| 2023-12-31 | 1.06% |
| 2023-09-30 | -345.59% |
| 2023-06-30 | -59.21% |
| 2023-03-31 | -182.29% |
| 2022-12-31 | -43.62% |
| 2022-09-30 | -30.86% |
| 2022-06-30 | -6.79% |
| 2022-03-31 | -23.73% |
| 2021-12-31 | -42.39% |
| 2021-09-30 | 3.62% |
| 2021-06-30 | -17.62% |
| 2021-03-31 | -50.77% |
| 2020-12-31 | -18.66% |
| 2020-09-30 | -32.98% |
| 2020-06-30 | -40.80% |
| 2020-03-31 | -53.35% |
| 2019-12-31 | -5.08% |
| 2019-09-30 | 1.18% |
| 2019-06-30 | -53.76% |
| 2019-03-31 | -33.62% |
| 2018-12-31 | -4.01% |
| 2018-09-30 | -12.43% |
| 2018-06-30 | -28.35% |
| 2018-03-31 | -33.52% |
| 2017-12-31 | 4.05% |
| 2017-09-30 | -100.52% |
| 2017-06-30 | -61.24% |
| 2017-03-31 | -93.79% |
| 2016-12-31 | -52.66% |
| 2016-09-30 | 9.54% |
| 2016-06-30 | 14.05% |
| 2016-03-31 | -87.31% |
| 2015-12-31 | -19.27% |
| 2015-09-30 | 32.70% |
| 2015-06-30 | -94.68% |
| 2015-03-31 | -81.33% |
| 2014-12-31 | 3.17% |
| 2014-09-30 | -56.95% |
| 2014-06-30 | -135.63% |
| 2014-03-31 | -90.42% |
| 2013-12-31 | -103.42% |
| 2013-09-30 | -233.68% |
| 2013-06-30 | -178.52% |
| 2013-03-31 | -83.88% |
| 2012-12-31 | -199.03% |
| 2012-09-30 | -8.18% |
| 2012-06-30 | -23.39% |
| 2012-03-31 | -23.28% |
| 2011-12-31 | -14.64% |
| 2011-09-30 | -7.01% |
| 2011-06-30 | -20.31% |
| 2011-03-31 | -10.89% |
| 2010-12-31 | -1.05% |
| 2010-09-30 | -9.07% |
| 2010-06-30 | -13.28% |
| 2010-03-31 | -4.28% |
| 2009-12-31 | -19.49% |
| 2009-09-30 | -27.39% |
| 2009-06-30 | -13.04% |
| 2009-03-31 | -29.07% |
| 2008-12-31 | -34.31% |
| 2008-03-31 | -156.51% |
| 2007-03-31 | -115.77% |
