Codexis (CDXS) Gross Profit Margin: History & Chart

Codexis, Inc.(CDXS)

Biotechnology · Redwood City, CA

$1.41+0.02 (+1.62%)

Delayed quote: Oct 6, 2026, 11:34 AM EDT

About Codexis, Inc.

Codexis, Inc. is a biotechnology firm dedicated to the discovery, development, and commercialization of enzymes and other protein-based solutions. Its diverse portfolio encompasses advanced biocatalyst products and related services, specialized chemical intermediates vital for subsequent processing steps, and proprietary biocatalyst panels and kits that empower clients to conduct effective chemistry screening. The company also extends its expertise through biocatalyst screening and sophisticated protein engineering services. Central to its operations is the proprietary CodeEvolver protein engineering technology platform. This innovative platform is instrumental in crafting and delivering high-performance biocatalysts capable of driving chemical transformations, thereby significantly enhancing the efficiency and productivity of manufacturing processes. Beyond industrial applications, the CodeEvolver platform is also leveraged for identifying novel biotherapeutic drug candidates for targeted human diseases, as well as for developing enzymes essential for molecular biology research and in vitro diagnostic applications. Primarily serving pharmaceutical manufacturers, Codexis distributes its products through its dedicated direct sales and business development teams across the United States and Europe. Established in 2002, the company maintains its headquarters in Redwood City, California.

Redwood City, CA

146 employees

www.codexis.com

Healthcare / Biotechnology

Sector: Healthcare
Industry: Biotechnology
CEO: Alison Moore

View full financials

CDXS Gross Margin Metrics

GROSS MARGIN

83.71%

GROSS MARGIN AVG TTM

79.05%

GROSS MARGIN AVG 3Y

74.98%

GROSS MARGIN AVG 5Y

74.61%

GROSS MARGIN AVG 10Y

75.74%

GROSS MARGIN AVG 15Y

74.41%

GROSS MARGIN AVG 20Y

75.02%

CURRENT VS TTM AVG

+5.89%

CURRENT VS 3Y AVG

+11.65%

CURRENT VS 5Y AVG

+12.20%

CURRENT VS 10Y AVG

+10.52%

CURRENT VS 15Y AVG

+12.49%

CURRENT VS 20Y AVG

+11.59%

SECTOR MEDIAN · HEALTHCARE

39.32%

median of 679 covered companies

CURRENT VS SECTOR MEDIAN

+112.89%

vs the sector median at left

NAME	MARKET CAP	GROSS MARGIN	TTM	3Y	5Y
Codexis, Inc. (CDXS)	$151.93M	83.71%	79.05%	74.98%	74.61%
Anavex Life Sciences Corp. (AVXL)vs ›	$152.63M	0.00%	0.00%	0.00%	0.00%
Cardiol Therapeutics Inc. (CRDL)vs ›	$154.46M	0.00%	0.00%	0.00%	-29.98%
Acumen Pharmaceuticals, Inc. (ABOS)vs ›	$150.96M	0.00%	0.00%	0.00%	-76.15%
ALX Oncology Holdings Inc. (ALXO)vs ›	$155.42M	0.00%	0.00%	0.00%	1.51%
Jyong Biotech Ltd. Ordinary Shares (MENS)vs ›	$155.86M	N/A	0.00%	0.00%	0.00%
Minerva Neurosciences, Inc. (NERV)vs ›	$157.44M	0.00%	0.00%	0.00%	16.67%
LifeMD, Inc. (LFMDP)vs ›	$147.97M	85.91%	84.21%	85.09%	82.87%
NervGen Pharma Corp. Common stock (NGEN)vs ›	$147.54M	0.00%	0.00%	0.00%	0.00%
Inogen, Inc. (INGN)vs ›	$157.30M	48.89%	46.84%	43.63%	44.77%

NAME

MARKET CAP

GROSS MARGIN

TTM

Codexis, Inc. (CDXS)

$151.93M

83.71%

79.05%

74.98%

74.61%

Anavex Life Sciences Corp. (AVXL)vs ›

$152.63M

0.00%

Cardiol Therapeutics Inc. (CRDL)vs ›

$154.46M

0.00%

-29.98%

Acumen Pharmaceuticals, Inc. (ABOS)vs ›

$150.96M

0.00%

-76.15%

ALX Oncology Holdings Inc. (ALXO)vs ›

$155.42M

0.00%

1.51%

Jyong Biotech Ltd. Ordinary Shares (MENS)vs ›

$155.86M

N/A

0.00%

Minerva Neurosciences, Inc. (NERV)vs ›

$157.44M

0.00%

16.67%

LifeMD, Inc. (LFMDP)vs ›

$147.97M

85.91%

84.21%

85.09%

82.87%

NervGen Pharma Corp. Common stock (NGEN)vs ›

$147.54M

0.00%

Inogen, Inc. (INGN)vs ›

$157.30M

48.89%

46.84%

43.63%

44.77%

Gross Margin FAQ

What is the gross margin for Codexis, Inc. (CDXS)?

The gross margin for CDXS stock is 83.71%.

Is Codexis, Inc.'s gross margin high or low?

The gross margin of 83.71% is 12% above its 5-year average of 74.61%, near the high end of its 5-year range (56.61%–91.36%).

What is the TTM average gross margin for Codexis, Inc. (CDXS)?

The TTM average gross margin for CDXS stock is 79.05%.

What is the 3Y average gross margin for Codexis, Inc. (CDXS)?

The 3Y average gross margin for CDXS stock is 74.98%.

What is the 5Y average gross margin for Codexis, Inc. (CDXS)?

The 5Y average gross margin for CDXS stock is 74.61%.

What is the 10Y average gross margin for Codexis, Inc. (CDXS)?

The 10Y average gross margin for CDXS stock is 75.74%.

What is the 15Y average gross margin for Codexis, Inc. (CDXS)?

The 15Y average gross margin for CDXS stock is 74.41%.

What is the 20Y average gross margin for Codexis, Inc. (CDXS)?

The 20Y average gross margin for CDXS stock is 75.02%.

DATE	GROSS MARGIN
2026-06-30	76.45%
2026-03-31	78.28%
2025-12-31	91.36%
2025-09-30	71.34%
2025-06-30	77.82%
2025-03-31	63.78%
2024-12-31	82.97%
2024-09-30	66.36%
2024-06-30	56.61%
2024-03-31	64.23%
2023-12-31	84.65%
2023-09-30	75.76%
2023-06-30	85.10%
2023-03-31	65.17%
2022-12-31	72.16%
2022-09-30	71.61%
2022-06-30	70.66%
2022-03-31	75.89%
2021-12-31	72.22%
2021-09-30	81.32%
2021-06-30	83.04%
2021-03-31	76.61%
2020-12-31	72.14%
2020-09-30	80.19%
2020-06-30	88.65%
2020-03-31	82.68%
2019-12-31	81.76%
2019-09-30	76.87%
2019-06-30	77.50%
2019-03-31	71.82%
2018-12-31	85.11%
2018-09-30	77.63%
2018-06-30	80.71%
2018-03-31	72.76%
2017-12-31	83.62%
2017-09-30	60.18%
2017-06-30	63.37%
2017-03-31	62.34%
2016-12-31	77.06%
2016-09-30	81.47%
2016-06-30	86.12%
2016-03-31	68.87%
2015-12-31	77.75%
2015-09-30	92.52%
2015-06-30	79.23%
2015-03-31	78.58%
2014-12-31	75.01%
2014-09-30	79.50%
2014-06-30	67.69%
2014-03-31	64.32%
2013-12-31	49.98%
2013-09-30	87.47%
2013-06-30	47.94%
2013-03-31	50.66%
2012-12-31	26.96%
2012-09-30	75.71%
2012-06-30	74.56%
2012-03-31	59.40%
2011-12-31	60.98%
2011-09-30	70.08%
2011-06-30	72.73%
2011-03-31	62.46%
2010-12-31	72.74%
2010-09-30	68.42%
2010-06-30	75.18%
2010-03-31	79.70%
2009-12-31	80.23%
2009-09-30	76.98%
2009-06-30	82.23%
2009-03-31	80.13%
2008-12-31	71.69%
2008-03-31	65.52%
2007-03-31	71.28%

DATE

GROSS MARGIN

2026-06-30

76.45%

2026-03-31

78.28%

2025-12-31

91.36%

2025-09-30

71.34%

2025-06-30

77.82%

2025-03-31

63.78%

2024-12-31

82.97%

2024-09-30

66.36%

2024-06-30

56.61%

2024-03-31

64.23%

2023-12-31

84.65%

2023-09-30

75.76%

2023-06-30

85.10%

2023-03-31

65.17%

2022-12-31

72.16%

2022-09-30

71.61%

2022-06-30

70.66%

2022-03-31

75.89%

2021-12-31

72.22%

2021-09-30

81.32%

2021-06-30

83.04%

2021-03-31

76.61%

2020-12-31

72.14%

2020-09-30

80.19%

2020-06-30

88.65%

2020-03-31

82.68%

2019-12-31

81.76%

2019-09-30

76.87%

2019-06-30

77.50%

2019-03-31

71.82%

2018-12-31

85.11%

2018-09-30

77.63%

2018-06-30

80.71%

2018-03-31

72.76%

2017-12-31

83.62%

2017-09-30

60.18%

2017-06-30

63.37%

2017-03-31

62.34%

2016-12-31

77.06%

2016-09-30

81.47%

2016-06-30

86.12%

2016-03-31

68.87%

2015-12-31

77.75%

2015-09-30

92.52%

2015-06-30

79.23%

2015-03-31

78.58%

2014-12-31

75.01%

2014-09-30

79.50%

2014-06-30

67.69%

2014-03-31

64.32%

2013-12-31

49.98%

2013-09-30

87.47%

2013-06-30

47.94%

2013-03-31

50.66%

2012-12-31

26.96%

2012-09-30

75.71%

2012-06-30

74.56%

2012-03-31

59.40%

2011-12-31

60.98%

2011-09-30

70.08%

2011-06-30

72.73%

2011-03-31

62.46%

2010-12-31

72.74%

2010-09-30

68.42%

2010-06-30

75.18%

2010-03-31

79.70%

2009-12-31

80.23%

2009-09-30

76.98%

2009-06-30

82.23%

2009-03-31

80.13%

2008-12-31

71.69%

2008-03-31

65.52%

2007-03-31

71.28%

Gross Margin: 83.71%

CDXS Gross Margin

CDXS Average Gross Margin Chart

CDXS Current vs Average Gross Margin Chart

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Gross Margin Analysis

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CDXS Gross Margin History

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