Basis: Trailing twelve months (TTM). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the operating margin high or low?
The operating margin of -24.28% is 58% above its 5-year average of -58.22%, near the high end of its 5-year range (-444.23%–0.00%).
0.75% above its 12-month average of -24.46%.
Reported quarterly operating margin; no daily interpolation. Q2 FY2026 (2026-06-30): -22.73%.
OPERATING MARGIN
-24.28%
OPERATING MARGIN AVG TTM
-24.46%
OPERATING MARGIN AVG 3Y
-65.66%
OPERATING MARGIN AVG 5Y
-58.22%
OPERATING MARGIN AVG 10Y
-16.21%
OPERATING MARGIN AVG 15Y
N/A
OPERATING MARGIN AVG 20Y
N/A
CURRENT VS TTM AVG
+0.75%
CURRENT VS 3Y AVG
+63.02%
CURRENT VS 5Y AVG
+58.30%
CURRENT VS 10Y AVG
-49.77%
CURRENT VS 15Y AVG
N/A
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
0.00%
median of 556 covered companies
CURRENT VS SECTOR MEDIAN
N/A
vs the sector median at left
Axsome Therapeutics, Inc.
Market Cap
$8.90B
Operating Margin
-24.28%
TTM Avg
-24.46%
3Y Avg
-65.66%
5Y Avg
-58.22%
Market Cap
$8.77B
Operating Margin
5.56%
TTM Avg
-28.40%
3Y Avg
-70.84%
5Y Avg
-47.21%
Market Cap
$8.74B
Operating Margin
-891.33%
TTM Avg
-723.58%
3Y Avg
-500.53%
5Y Avg
-379.37%
Market Cap
$8.64B
Operating Margin
11.86%
TTM Avg
-8457.60%
3Y Avg
-4268.44%
5Y Avg
-2881.23%
Market Cap
$9.35B
Operating Margin
3.61%
TTM Avg
7.20%
3Y Avg
11.56%
5Y Avg
12.63%
Market Cap
$8.40B
Operating Margin
4.07%
TTM Avg
-1.39%
3Y Avg
-5.39%
5Y Avg
-20.02%
Market Cap
$9.56B
Operating Margin
3.61%
TTM Avg
7.20%
3Y Avg
11.56%
5Y Avg
12.63%
Market Cap
$9.70B
Operating Margin
44.93%
TTM Avg
32.03%
3Y Avg
-38.09%
5Y Avg
-25.39%
| NAME | MARKET CAP | OPERATING MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Axsome Therapeutics, Inc. (AXSM) | $8.90B | -24.28% | -24.46% | -65.66% | -58.22% |
| Caris Life Sciences, Inc. (CAI)vs › | $8.77B | 5.56% | -28.40% | -70.84% | -47.21% |
| Kymera Therapeutics, Inc. (KYMR)vs › | $8.74B | -891.33% | -723.58% | -500.53% | -379.37% |
| Arrowhead Pharmaceuticals, Inc. (ARWR)vs › | $8.64B | 11.86% | -8457.60% | -4268.44% | -2881.23% |
| Insulet Corp. (PODD)vs › | $9.34B | 16.89% | 16.20% | 12.06% | 10.90% |
| Bruker Corporation (BRKRP)vs › | $9.35B | 3.61% | 7.20% | 11.56% | 12.63% |
| Oscar Health, Inc. (OSCR)vs › | $8.40B | 4.07% | -1.39% | -5.39% | -20.02% |
| Bruker Corporation (BRKR)vs › | $9.56B | 3.61% | 7.20% | 11.56% | 12.63% |
| Krystal Biotech, Inc. (KRYS)vs › | $9.70B | 44.93% | 32.03% | -38.09% | -25.39% |
| Henry Schein, Inc. (HSIC)vs › | $9.73B | 5.69% | 5.75% | 6.18% | 6.20% |
Gross Margin
93.2%
Operating Margin
-24.3%
Operating Margin = Operating Income / Revenue
Operating margin is the percentage of revenue remaining after operating expenses, reflecting operating efficiency.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | OPERATING MARGIN |
|---|---|
| 2026-06-30 | -22.73% |
| 2026-03-31 | -33.14% |
| 2025-12-31 | -15.02% |
| 2025-09-30 | -26.97% |
| 2025-06-30 | -24.47% |
| 2025-03-31 | -46.91% |
| 2024-12-31 | -61.14% |
| 2024-09-30 | -59.78% |
| 2024-06-30 | -89.54% |
| 2024-03-31 | -89.70% |
| 2023-12-31 | -137.39% |
| 2023-09-30 | -107.49% |
| 2023-06-30 | -139.31% |
| 2023-03-31 | -6.74% |
| 2022-12-31 | -245.85% |
| 2022-09-30 | -251.76% |
| 2022-06-30 | -444.23% |
| 2022-03-31 | 0.00% |
| 2021-12-31 | 0.00% |
| 2021-09-30 | 0.00% |
| 2021-06-30 | 0.00% |
| 2021-03-31 | 0.00% |
| 2020-12-31 | 0.00% |
| 2020-09-30 | 0.00% |
| 2020-06-30 | 0.00% |
| 2020-03-31 | 0.00% |
| 2019-12-31 | 0.00% |
| 2019-09-30 | 0.00% |
| 2019-06-30 | 0.00% |
| 2019-03-31 | 0.00% |
| 2018-12-31 | 0.00% |
| 2018-09-30 | 0.00% |
| 2018-06-30 | 0.00% |
| 2018-03-31 | 0.00% |
| 2017-12-31 | 0.00% |
| 2017-09-30 | 0.00% |
| 2017-06-30 | 0.00% |
| 2017-03-31 | 0.00% |
| 2016-12-31 | 0.00% |
| 2016-09-30 | 0.00% |
| 2016-06-30 | 0.00% |
| 2016-03-31 | 0.00% |
| 2015-12-31 | 0.00% |
| 2015-09-30 | 0.00% |
| 2015-06-30 | 0.00% |
| 2015-03-31 | 0.00% |
| 2014-12-31 | 0.00% |
| 2014-09-30 | 0.00% |
| 2014-06-30 | 0.00% |
| 2014-03-31 | 0.00% |
