Axsome Therapeutics, Inc. (AXSM) vs Henry Schein, Inc. (HSIC)

A side-by-side comparison of Axsome Therapeutics, Inc. and Henry Schein, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

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Total return — AXSM vs HSIC

growth of $100 · dividends reinvested · last 10y
AXSM +2054.3% (+35.9%/yr)HSIC +33.9% (+3.0%/yr)AXSM compounded faster over this window
Log scale — wide-divergence pair
101001k10kStart $10020182020202220242026$2,154$134
AXSM HSIC

AXSM vs HSIC: by the numbers

  • •HSIC is the larger company ($9.66B vs $8.97B market cap).
  • •HSIC is profitable (2.96% net margin) while AXSM runs a net loss (-24.68%).

Metrics side by side

Valuation

MetricAXSMHSIC
P/E ratioN/A24.73
Forward P/EN/A15.72
PEG ratioN/A7.83
P/S ratio11.550.71
P/B ratio107.703.06
EV / EBITDAN/A12.25
FCF yieldN/A5.58%

Profitability

MetricAXSMHSIC
Gross margin93.24%30.31%
Operating margin-24.28%5.69%
Net margin-24.68%2.96%
ROE-230.05%12.77%
ROIC-50.82%6.53%

Growth (annualized)

MetricAXSMHSIC
Revenue CAGR (5Y)N/A2.71%
EPS CAGR (5Y)N/A3.14%
FCF CAGR (5Y)N/A0.82%
Total return CAGR (5Y)41.40%1.65%

Frequently asked

Is AXSM or HSIC more profitable?
HSIC runs the higher net margin — AXSM at -24.68% versus HSIC at 2.96%.
How have AXSM and HSIC total returns compared?
Over the past 10 years, AXSM delivered 35.76% and HSIC delivered 2.86% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.