Eli Lilly and Company (LLY) vs Mastercard Incorporated (MA)

A side-by-side comparison of Eli Lilly and Company and Mastercard Incorporated across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 11, 2026. Differences are shown without an overall score or investment verdict.

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Different business models: LLY is classified in Healthcare; MA is classified in Financial Services. Margin, capital intensity, and valuation differences should be interpreted in that sector context.

Total returnLLY vs MA

growth of $100 · dividends reinvested · last 10y
LLY +1572.7% (+32.5%/yr)MA +498.8% (+19.6%/yr)LLY compounded faster over this window
05001k2kStart $10020182020202220242026$1,673$599
LLY MA

LLY vs MA: by the numbers

  • LLY is the larger company ($1.05T vs $499.20B market cap).
  • MA trades at the lower trailing earnings multiple (31.31 vs 37.42 P/E), one valuation lens rather than an overall verdict.
  • MA converts more revenue to profit (46.34% vs 33.53% net margin).
  • LLY grew revenue faster over the past five years (24.42% vs 16.09% CAGR).
  • MA pays the higher dividend yield (0.60% vs 0.60%).

Metrics side by side

Valuation

MetricLLYMA
P/E ratio37.4231.31
Forward P/E30.6428.52
P/S ratio13.1814.23
P/B ratio31.0088.97
EV / EBITDA29.91N/A
FCF yield1.91%N/A

Profitability

MetricLLYMA
Gross margin84.01%100.00%
Operating margin43.92%59.84%
Net margin33.53%46.34%
ROE78.84%289.73%
ROIC27.38%N/A

Dividends

MetricLLYMA
Dividend yield0.60%0.60%
Payout ratio22.45%18.54%

Growth (annualized)

MetricLLYMA
Revenue CAGR (5Y)24.42%16.09%
EPS CAGR (5Y)28.88%20.93%
FCF CAGR (5Y)32.91%N/A
Total return CAGR (5Y)37.46%10.88%

Frequently asked

Which has the lower trailing P/E, LLY or MA?
MA has the lower trailing P/E: LLY trades at 37.42 and MA at 31.31. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, LLY or MA?
Over the past five years, LLY grew revenue faster — LLY at a 24.42% CAGR versus MA at 16.09%.
Does LLY or MA pay a bigger dividend?
LLY yields 0.60% and MA yields 0.60% based on trailing dividends and the latest price.
Is LLY or MA more profitable?
MA runs the higher net margin — LLY at 33.53% versus MA at 46.34%.
How have LLY and MA total returns compared?
Over the past 10 years, LLY delivered 32.58% and MA delivered 19.83% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 11, 2026.