Amgen Inc. (AMGN) vs Mastercard Incorporated (MA)
A side-by-side comparison of Amgen Inc. and Mastercard Incorporated across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 10, 2026. Differences are shown without an overall score or investment verdict.
Different business models: AMGN is classified in Healthcare; MA is classified in Financial Services. Margin, capital intensity, and valuation differences should be interpreted in that sector context.
AMGN
Amgen Inc.
$377.35HealthcareDelayed quote: Sep 11, 2026, 4:00 PM EDT
MA
Mastercard Incorporated
$569.19Financial ServicesDelayed quote: Sep 11, 2026, 4:00 PM EDT
Total return — AMGN vs MA
growth of $100 · dividends reinvested · last 10yAMGN +201.9% (+11.7%/yr)MA +498.8% (+19.6%/yr)MA compounded faster over this window
AMGN MA
AMGN vs MA: by the numbers
- •MA is the larger company ($499.20B vs $203.66B market cap).
- •AMGN trades at the lower trailing earnings multiple (23.45 vs 31.31 P/E), one valuation lens rather than an overall verdict.
- •MA converts more revenue to profit (46.34% vs 22.93% net margin).
- •MA grew revenue faster over the past five years (16.09% vs 8.39% CAGR).
- •AMGN pays the higher dividend yield (2.56% vs 0.60%).
Metrics side by side
Valuation
| Metric | AMGN | MA |
|---|---|---|
| P/E ratio | 23.45 | 31.31 |
| Forward P/E | 16.35 | 28.52 |
| P/S ratio | 5.34 | 14.23 |
| P/B ratio | 17.42 | 88.97 |
| FCF yield | 5.00% | N/A |
Profitability
| Metric | AMGN | MA |
|---|---|---|
| Gross margin | 72.65% | 100.00% |
| Operating margin | 33.18% | 59.84% |
| Net margin | 22.93% | 46.34% |
| ROE | 74.80% | 289.73% |
| ROIC | 14.22% | N/A |
Dividends
| Metric | AMGN | MA |
|---|---|---|
| Dividend yield | 2.56% | 0.60% |
| Payout ratio | 60.91% | 18.54% |
Growth (annualized)
| Metric | AMGN | MA |
|---|---|---|
| Revenue CAGR (5Y) | 8.39% | 16.09% |
| EPS CAGR (5Y) | 2.94% | 20.93% |
| FCF CAGR (5Y) | -3.91% | N/A |
| Total return CAGR (5Y) | 15.90% | 10.88% |
Frequently asked
- Which has the lower trailing P/E, AMGN or MA?
- AMGN has the lower trailing P/E: AMGN trades at 23.45 and MA at 31.31. P/E is one valuation measure and does not by itself establish which business is cheaper.
- Which has grown faster, AMGN or MA?
- Over the past five years, MA grew revenue faster — AMGN at a 8.39% CAGR versus MA at 16.09%.
- Does AMGN or MA pay a bigger dividend?
- AMGN yields 2.56% and MA yields 0.60% based on trailing dividends and the latest price.
- Is AMGN or MA more profitable?
- MA runs the higher net margin — AMGN at 22.93% versus MA at 46.34%.
- How have AMGN and MA total returns compared?
- Over the past 10 years, AMGN delivered 11.95% and MA delivered 19.83% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Amgen P/E ratioMastercard P/E ratioAmgen dividend yieldMastercard dividend yieldAmgen ROEMastercard ROEAmgen operating marginMastercard operating marginAmgen revenue growthMastercard revenue growthAmgen free cash flow
Amgen & Mastercard appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 10, 2026.