Amgen Inc. (AMGN) vs Mastercard Incorporated (MA)

A side-by-side comparison of Amgen Inc. and Mastercard Incorporated across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 10, 2026. Differences are shown without an overall score or investment verdict.

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Different business models: AMGN is classified in Healthcare; MA is classified in Financial Services. Margin, capital intensity, and valuation differences should be interpreted in that sector context.

Total returnAMGN vs MA

growth of $100 · dividends reinvested · last 10y
AMGN +201.9% (+11.7%/yr)MA +498.8% (+19.6%/yr)MA compounded faster over this window
200400600Start $10020182020202220242026$302$599
AMGN MA

AMGN vs MA: by the numbers

  • MA is the larger company ($499.20B vs $203.66B market cap).
  • AMGN trades at the lower trailing earnings multiple (23.45 vs 31.31 P/E), one valuation lens rather than an overall verdict.
  • MA converts more revenue to profit (46.34% vs 22.93% net margin).
  • MA grew revenue faster over the past five years (16.09% vs 8.39% CAGR).
  • AMGN pays the higher dividend yield (2.56% vs 0.60%).

Metrics side by side

Valuation

MetricAMGNMA
P/E ratio23.4531.31
Forward P/E16.3528.52
P/S ratio5.3414.23
P/B ratio17.4288.97
FCF yield5.00%N/A

Profitability

MetricAMGNMA
Gross margin72.65%100.00%
Operating margin33.18%59.84%
Net margin22.93%46.34%
ROE74.80%289.73%
ROIC14.22%N/A

Dividends

MetricAMGNMA
Dividend yield2.56%0.60%
Payout ratio60.91%18.54%

Growth (annualized)

MetricAMGNMA
Revenue CAGR (5Y)8.39%16.09%
EPS CAGR (5Y)2.94%20.93%
FCF CAGR (5Y)-3.91%N/A
Total return CAGR (5Y)15.90%10.88%

Frequently asked

Which has the lower trailing P/E, AMGN or MA?
AMGN has the lower trailing P/E: AMGN trades at 23.45 and MA at 31.31. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, AMGN or MA?
Over the past five years, MA grew revenue faster — AMGN at a 8.39% CAGR versus MA at 16.09%.
Does AMGN or MA pay a bigger dividend?
AMGN yields 2.56% and MA yields 0.60% based on trailing dividends and the latest price.
Is AMGN or MA more profitable?
MA runs the higher net margin — AMGN at 22.93% versus MA at 46.34%.
How have AMGN and MA total returns compared?
Over the past 10 years, AMGN delivered 11.95% and MA delivered 19.83% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 10, 2026.