Basis: Trailing twelve months (TTM), to the latest fiscal quarter end. Source: stored company filings and market data; unavailable inputs remain N/A.
Is the return on invested capital (ROIC) high or low?
The return on invested capital (ROIC) of -497.29% is 435% below its 5-year average of -92.90%, near the low end of its 5-year range (-497.29%–-12.63%).
As of the fiscal period ended Tuesday, June 30, 2026. 130.10% below its 12-month average of -216.12%.
Trailing-twelve-month return on invested capital at each fiscal quarter end; no daily interpolation. Q2 FY2026 (2026-06-30): -497.29%.
RETURN ON INVESTED CAPITAL (ROIC)
-497.29%
RETURN ON INVESTED CAPITAL (ROIC) AVG TTM
-216.12%
RETURN ON INVESTED CAPITAL (ROIC) AVG 3Y
-118.25%
RETURN ON INVESTED CAPITAL (ROIC) AVG 5Y
-92.90%
RETURN ON INVESTED CAPITAL (ROIC) AVG 10Y
-80.36%
RETURN ON INVESTED CAPITAL (ROIC) AVG 15Y
-73.47%
RETURN ON INVESTED CAPITAL (ROIC) AVG 20Y
N/A
CURRENT VS TTM AVG
-130.10%
CURRENT VS 3Y AVG
-320.54%
CURRENT VS 5Y AVG
-435.30%
CURRENT VS 10Y AVG
-518.84%
CURRENT VS 15Y AVG
-576.83%
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
-33.73%
median of 743 covered companies
CURRENT VS SECTOR MEDIAN
-1374.34%
vs the sector median at left
Cocrystal Pharma, Inc.
Market Cap
$15.42M
Return on Invested Capital (ROIC)
-497.29%
TTM Avg
-216.12%
3Y Avg
-118.25%
5Y Avg
-92.90%
Market Cap
$15.78M
Return on Invested Capital (ROIC)
-273.70%
TTM Avg
-707.06%
3Y Avg
-535.27%
5Y Avg
-358.40%
Market Cap
$15.72M
Return on Invested Capital (ROIC)
-41.81%
TTM Avg
-159.62%
3Y Avg
-298.97%
5Y Avg
-203.41%
Market Cap
$15.83M
Return on Invested Capital (ROIC)
N/A
TTM Avg
-183.21%
3Y Avg
-122.71%
5Y Avg
-100.21%
Market Cap
$14.97M
Return on Invested Capital (ROIC)
-48.04%
TTM Avg
-66.55%
3Y Avg
-57.55%
5Y Avg
-44.03%
Market Cap
$14.57M
Return on Invested Capital (ROIC)
-13.15%
TTM Avg
-23.00%
3Y Avg
-25.06%
5Y Avg
-54.51%
Market Cap
$16.40M
Return on Invested Capital (ROIC)
-279.48%
TTM Avg
-96.52%
3Y Avg
-105.30%
5Y Avg
-89.17%
Market Cap
$16.64M
Return on Invested Capital (ROIC)
-85.72%
TTM Avg
-120.02%
3Y Avg
-101.35%
5Y Avg
-83.66%
Market Cap
$14.09M
Return on Invested Capital (ROIC)
N/A
TTM Avg
N/A
3Y Avg
N/A
5Y Avg
N/A
| NAME | MARKET CAP | RETURN ON INVESTED CAPITAL (ROIC) | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Cocrystal Pharma, Inc. (COCP) | $15.42M | -497.29% | -216.12% | -118.25% | -92.90% |
| BioCardia, Inc. (BCDA)vs › | $15.78M | -273.70% | -707.06% | -535.27% | -358.40% |
| Allarity Therapeutics, Inc. (ALLR)vs › | $15.72M | -41.81% | -159.62% | -298.97% | -203.41% |
| Karyopharm Therapeutics Inc. (KPTI)vs › | $15.83M | N/A | -183.21% | -122.71% | -100.21% |
| Pasithea Therapeutics Corp. (KTTA)vs › | $14.97M | -48.04% | -66.55% | -57.55% | -44.03% |
| Pulsenmore Ltd. Ordinary Shares (PLSM)vs › | $14.57M | -13.15% | -23.00% | -25.06% | -54.51% |
| Dyadic International, Inc. (DYAI)vs › | $16.40M | -279.48% | -96.52% | -105.30% | -89.17% |
| Bionano Genomics, Inc. (BNGO)vs › | $16.64M | -85.72% | -120.02% | -101.35% | -83.66% |
| Obsidian Therapeutics Inc. (OBX)vs › | $14.09M | N/A | N/A | N/A | N/A |
| Palatin Technologies, Inc. (PTN)vs › | $16.76M | -125.44% | -125.44% | -1118.57% | -719.84% |
ROIC
-497.3%
ROE
-951.9%
ROIC = NOPAT / Invested Capital, where NOPAT = Operating Income × (1 − effective tax rate) and Invested Capital = Total Assets − (Current Liabilities − Short-Term Debt)
Return on invested capital measures the after-tax operating return a company earns on the capital invested in the business. TGMCharts computes it from reported statements: trailing-twelve-month operating income after tax, over invested capital at the latest balance sheet — total assets less the non-interest-bearing current liabilities (payables, accruals, deferred revenue) that fund them; short-term debt stays in the capital base. The tax rate is the period's own effective rate (income tax ÷ pretax income), capped at 45%; when pretax income is zero or negative, or the tax line is a net benefit, no tax is deducted — the operating figure is shown untaxed rather than adjusted by an assumed rate. Not shown for banks, insurers or funds.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | RETURN ON INVESTED CAPITAL (ROIC) |
|---|---|
| 2026-06-30 | -497.29% |
| 2026-03-31 | -163.07% |
| 2025-12-31 | -120.22% |
| 2025-09-30 | -109.43% |
| 2025-06-30 | -190.61% |
| 2025-03-31 | -184.02% |
| 2024-12-31 | -162.11% |
| 2024-09-30 | -135.20% |
| 2024-06-30 | -98.92% |
| 2024-03-31 | -72.85% |
| 2023-12-31 | -66.29% |
| 2023-09-30 | -59.94% |
| 2023-06-30 | -56.36% |
| 2023-03-31 | -114.52% |
| 2022-12-31 | -97.99% |
| 2022-09-30 | -86.37% |
| 2022-06-30 | -73.21% |
| 2022-03-31 | -21.25% |
| 2021-12-31 | -18.27% |
| 2021-09-30 | -14.73% |
| 2021-06-30 | -12.63% |
| 2021-03-31 | -19.78% |
| 2020-12-31 | -18.13% |
| 2020-09-30 | -110.76% |
| 2020-06-30 | -146.91% |
| 2020-03-31 | -130.13% |
| 2019-12-31 | -184.44% |
| 2019-09-30 | -79.61% |
| 2019-06-30 | -78.57% |
| 2019-03-31 | -77.78% |
| 2018-12-31 | -93.90% |
| 2018-09-30 | -6.87% |
| 2018-06-30 | -6.50% |
| 2018-03-31 | -6.04% |
| 2017-12-31 | -6.88% |
| 2017-09-30 | -83.67% |
| 2017-06-30 | -82.10% |
| 2017-03-31 | -85.98% |
| 2016-12-31 | -86.14% |
| 2016-09-30 | -25.63% |
| 2016-06-30 | -26.53% |
| 2016-03-31 | -26.05% |
| 2015-12-31 | -24.80% |
| 2015-09-30 | -4.29% |
| 2015-06-30 | -3.39% |
| 2015-03-31 | -2.53% |
| 2014-12-31 | -2.32% |
| 2014-09-30 | -128.40% |
| 2014-06-30 | -70.91% |
| 2013-06-30 | -375.96% |
| 2013-03-31 | -299.68% |
| 2012-12-31 | -127.50% |
| 2012-09-30 | -17.55% |
| 2012-06-30 | -208.11% |
| 2011-12-31 | -94.04% |
| 2011-09-30 | -38.15% |
| 2011-06-30 | -5.23% |
| 2010-12-31 | -1.27% |
| 2010-09-30 | -338.06% |
| 2010-06-30 | -135.91% |
| 2010-03-31 | -56.30% |
| 2009-12-31 | -78.56% |
| 2009-09-30 | -63.21% |
| 2009-06-30 | -60.79% |
| 2009-03-31 | -65.36% |
| 2008-12-31 | -58.58% |
| 2008-09-30 | -69.14% |
| 2008-06-30 | -82.26% |
