Xenon Pharmaceuticals (XENE) Metrics: History & Chart

Xenon Pharmaceuticals Inc.(XENE)

Biotechnology · Burnaby, BC

$36.35-1.22 (-3.25%)

Delayed quote: Oct 6, 2026, 3:05 PM EDT

About Xenon Pharmaceuticals Inc.

Xenon Pharmaceuticals Inc. is a clinical-stage biopharmaceutical company dedicated to discovering and advancing innovative treatments for individuals living with neurological disorders. The company operates primarily from its headquarters in Burnaby, Canada. Its robust clinical pipeline showcases several promising candidates: XEN496, an activator of Kv7 potassium channels, is currently in Phase III clinical trials for KCNQ2 developmental and epileptic encephalopathy. Another Kv7 potassium channel activator, XEN1101, is progressing through Phase II trials, targeting epilepsy and a range of other neurological conditions. The portfolio also includes NBI-921352, a selective inhibitor of the Nav1.6 sodium channel, which is undergoing Phase II clinical evaluation for SCN8A developmental and epileptic encephalopathy, alongside investigations for adult focal epilepsy and other potential indications. Furthermore, XEN007, a central nervous system-acting calcium channel modulator, is also in Phase II development. Beyond its internal development, Xenon Pharmaceuticals has established strategic collaborations. This includes a licensing and development agreement with Neurocrine Biosciences, Inc. focused on epilepsy treatments, and a partnership with Flexion Therapeutics, Inc. to advance PCRX301 (also known as XEN402), a Nav1.7 inhibitor, for post-operative pain management. Established in 1996, the company continues its mission to address significant unmet medical needs in neurology.

Burnaby, BC

364 employees

www.xenon-pharma.com

Healthcare / Biotechnology

Sector: Healthcare
Industry: Biotechnology
CEO: Ian C. Mortimer

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Third-Party DCF Estimate (FMP)	N/A
Price Gap vs Third-Party Estimate	N/A

7D Total Return	+2.31%
30D Total Return	-37.12%
YTD Total Return	-16.18%
1Y Total Return	-5.15%
3Y Total Return	+6.81%
5Y Total Return	+25.27%
10Y Total Return	+383.46%
15Y Total Return	N/A
20Y Total Return	N/A

2026	-16.18%
2025	+14.34%
2024	-14.89%
2023	+16.81%
2022	+26.22%
2021	+103.12%
2020

CAGR TTM	-5.13%
CAGR 3Y	+2.22%
CAGR 5Y	+4.61%
CAGR 10Y	+17.07%
CAGR 15Y	N/A
CAGR 20Y	N/A

PE Ratio	64.68
PE Ratio Avg TTM	45.59
PE Ratio Avg 3Y	45.17
Current VS TTM Avg	+41.88%
Current VS 3Y Avg	+43.18%
Current VS 5Y Avg	+43.18%

All Metrics

XENE Valuation Metrics

XENE Stock Price Metrics

XENE Dividend Metrics

XENE Growth Rate Metrics

XENE Discounted Cash Flow Metrics

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XENE Yearly Returns

XENE Average Annual Returns By Period (CAGR)

XENE Revenue Metrics

XENE PE Ratio Metrics

XENE PS Ratio Metrics

XENE PB Ratio Metrics

XENE Price to Free Cash Flow Ratio Metrics

XENE Debt to Equity Ratio Metrics

XENE PEG Ratio Metrics

XENE FCF Yield

XENE Earnings Yield

XENE EBITDA Yield

XENE OCF Yield

XENE EV/EBIT Ratio Metrics

XENE EV/EBITDA Ratio Metrics

XENE EV/Assets Ratio Metrics

XENE EV/Sales Ratio Metrics

XENE Current Ratio Metrics

XENE Quick Ratio Metrics

XENE ROIC Metrics

XENE Return on Assets Metrics

XENE Return on Equity Metrics

XENE Net Profit Margin Metrics

XENE Gross Profit Margin Metrics

XENE Tax Rate Metrics

PS Ratio	591.76
PS Ratio Avg TTM	422.56
PS Ratio Avg 3Y	1127.45
Current VS TTM Avg	+40.04%
Current VS 3Y Avg	-47.51%
Current VS 5Y Avg	+181.01%

PB Ratio	3.01
PB Ratio Avg TTM	5.42
PB Ratio Avg 3Y	4.13
Current VS TTM Avg	-44.42%
Current VS 3Y Avg	-27.14%
Current VS 5Y Avg	-22.89%

PFCF Ratio	N/A
PFCF Ratio Avg TTM	N/A
PFCF Ratio Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

Debt/Equity Ratio	0.01
Debt/Equity Ratio Avg TTM	0.01
Debt/Equity Ratio Avg 3Y	0.01
Current VS TTM Avg	-51.31%
Current VS 3Y Avg	-59.29%
Current VS 5Y Avg	-61.81%

PEG Ratio	N/A
PEG Ratio Avg TTM	N/A
PEG Ratio Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

FCF Yield	N/A
FCF Yield Avg TTM	N/A
FCF Yield Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

Earnings Yield	1.55%
Earnings Yield Avg TTM	3.01%
Earnings Yield Avg 3Y	3.03%
Current VS TTM Avg	-48.50%
Current VS 3Y Avg	-48.89%
Current VS 5Y Avg	-48.89%

EBITDA Yield	N/A
EBITDA Yield Avg TTM	N/A
EBITDA Yield Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

OCF Yield	N/A
OCF Yield Avg TTM	N/A
OCF Yield Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

Ev/Ebit Ratio	7.67
Ev/Ebit Ratio Avg TTM	12.29
Ev/Ebit Ratio Avg 3Y	12.23
Current VS TTM Avg	-37.59%
Current VS 3Y Avg	-37.31%
Current VS 5Y Avg	-37.31%

Ev/Ebitda Ratio	6.88
Ev/Ebitda Ratio Avg TTM	11.43
Ev/Ebitda Ratio Avg 3Y	11.37
Current VS TTM Avg	-39.78%
Current VS 3Y Avg	-39.51%
Current VS 5Y Avg	-39.51%

Ev/Assets Ratio	2.80
Ev/Assets Ratio Avg TTM	4.37
Ev/Assets Ratio Avg 3Y	3.78
Current VS TTM Avg	-35.93%
Current VS 3Y Avg	-25.98%
Current VS 5Y Avg	-20.90%

Ev/Sales Ratio	566.27
Ev/Sales Ratio Avg TTM	414.79
Ev/Sales Ratio Avg 3Y	1096.75
Current VS TTM Avg	+36.52%
Current VS 3Y Avg	-48.37%
Current VS 5Y Avg	+182.35%

Current Ratio	21.02
Current Ratio Avg TTM	17.98
Current Ratio Avg 3Y	19.61
Current VS TTM Avg	+16.90%
Current VS 3Y Avg	+7.16%
Current VS 5Y Avg	-8.39%

Quick Ratio	21.02
Quick Ratio Avg TTM	17.98
Quick Ratio Avg 3Y	19.61
Current VS TTM Avg	+16.90%
Current VS 3Y Avg	+7.16%
Current VS 5Y Avg	-8.39%

ROIC	(35.27%)
ROIC Avg 3Y	(33.35%)
ROIC Avg 5Y	(27.28%)
Current VS 3Y Avg	-5.75%
Current VS 5Y Avg	-29.29%
Current VS 10Y Avg	-14.25%

ROA	(31.58%)
ROA Avg TTM	(10.83%)
ROA Avg 3Y	(7.43%)
Current VS TTM Avg	-191.53%
Current VS 3Y Avg	-325.22%
Current VS 5Y Avg	-365.97%

ROE	(32.94%)
ROE Avg TTM	(43.93%)
ROE Avg 3Y	(28.75%)
Current VS TTM Avg	+25.02%
Current VS 3Y Avg	-14.56%
Current VS 5Y Avg	-35.81%

Net Profit Margin	(4612.13%)
Net Profit Margin Avg TTM	0.00%
Net Profit Margin Avg 3Y	0.00%
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	-17702.92%

Gross Profit Margin	66.09%
Gross Pft Margin Avg TTM	0.00%
Gross Pft Margin Avg 3Y	0.00%
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	+832.48%

Tax Rate	199.87%
Tax Rate Avg 3Y	99.99%
Tax Rate Avg 5Y	99.99%
Current VS 3Y Avg	+99.89%
Current VS 5Y Avg	+99.89%
Current VS 10Y Avg	+448.91%