Basis: Trailing twelve months (TTM), to the latest fiscal quarter end. Source: stored company filings and market data; unavailable inputs remain N/A.
Is the return on equity (ROE) high or low?
The return on equity (ROE) of -104.65% is 21% above its 4-year average of -133.22%, near the low end of its 4-year range (-256.81%–338.98%).
As of the fiscal period ended Tuesday, June 30, 2026. 4.47% below its 12-month average of -100.17%.
Trailing-twelve-month return on equity at each fiscal quarter end; no daily interpolation. Q2 FY2026 (2026-06-30): -104.65%.
RETURN ON EQUITY (ROE)
-104.65%
RETURN ON EQUITY (ROE) AVG TTM
-100.17%
RETURN ON EQUITY (ROE) AVG 3Y
-133.22%
RETURN ON EQUITY (ROE) AVG 5Y
-133.22%
RETURN ON EQUITY (ROE) AVG 10Y
-138.28%
RETURN ON EQUITY (ROE) AVG 15Y
-108.39%
RETURN ON EQUITY (ROE) AVG 20Y
N/A
CURRENT VS TTM AVG
-4.47%
CURRENT VS 3Y AVG
+21.44%
CURRENT VS 5Y AVG
+21.44%
CURRENT VS 10Y AVG
+24.32%
CURRENT VS 15Y AVG
+3.45%
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
-42.01%
median of 754 covered companies
CURRENT VS SECTOR MEDIAN
-149.11%
vs the sector median at left
Talphera, Inc.
Market Cap
$57.09M
Return on Equity (ROE)
-104.65%
TTM Avg
-100.17%
3Y Avg
-133.22%
5Y Avg
-133.22%
Market Cap
$56.98M
Return on Equity (ROE)
-72.55%
TTM Avg
6.13%
3Y Avg
236.20%
5Y Avg
116.25%
Market Cap
$57.88M
Return on Equity (ROE)
N/A
TTM Avg
-285.38%
3Y Avg
-206.98%
5Y Avg
-151.57%
Market Cap
$58.29M
Return on Equity (ROE)
N/A
TTM Avg
71.44%
3Y Avg
1810.59%
5Y Avg
1190.90%
Market Cap
$58.32M
Return on Equity (ROE)
-58.99%
TTM Avg
-51.19%
3Y Avg
-1.82%
5Y Avg
11.74%
Market Cap
$58.73M
Return on Equity (ROE)
-132.16%
TTM Avg
-74.56%
3Y Avg
-71.32%
5Y Avg
22.85%
Market Cap
$59.33M
Return on Equity (ROE)
-82.38%
TTM Avg
-68.06%
3Y Avg
-60.95%
5Y Avg
-49.61%
Market Cap
$59.64M
Return on Equity (ROE)
N/A
TTM Avg
85.37%
3Y Avg
6.44%
5Y Avg
-23.00%
Market Cap
$60.03M
Return on Equity (ROE)
-30.21%
TTM Avg
-215.14%
3Y Avg
-180.32%
5Y Avg
47.11%
| NAME | MARKET CAP | RETURN ON EQUITY (ROE) | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Talphera, Inc. (TLPH) | $57.09M | -104.65% | -100.17% | -133.22% | -133.22% |
| OKYO Pharma Limited (OKYO)vs › | $56.98M | -72.55% | 6.13% | 236.20% | 116.25% |
| PDS Biotechnology Corporation (PDSB)vs › | $57.88M | N/A | -285.38% | -206.98% | -151.57% |
| MiNK Therapeutics, Inc. (INKT)vs › | $58.29M | N/A | 71.44% | 1810.59% | 1190.90% |
| Boundless Bio, Inc. (BOLD)vs › | $58.32M | -58.99% | -51.19% | -1.82% | 11.74% |
| Connect Biopharma Holdings Limited (CNTB)vs › | $58.73M | -132.16% | -74.56% | -71.32% | 22.85% |
| Adicet Bio, Inc. (ACET)vs › | $59.33M | -82.38% | -68.06% | -60.95% | -49.61% |
| Oncolytics Biotech Inc. (ONCY)vs › | $59.64M | N/A | 85.37% | 6.44% | -23.00% |
| Xilio Therapeutics, Inc. (XLO)vs › | $60.03M | -30.21% | -215.14% | -180.32% | 47.11% |
| Rani Therapeutics Holdings, Inc. (RANI)vs › | $53.73M | -76.82% | -798.41% | -485.96% | -324.45% |
ROE
-104.7%
ROA
-56.2%
ROE = Net Income / Total Shareholders' Equity
Return on equity measures how efficiently a company generates profit from shareholders' equity. Higher ROE indicates better capital efficiency.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | RETURN ON EQUITY (ROE) |
|---|---|
| 2026-06-30 | -104.65% |
| 2026-03-31 | -77.13% |
| 2025-12-31 | -83.89% |
| 2025-09-30 | -64.60% |
| 2025-06-30 | -170.59% |
| 2025-03-31 | -207.95% |
| 2024-12-31 | -162.53% |
| 2024-09-30 | -162.34% |
| 2024-06-30 | -107.27% |
| 2024-03-31 | -86.93% |
| 2023-12-31 | -130.43% |
| 2023-09-30 | -116.70% |
| 2023-06-30 | -256.81% |
| 2023-03-31 | 338.98% |
| 2022-12-31 | 218.92% |
| 2022-09-30 | 171.82% |
| 2022-06-30 | 137.88% |
| 2016-06-30 | -204.10% |
| 2016-03-31 | -108.15% |
| 2015-12-31 | -73.68% |
| 2015-09-30 | -69.24% |
| 2015-06-30 | -96.04% |
| 2015-03-31 | -82.14% |
| 2014-12-31 | -71.49% |
| 2014-09-30 | -2.99% |
| 2014-06-30 | -24.16% |
| 2014-03-31 | -31.19% |
| 2013-12-31 | -32.02% |
| 2013-09-30 | -97.20% |
| 2013-06-30 | -816.31% |
| 2013-03-31 | -178.17% |
| 2012-12-31 | -98.57% |
| 2012-06-30 | -345.99% |
| 2012-03-31 | -217.22% |
| 2011-12-31 | -115.07% |
| 2011-09-30 | -73.86% |
| 2011-06-30 | -53.11% |
| 2011-03-31 | -43.39% |
| 2010-09-30 | -644.30% |
