Talphera (TLPH) Metrics: History & Chart

Talphera, Inc.(TLPH)

Drug Manufacturers - Specialty & Generic · San Mateo, CA

$1.11-0.05 (-4.31%)

Delayed quote: Oct 6, 2026, 4:00 PM EDT

About Talphera, Inc.

Talphera, Inc. is a specialty pharmaceutical company focused on developing and commercializing therapeutic products intended for use in carefully monitored medical environments. Their lead experimental candidate is Niyad, a lyophilized (freeze-dried) formulation of nafamostat. This anticoagulant is currently being assessed under an investigational device exemption for its application in extracorporeal circuits. The company's development pipeline also features LTX-608, a potential anti-inflammatory and antiviral agent being explored for the treatment of numerous conditions, including COVID-19, disseminated intravascular coagulation (DIC), acute respiratory distress syndrome (ARDS), and acute pancreatitis. Furthermore, Talphera is advancing Fedsyra, a pre-filled syringe containing ephedrine, and PFS-02, a pre-filled syringe containing phenylephrine. Established in 2005, the company was previously known as AcelRx Pharmaceuticals, Inc. It adopted the name Talphera, Inc. in January 2024 and maintains its corporate headquarters in San Mateo, California.

San Mateo, CA

12 employees

talphera.com

Healthcare / Drug Manufacturers - Specialty & Generic

Sector: Healthcare
Industry: Drug Manufacturers - Specialty & Generic
CEO: Vincent J. Angotti

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Third-Party DCF Estimate (FMP)	N/A
Price Gap vs Third-Party Estimate	N/A

7D Total Return	-2.52%
30D Total Return	-3.33%
YTD Total Return	+1.75%
1Y Total Return	+22.11%
3Y Total Return	+100.02%
5Y Total Return	-94.32%
10Y Total Return	-98.48%
15Y Total Return	-98.10%
20Y Total Return	N/A

2026	+1.75%
2025	+117.52%
2024	-29.18%
2023	-67.26%
2022	-79.82%
2021	-54.84%
2020

CAGR TTM	+21.99%
CAGR 3Y	+25.99%
CAGR 5Y	-43.65%
CAGR 10Y	-34.23%
CAGR 15Y	-23.21%
CAGR 20Y	N/A

PE Ratio	0.14
PE Ratio Avg TTM	0.43
PE Ratio Avg 3Y	0.43
Current VS TTM Avg	-67.63%
Current VS 3Y Avg	-67.63%
Current VS 5Y Avg	-67.63%

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TLPH Valuation Metrics

TLPH Stock Price Metrics

TLPH Dividend Metrics

TLPH Growth Rate Metrics

TLPH Discounted Cash Flow Metrics

TLPH Returns By Period

TLPH Yearly Returns

TLPH Average Annual Returns By Period (CAGR)

TLPH Revenue Metrics

TLPH PE Ratio Metrics

TLPH PS Ratio Metrics

TLPH PB Ratio Metrics

TLPH Price to Free Cash Flow Ratio Metrics

TLPH Debt to Equity Ratio Metrics

TLPH PEG Ratio Metrics

TLPH FCF Yield

TLPH Earnings Yield

TLPH EBITDA Yield

TLPH OCF Yield

TLPH EV/EBIT Ratio Metrics

TLPH EV/EBITDA Ratio Metrics

TLPH EV/Assets Ratio Metrics

TLPH EV/Sales Ratio Metrics

TLPH Current Ratio Metrics

TLPH Quick Ratio Metrics

TLPH ROIC Metrics

TLPH Return on Assets Metrics

TLPH Return on Equity Metrics

TLPH Net Profit Margin Metrics

TLPH Gross Profit Margin Metrics

TLPH Tax Rate Metrics

PS Ratio	87611.20
PS Ratio Avg TTM	25671.29
PS Ratio Avg 3Y	481.35
Current VS TTM Avg	+241.28%
Current VS 3Y Avg	+18101.33%
Current VS 5Y Avg	+100176.92%

PB Ratio	6.08
PB Ratio Avg TTM	3.32
PB Ratio Avg 3Y	1.79
Current VS TTM Avg	+82.88%
Current VS 3Y Avg	+240.41%
Current VS 5Y Avg	+311.68%

PFCF Ratio	N/A
PFCF Ratio Avg TTM	N/A
PFCF Ratio Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

Debt/Equity Ratio	0.00
Debt/Equity Ratio Avg TTM	0.34
Debt/Equity Ratio Avg 3Y	0.40
Current VS TTM Avg	-100.00%
Current VS 3Y Avg	-100.00%
Current VS 5Y Avg	-100.00%

PEG Ratio	N/A
PEG Ratio Avg TTM	N/A
PEG Ratio Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

FCF Yield	N/A
FCF Yield Avg TTM	N/A
FCF Yield Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

Earnings Yield	690.62%
Earnings Yield Avg TTM	441.57%
Earnings Yield Avg 3Y	441.57%
Current VS TTM Avg	+56.40%
Current VS 3Y Avg	+56.40%
Current VS 5Y Avg	+56.40%

EBITDA Yield	N/A
EBITDA Yield Avg TTM	N/A
EBITDA Yield Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

OCF Yield	N/A
OCF Yield Avg TTM	N/A
OCF Yield Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

Ev/Ebit Ratio	N/A
Ev/Ebit Ratio Avg TTM	N/A
Ev/Ebit Ratio Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

Ev/Ebitda Ratio	N/A
Ev/Ebitda Ratio Avg TTM	N/A
Ev/Ebitda Ratio Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

Ev/Assets Ratio	3.24
Ev/Assets Ratio Avg TTM	1.82
Ev/Assets Ratio Avg 3Y	0.95
Current VS TTM Avg	+78.46%
Current VS 3Y Avg	+239.44%
Current VS 5Y Avg	+318.89%

Ev/Sales Ratio	86869.20
Ev/Sales Ratio Avg TTM	24657.57
Ev/Sales Ratio Avg 3Y	540.89
Current VS TTM Avg	+252.30%
Current VS 3Y Avg	+15960.39%
Current VS 5Y Avg	+37160.36%

Current Ratio	4.29
Current Ratio Avg TTM	4.97
Current Ratio Avg 3Y	4.27
Current VS TTM Avg	-13.53%
Current VS 3Y Avg	+0.66%
Current VS 5Y Avg	+20.87%

Quick Ratio	4.29
Quick Ratio Avg TTM	4.97
Quick Ratio Avg 3Y	4.27
Current VS TTM Avg	-13.53%
Current VS 3Y Avg	+0.66%
Current VS 5Y Avg	+21.68%

ROIC	(65.20%)
ROIC Avg 3Y	(85.65%)
ROIC Avg 5Y	(78.42%)
Current VS 3Y Avg	+23.88%
Current VS 5Y Avg	+16.85%
Current VS 10Y Avg	-6.29%

ROA	(56.24%)
ROA Avg TTM	(14.56%)
ROA Avg 3Y	(14.45%)
Current VS TTM Avg	-286.21%
Current VS 3Y Avg	-289.13%
Current VS 5Y Avg	-305.98%

ROE	(104.65%)
ROE Avg TTM	(100.17%)
ROE Avg 3Y	(133.22%)
Current VS TTM Avg	-4.47%
Current VS 3Y Avg	+21.44%
Current VS 5Y Avg	+21.44%

Net Profit Margin	(1507600.00%)
Net Profit Margin Avg TTM	(88720.00%)
Net Profit Margin Avg 3Y	(408.63%)
Current VS TTM Avg	-1599.28%
Current VS 3Y Avg	-368836.80%
Current VS 5Y Avg	-252695.86%

Gross Profit Margin	100.00%
Gross Pft Margin Avg TTM	20.00%
Gross Pft Margin Avg 3Y	(154.15%)
Current VS TTM Avg	+400.00%
Current VS 3Y Avg	+164.87%
Current VS 5Y Avg	+2430.84%

Tax Rate	0.00%
Tax Rate Avg 3Y	0.00%
Tax Rate Avg 5Y	0.00%
Current VS 3Y Avg	-100.00%
Current VS 5Y Avg	-100.00%
Current VS 10Y Avg	-100.00%