Basis: Trailing twelve months (TTM), to the latest fiscal quarter end. Source: stored company filings and market data; unavailable inputs remain N/A.
Is the return on invested capital (ROIC) high or low?
The return on invested capital (ROIC) of -33.10% is 106% below its 5-year average of -16.09%, around the middle of its 5-year range (-68.04%–16.90%).
As of the fiscal period ended Tuesday, June 30, 2026. 13.88% below its 12-month average of -29.07%.
Trailing-twelve-month return on invested capital at each fiscal quarter end; no daily interpolation. Q2 FY2026 (2026-06-30): -33.10%.
RETURN ON INVESTED CAPITAL (ROIC)
-33.10%
RETURN ON INVESTED CAPITAL (ROIC) AVG TTM
-29.07%
RETURN ON INVESTED CAPITAL (ROIC) AVG 3Y
-25.06%
RETURN ON INVESTED CAPITAL (ROIC) AVG 5Y
-16.09%
RETURN ON INVESTED CAPITAL (ROIC) AVG 10Y
-39.92%
RETURN ON INVESTED CAPITAL (ROIC) AVG 15Y
N/A
RETURN ON INVESTED CAPITAL (ROIC) AVG 20Y
N/A
CURRENT VS TTM AVG
-13.88%
CURRENT VS 3Y AVG
-32.10%
CURRENT VS 5Y AVG
-105.69%
CURRENT VS 10Y AVG
+17.09%
CURRENT VS 15Y AVG
N/A
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
-34.77%
median of 755 covered companies
CURRENT VS SECTOR MEDIAN
+4.81%
vs the sector median at left
Cartesian Therapeutics, Inc.
Market Cap
$208.55M
Return on Invested Capital (ROIC)
-33.10%
TTM Avg
-29.07%
3Y Avg
-25.06%
5Y Avg
-16.09%
Market Cap
$208.59M
Return on Invested Capital (ROIC)
-40.18%
TTM Avg
-34.28%
3Y Avg
-58.87%
5Y Avg
-58.87%
Market Cap
$211.33M
Return on Invested Capital (ROIC)
26.14%
TTM Avg
3.79%
3Y Avg
-12.27%
5Y Avg
-17.37%
Market Cap
$205.95M
Return on Invested Capital (ROIC)
14.99%
TTM Avg
15.04%
3Y Avg
13.17%
5Y Avg
12.12%
Market Cap
$206.08M
Return on Invested Capital (ROIC)
N/A
TTM Avg
N/A
3Y Avg
N/A
5Y Avg
N/A
Market Cap
$213.72M
Return on Invested Capital (ROIC)
-71.04%
TTM Avg
-53.65%
3Y Avg
-40.34%
5Y Avg
-35.55%
Market Cap
$213.50M
Return on Invested Capital (ROIC)
-43.74%
TTM Avg
-105.81%
3Y Avg
-81.36%
5Y Avg
-65.49%
Market Cap
$213.71M
Return on Invested Capital (ROIC)
8.84%
TTM Avg
15.21%
3Y Avg
-9.34%
5Y Avg
-32.56%
Market Cap
$216.34M
Return on Invested Capital (ROIC)
19.13%
TTM Avg
15.37%
3Y Avg
31.31%
5Y Avg
44.42%
| NAME | MARKET CAP | RETURN ON INVESTED CAPITAL (ROIC) | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Cartesian Therapeutics, Inc. (RNAC) | $208.55M | -33.10% | -29.07% | -25.06% | -16.09% |
| Sionna Therapeutics, Inc. (SION)vs › | $208.59M | -40.18% | -34.28% | -58.87% | -58.87% |
| Compugen Ltd. (CGEN)vs › | $211.33M | 26.14% | 3.79% | -12.27% | -17.37% |
| Pro-Dex, Inc. (PDEX)vs › | $205.95M | 14.99% | 15.04% | 13.17% | 12.12% |
| Electra Therapeutics Inc. (ETRA)vs › | $206.08M | N/A | N/A | N/A | N/A |
| Alector, Inc. (ALEC)vs › | $213.72M | -71.04% | -53.65% | -40.34% | -35.55% |
| Prelude Therapeutics Incorporated (PRLD)vs › | $213.50M | -43.74% | -105.81% | -81.36% | -65.49% |
| Niagen Bioscience Inc (NAGE)vs › | $213.71M | 8.84% | 15.21% | -9.34% | -32.56% |
| Anbio Biotechnology Class A Ordinary Shares (NNNN)vs › | $216.34M | 19.13% | 15.37% | 31.31% | 44.42% |
| Surrozen, Inc. (SRZN)vs › | $196.96M | -41.61% | -54.73% | -70.67% | -64.43% |
ROIC
-33.1%
ROE
N/A
ROIC = NOPAT / Invested Capital, where NOPAT = Operating Income × (1 − effective tax rate) and Invested Capital = Total Assets − (Current Liabilities − Short-Term Debt)
Return on invested capital measures the after-tax operating return a company earns on the capital invested in the business. TGMCharts computes it from reported statements: trailing-twelve-month operating income after tax, over invested capital at the latest balance sheet — total assets less the non-interest-bearing current liabilities (payables, accruals, deferred revenue) that fund them; short-term debt stays in the capital base. The tax rate is the period's own effective rate (income tax ÷ pretax income), capped at 45%; when pretax income is zero or negative, or the tax line is a net benefit, no tax is deducted — the operating figure is shown untaxed rather than adjusted by an assumed rate. Not shown for banks, insurers or funds.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | RETURN ON INVESTED CAPITAL (ROIC) |
|---|---|
| 2026-06-30 | -33.10% |
| 2026-03-31 | -33.01% |
| 2025-12-31 | -30.36% |
| 2025-09-30 | -25.50% |
| 2025-06-30 | -23.37% |
| 2025-03-31 | -13.30% |
| 2024-12-31 | -10.65% |
| 2024-09-30 | -12.33% |
| 2024-06-30 | -15.23% |
| 2024-03-31 | -28.20% |
| 2023-12-31 | -36.49% |
| 2023-09-30 | -68.04% |
| 2023-06-30 | -39.14% |
| 2023-03-31 | -10.49% |
| 2022-12-31 | 9.74% |
| 2022-09-30 | 16.90% |
| 2022-06-30 | 11.29% |
| 2022-03-31 | 7.89% |
| 2021-12-31 | -4.91% |
| 2021-09-30 | -21.90% |
| 2021-06-30 | -29.67% |
| 2021-03-31 | -48.77% |
| 2020-12-31 | -67.73% |
| 2020-09-30 | -59.13% |
| 2020-06-30 | -97.50% |
| 2020-03-31 | -78.60% |
| 2019-12-31 | -62.80% |
| 2019-09-30 | -175.47% |
| 2019-06-30 | -159.98% |
| 2019-03-31 | -119.97% |
| 2018-12-31 | -211.64% |
| 2018-09-30 | -148.54% |
| 2018-06-30 | -113.72% |
| 2018-03-31 | -82.96% |
| 2017-12-31 | -70.77% |
| 2017-09-30 | -59.32% |
| 2017-06-30 | -51.17% |
| 2017-03-31 | -65.33% |
| 2016-12-31 | -43.52% |
| 2016-09-30 | -34.46% |
| 2016-06-30 | -31.51% |
| 2016-03-31 | -90.91% |
| 2015-12-31 | -71.21% |
