Cartesian Therapeutics, Inc. (RNAC) vs Sionna Therapeutics, Inc. (SION)
A side-by-side comparison of Cartesian Therapeutics, Inc. and Sionna Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
RNAC
Cartesian Therapeutics, Inc.
$7.01HealthcareDelayed quote: Oct 6, 2026, 1:39 PM EDT
SION
Sionna Therapeutics, Inc.
$4.55HealthcareDelayed quote: Oct 6, 2026, 1:40 PM EDT
Total return — RNAC vs SION
growth of $100 · dividends reinvested · last 2yRNAC -62.0% (-38.4%/yr)SION -80.6% (-56.0%/yr)RNAC compounded faster over this window
RNAC SION
RNAC vs SION: by the numbers
- •RNAC is the larger company ($206M vs $205M market cap).
- •Both run net losses; SION's is the smaller (0.00% vs -10422.48% net margin).
Metrics side by side
Valuation
| Metric | RNAC | SION |
|---|---|---|
| P/S ratio | 139.47 | N/A |
| P/B ratio | N/A | 0.77 |
Profitability
| Metric | RNAC | SION |
|---|---|---|
| Gross margin | 100.00% | 0.00% |
| Operating margin | -3099.93% | 0.00% |
| Net margin | -10422.48% | 0.00% |
| ROE | N/A | -36.64% |
| ROIC | -33.10% | -40.18% |
Growth (annualized)
| Metric | RNAC | SION |
|---|---|---|
| Revenue CAGR (5Y) | -50.01% | N/A |
| Total return CAGR (5Y) | -44.03% | N/A |
Go deeper
Dig into the metrics
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.