Basis: Trailing twelve months (TTM net income over TTM revenue). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the net profit margin high or low?
The net profit margin of -229.20% is 69% above its 5-year average of -746.33%, near the high end of its 5-year range (-4103.83%–-42.70%).
30.33% above its 12-month average of -328.97%.
Reported quarterly profit margin; no daily interpolation. Q2 FY2026 (2026-06-30): -99.65%.
NET PROFIT MARGIN
-229.20%
NET PROFIT MARGIN AVG TTM
-328.97%
NET PROFIT MARGIN AVG 3Y
-287.42%
NET PROFIT MARGIN AVG 5Y
-746.33%
NET PROFIT MARGIN AVG 10Y
-137.03%
NET PROFIT MARGIN AVG 15Y
N/A
NET PROFIT MARGIN AVG 20Y
N/A
CURRENT VS TTM AVG
+30.33%
CURRENT VS 3Y AVG
+20.26%
CURRENT VS 5Y AVG
+69.29%
CURRENT VS 10Y AVG
-67.26%
CURRENT VS 15Y AVG
N/A
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
-0.35%
median of 862 covered companies
CURRENT VS SECTOR MEDIAN
-65385.71%
vs the sector median at left
ProQR Therapeutics N.V.
Market Cap
$173.76M
Net Profit Margin
-229.20%
TTM Avg
-328.97%
3Y Avg
-287.42%
5Y Avg
-746.33%
Market Cap
$174.27M
Net Profit Margin
-3881.54%
TTM Avg
-6298.52%
3Y Avg
-6043.31%
5Y Avg
-5544.50%
Market Cap
$172.42M
Net Profit Margin
-19.76%
TTM Avg
3.38%
3Y Avg
2.83%
5Y Avg
6.10%
Market Cap
$171.13M
Net Profit Margin
-117.04%
TTM Avg
-61.51%
3Y Avg
-173.42%
5Y Avg
-194.84%
Market Cap
$169.53M
Net Profit Margin
-8.95%
TTM Avg
-22.31%
3Y Avg
-22.43%
5Y Avg
-24.59%
Market Cap
$168.92M
Net Profit Margin
-170.10%
TTM Avg
-145.13%
3Y Avg
-100.04%
5Y Avg
-83.24%
Market Cap
$179.26M
Net Profit Margin
3202.50%
TTM Avg
1601.25%
3Y Avg
554.42%
5Y Avg
279.00%
Market Cap
$168.10M
Net Profit Margin
-435.83%
TTM Avg
-267.41%
3Y Avg
-1429.19%
5Y Avg
-1238.68%
Market Cap
$179.75M
Net Profit Margin
0.00%
TTM Avg
-2904.41%
3Y Avg
-1452.20%
5Y Avg
-968.14%
| NAME | MARKET CAP | NET PROFIT MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| ProQR Therapeutics N.V. (PRQR) | $173.76M | -229.20% | -328.97% | -287.42% | -746.33% |
| Yarrow Bioscience Inc (YARW)vs › | $174.27M | -3881.54% | -6298.52% | -6043.31% | -5544.50% |
| Organogenesis Holdings Inc. (ORGO)vs › | $172.42M | -19.76% | 3.38% | 2.83% | 6.10% |
| Precision BioSciences, Inc. (DTIL)vs › | $171.13M | -117.04% | -61.51% | -173.42% | -194.84% |
| Journey Medical Corporation (DERM)vs › | $169.53M | -8.95% | -22.31% | -22.43% | -24.59% |
| MediWound Ltd. (MDWD)vs › | $168.92M | -170.10% | -145.13% | -100.04% | -83.24% |
| Oramed Pharmaceuticals Inc. (ORMP)vs › | $179.26M | 3202.50% | 1601.25% | 554.42% | 279.00% |
| Cue Biopharma, Inc. (CUE)vs › | $168.10M | -435.83% | -267.41% | -1429.19% | -1238.68% |
| Compass Therapeutics, Inc. (CMPX)vs › | $179.75M | 0.00% | -2904.41% | -1452.20% | -968.14% |
| Canton Strategic Holdings Inc (CNTN)vs › | $180.47M | -6559.27% | 0.00% | 0.00% | 0.00% |
Operating Margin
-275.9%
Net Profit Margin
-229.2%
Net Profit Margin = Net Income / Revenue
Net profit margin is the percentage of revenue that becomes net income after all expenses, taxes, and interest.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | NET PROFIT MARGIN |
|---|---|
| 2026-06-30 | -99.65% |
| 2026-03-31 | -658.29% |
| 2025-12-31 | -190.27% |
| 2025-09-30 | -377.56% |
| 2025-06-30 | -319.07% |
| 2025-03-31 | -223.04% |
| 2024-12-31 | -216.04% |
| 2024-09-30 | -210.98% |
| 2024-06-30 | -42.70% |
| 2024-03-31 | -172.09% |
| 2023-12-31 | -166.96% |
| 2023-09-30 | -416.79% |
| 2023-06-30 | -643.04% |
| 2023-03-31 | -1281.64% |
| 2022-12-31 | -1098.02% |
| 2022-09-30 | -2625.90% |
| 2022-06-30 | -1331.39% |
| 2022-03-31 | -1146.14% |
| 2021-12-31 | -4103.83% |
| 2021-09-30 | -1299.40% |
| 2021-06-30 | -2407.65% |
| 2021-03-31 | 0.00% |
| 2020-12-31 | 0.00% |
| 2020-09-30 | 0.00% |
| 2020-06-30 | 0.00% |
| 2020-03-31 | 0.00% |
| 2019-12-31 | 0.00% |
| 2019-09-30 | 0.00% |
| 2019-06-30 | 0.00% |
| 2019-03-31 | 0.00% |
| 2018-12-31 | -261.97% |
| 2018-09-30 | 0.00% |
| 2018-06-30 | 0.00% |
| 2018-03-31 | 0.00% |
| 2017-12-31 | 737.93% |
| 2017-09-30 | 0.00% |
| 2017-06-30 | 0.00% |
| 2017-03-31 | 0.00% |
| 2016-12-31 | -386.46% |
| 2016-09-30 | 0.00% |
| 2016-06-30 | 0.00% |
| 2016-03-31 | 0.00% |
| 2015-12-31 | -65.12% |
| 2015-09-30 | 0.00% |
| 2015-06-30 | 0.00% |
| 2015-03-31 | 0.00% |
| 2014-12-31 | -659.22% |
| 2014-09-30 | 0.00% |
| 2014-06-30 | 0.00% |
| 2014-03-31 | 0.00% |
| 2013-12-31 | 0.00% |
| 2013-09-30 | 0.00% |
