Organogenesis Holdings Inc. (ORGO) vs ProQR Therapeutics N.V. (PRQR)
A side-by-side comparison of Organogenesis Holdings Inc. and ProQR Therapeutics N.V. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ORGO
Organogenesis Holdings Inc.
$1.33HealthcareDelayed quote: Oct 6, 2026, 1:00 PM EDT
PRQR
ProQR Therapeutics N.V.
$1.65HealthcareDelayed quote: Oct 6, 2026, 1:00 PM EDT
Total return — ORGO vs PRQR
growth of $100 · dividends reinvested · last 10yORGO -86.8% (-18.3%/yr)PRQR -65.9% (-10.2%/yr)PRQR compounded faster over this window
ORGO PRQR
ORGO vs PRQR: by the numbers
- •PRQR is the larger company ($173M vs $170M market cap).
- •Both run net losses; ORGO's is the smaller (-19.76% vs -229.20% net margin).
- •PRQR grew revenue faster over the past five years (94.34% vs 1.05% CAGR).
Metrics side by side
Valuation
| Metric | ORGO | PRQR |
|---|---|---|
| P/S ratio | 0.37 | 8.06 |
| P/B ratio | 1.15 | 1.91 |
| EV / EBITDA | 214.76 | N/A |
| FCF yield | 12.22% | N/A |
Profitability
| Metric | ORGO | PRQR |
|---|---|---|
| Gross margin | 67.59% | 83.01% |
| Operating margin | 9.92% | -275.91% |
| Net margin | -19.76% | -229.20% |
| ROE | -31.32% | -54.27% |
| ROIC | -8.34% | -42.61% |
Growth (annualized)
| Metric | ORGO | PRQR |
|---|---|---|
| Revenue CAGR (5Y) | 1.05% | 94.34% |
| FCF CAGR (5Y) | -5.54% | N/A |
| Total return CAGR (5Y) | -37.41% | -26.23% |
Frequently asked
- Which has grown faster, ORGO or PRQR?
- Over the past five years, PRQR grew revenue faster — ORGO at a 1.05% CAGR versus PRQR at 94.34%.
- How have ORGO and PRQR total returns compared?
- Over the past 5 years, ORGO delivered -37.41% and PRQR delivered -26.23% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Organogenesis ROEProQR Therapeutics ROEOrganogenesis operating marginProQR Therapeutics operating marginOrganogenesis revenue growthProQR Therapeutics revenue growthOrganogenesis free cash flowProQR Therapeutics free cash flow
Organogenesis & ProQR Therapeutics appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.