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Moderna, Inc. (MRNA) Operating Margin: -153.35%

Is Moderna, Inc.’s operating margin high or low?

Moderna, Inc.'s operating margin of -153.35% is 194% below its 5-year average of -52.24%, near the low end of its 5-year range (-158.13%–74.97%).

The operating margin for Moderna, Inc. (MRNA) is -153.35% as of Wednesday, June 10, 2026. It is below its 12-month average by 8.97% (-140.72%).

MRNA Operating Margin Chart

MRNA Operating Margin
-158.13%-28.23% 1Y
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MRNA Average Operating Margin Chart

MRNA Current vs Average Operating Margin Chart

MRNA Operating Margin Metrics

OPERATING MARGIN

-153.35%

OPERATING MARGIN AVG TTM

-140.72%

OPERATING MARGIN AVG 3Y

-73.36%

OPERATING MARGIN AVG 5Y

-52.24%

OPERATING MARGIN AVG 10Y

-190.43%

OPERATING MARGIN AVG 15Y

-190.43%

OPERATING MARGIN AVG 20Y

-190.43%

CURRENT VS TTM AVG

-8.97%

CURRENT VS 3Y AVG

-109.04%

CURRENT VS 5Y AVG

-193.53%

CURRENT VS 10Y AVG

+19.47%

CURRENT VS 15Y AVG

+19.47%

CURRENT VS 20Y AVG

+19.47%

MRNA Competitors' Operating Margin

NAMEMARKET CAPOPERATING MARGINTTM3Y5Y
Moderna, Inc. (MRNA)$18.40B-153.35%-140.72%-73.36%-52.24%
Hologic, Inc. (HOLX)$16.97B17.49%19.66%22.41%27.16%
BioNTech SE (BNTX)$21.81B-51.55%-35.20%5.18%14.03%
Mettler-Toledo International Inc. (MTD)$22.85B28.00%28.45%28.53%27.71%
Waters Corporation (WAT)$23.83B17.08%28.07%28.30%28.33%
Align Technology, Inc. (ALGN)$12.56B14.44%15.23%16.08%17.45%
Baxter International Inc. (BAX)$10.49B-2.65%-1.31%-6.02%0.15%
Veeva Systems Inc. (VEEV)$26.73B28.79%26.93%23.33%24.40%
Charles River Laboratories International, Inc. (CRL)$9.06B11.77%9.13%12.39%13.51%
Bio-Rad Laboratories, Inc. (BIO)$7.89B9.25%10.48%12.70%14.08%

Operating Efficiency

Gross Margin

-13.9%

Operating Margin

-153.3%

Moderna, Inc. Operating Margin Formula & Definition

Operating Margin = Operating Income / Revenue

Operating margin is the percentage of revenue remaining after operating expenses, reflecting operating efficiency.

Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute

Moderna, Inc. Operating Margin FAQ

What is the operating margin for Moderna, Inc. (MRNA)?
The operating margin for MRNA stock is -153.35%.
Is Moderna, Inc.'s operating margin high or low?
Moderna, Inc.'s operating margin of -153.35% is 194% below its 5-year average of -52.24%, near the low end of its 5-year range (-158.13%–74.97%).
What is the TTM average operating margin for Moderna, Inc. (MRNA)?
The TTM average operating margin for MRNA stock is -140.72%.
What is the 3Y average operating margin for Moderna, Inc. (MRNA)?
The 3Y average operating margin for MRNA stock is -73.36%.
What is the 5Y average operating margin for Moderna, Inc. (MRNA)?
The 5Y average operating margin for MRNA stock is -52.24%.
What is the 10Y average operating margin for Moderna, Inc. (MRNA)?
The 10Y average operating margin for MRNA stock is -190.43%.
What is the 15Y average operating margin for Moderna, Inc. (MRNA)?
The 15Y average operating margin for MRNA stock is -190.43%.
What is the 20Y average operating margin for Moderna, Inc. (MRNA)?
The 20Y average operating margin for MRNA stock is -190.43%.

Moderna, Inc. Operating Margin History

DATEOPERATING MARGIN
2025-12-31-158.13%
2024-12-31-123.32%
2023-12-31-61.90%
2022-12-3149.91%
2021-12-3174.97%
2020-12-31-94.99%
2019-12-31-906.38%
2018-12-31-347.13%
2017-12-31-130.87%
2016-12-31-206.44%

About Moderna, Inc.

Moderna, Inc., a biotechnology firm, is dedicated to the discovery, development, and commercialization of messenger RNA (mRNA) based therapies and preventive medicines. Its extensive research and development efforts target a broad spectrum of medical needs, including infectious diseases, cancer immunology, rare conditions, cardiovascular ailments, and autoimmune disorders, with operations spanning the United States, Europe, and other global markets. The company's diverse product pipeline encompasses various vaccine candidates: those for respiratory illnesses like COVID-19, influenza, and respiratory syncytial virus (RSV); latent viral infections such as cytomegalovirus (CMV), Epstein-Barr virus (EBV), human immunodeficiency virus (HIV), herpes simplex virus (HSV), and varicella-zoster virus (VZV); and public health threats like Zika and Nipah. Additionally, Moderna is advancing systemic secreted and cell surface-targeted therapeutics, an array of cancer vaccines (including personalized, KRAS, and checkpoint varieties), intratumoral immuno-oncology products, localized regenerative treatments, systemic intracellular medicines, and inhaled pulmonary solutions. Moderna maintains strategic alliances with several prominent entities, including AstraZeneca PLC, Merck & Co., Inc., Vertex Pharmaceuticals Incorporated, Vertex Pharmaceuticals (Europe) Limited, Carisma Therapeutics, Inc., Metagenomi, Inc., the Defense Advanced Research Projects Agency (DARPA), the Biomedical Advanced Research and Development Authority (BARDA), the Institute for Life Changing Medicines, and The Bill & Melinda Gates Foundation. It also holds a collaboration and license agreement with Chiesi Farmaceutici S.P.A. Founded in 2010 as Moderna Therapeutics, Inc., the company officially became Moderna, Inc. in August 2018. Its corporate headquarters are located in Cambridge, Massachusetts.

Cambridge, MA
5,800 employees
Healthcare / Biotechnology
Sector
Healthcare
Industry
Biotechnology
CEO
Stéphane Bancel