Basis: Trailing twelve months (TTM). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the operating margin high or low?
The operating margin of -48.72% is 80% above its 5-year average of -242.10%, near the high end of its 5-year range (-624.36%–48.95%).
34.55% above its 12-month average of -74.44%.
Reported quarterly operating margin; no daily interpolation. Q2 FY2026 (2026-06-30): -42.19%.
OPERATING MARGIN
-48.72%
OPERATING MARGIN AVG TTM
-74.44%
OPERATING MARGIN AVG 3Y
-247.52%
OPERATING MARGIN AVG 5Y
-242.10%
OPERATING MARGIN AVG 10Y
-237.88%
OPERATING MARGIN AVG 15Y
-200.54%
OPERATING MARGIN AVG 20Y
N/A
CURRENT VS TTM AVG
+34.55%
CURRENT VS 3Y AVG
+80.32%
CURRENT VS 5Y AVG
+79.88%
CURRENT VS 10Y AVG
+79.52%
CURRENT VS 15Y AVG
+75.71%
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
0.00%
median of 605 covered companies
CURRENT VS SECTOR MEDIAN
N/A
vs the sector median at left
MacroGenics, Inc.
Market Cap
$229.14M
Operating Margin
-48.72%
TTM Avg
-74.44%
3Y Avg
-247.52%
5Y Avg
-242.10%
Market Cap
$232.19M
Operating Margin
-1026.28%
TTM Avg
-515.73%
3Y Avg
-257.87%
5Y Avg
-257.87%
Market Cap
$225.46M
Operating Margin
-31.37%
TTM Avg
-39.87%
3Y Avg
-74.09%
5Y Avg
-70.30%
Market Cap
$221.42M
Operating Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
Market Cap
$223.45M
Operating Margin
28.94%
TTM Avg
-2955.01%
3Y Avg
-29613.43%
5Y Avg
-19789.03%
Market Cap
$236.20M
Operating Margin
9.95%
TTM Avg
-10.78%
3Y Avg
-18.24%
5Y Avg
-54.36%
Market Cap
$236.58M
Operating Margin
-1488.31%
TTM Avg
-4815.32%
3Y Avg
-6115.40%
5Y Avg
-4078.06%
Market Cap
$237.27M
Operating Margin
0.56%
TTM Avg
-0.74%
3Y Avg
-7.55%
5Y Avg
-6.74%
Market Cap
$237.74M
Operating Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
| NAME | MARKET CAP | OPERATING MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| MacroGenics, Inc. (MGNX) | $229.14M | -48.72% | -74.44% | -247.52% | -242.10% |
| BioAge Labs Inc. (BIOA)vs › | $232.19M | -1026.28% | -515.73% | -257.87% | -257.87% |
| Biodesix, Inc. (BDSX)vs › | $225.46M | -31.37% | -39.87% | -74.09% | -70.30% |
| Nautilus Biotechnolgy, Inc. (NAUT)vs › | $221.42M | 0.00% | 0.00% | 0.00% | 0.00% |
| Keros Therapeutics, Inc. (KROS)vs › | $223.45M | 28.94% | -2955.01% | -29613.43% | -19789.03% |
| Akebia Therapeutics, Inc. (AKBA)vs › | $236.20M | 9.95% | -10.78% | -18.24% | -54.36% |
| CAMP4 Therapeutics Corporation (CAMP)vs › | $236.58M | -1488.31% | -4815.32% | -6115.40% | -4078.06% |
| High Tide Inc. (HITI)vs › | $237.27M | 0.56% | -0.74% | -7.55% | -6.74% |
| Galectin Therapeutics Inc. (GALT)vs › | $237.74M | 0.00% | 0.00% | 0.00% | 0.00% |
| InflaRx N.V. (IFRX)vs › | $238.61M | -164525.50% | -98218.45% | -66780.63% | -44520.42% |
Gross Margin
71.1%
Operating Margin
-48.7%
Operating Margin = Operating Income / Revenue
Operating margin is the percentage of revenue remaining after operating expenses, reflecting operating efficiency.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | OPERATING MARGIN |
|---|---|
| 2026-06-30 | -42.19% |
| 2026-03-31 | -160.96% |
| 2025-12-31 | -29.34% |
| 2025-09-30 | 25.59% |
| 2025-06-30 | -165.27% |
| 2025-03-31 | -323.10% |
| 2024-12-31 | -298.01% |
| 2024-09-30 | 48.95% |
| 2024-06-30 | -538.86% |
| 2024-03-31 | -590.40% |
| 2023-12-31 | -460.39% |
| 2023-09-30 | -341.46% |
| 2023-06-30 | -342.28% |
| 2023-03-31 | -156.87% |
| 2022-12-31 | 16.39% |
| 2022-09-30 | -59.80% |
| 2022-06-30 | -160.76% |
| 2022-03-31 | -624.36% |
| 2021-12-31 | -411.65% |
| 2021-09-30 | -338.32% |
| 2021-06-30 | -130.96% |
| 2021-03-31 | -303.85% |
| 2020-12-31 | -4.12% |
| 2020-09-30 | -207.49% |
| 2020-06-30 | -302.57% |
| 2020-03-31 | -350.47% |
| 2019-12-31 | -153.44% |
| 2019-09-30 | -210.99% |
| 2019-06-30 | -530.38% |
| 2019-03-31 | -501.39% |
| 2018-12-31 | -253.35% |
| 2018-09-30 | -169.78% |
| 2018-06-30 | -238.86% |
| 2018-03-31 | -1115.53% |
| 2017-12-31 | 68.03% |
| 2017-09-30 | -4435.32% |
| 2017-06-30 | -3809.34% |
| 2017-03-31 | -2989.67% |
| 2016-12-31 | -371.87% |
| 2016-09-30 | -1701.34% |
| 2016-06-30 | 51.08% |
| 2016-03-31 | -1618.23% |
| 2015-12-31 | -303.73% |
| 2015-09-30 | -105.19% |
| 2015-06-30 | -380.31% |
| 2015-03-31 | 63.42% |
| 2014-12-31 | -353.64% |
| 2014-09-30 | -21.48% |
| 2014-06-30 | -133.23% |
| 2014-03-31 | -21587482.09% |
| 2013-12-31 | -21.75% |
| 2013-09-30 | 35.59% |
| 2013-06-30 | -2.15% |
| 2013-03-31 | -33.10% |
| 2012-12-31 | -24.10% |
| 2012-09-30 | 16.73% |
