Akebia Therapeutics, Inc. (AKBA) vs MacroGenics, Inc. (MGNX)

A side-by-side comparison of Akebia Therapeutics, Inc. and MacroGenics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

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Total return — AKBA vs MGNX

growth of $100 · dividends reinvested · last 10y
AKBA -89.8% (-20.4%/yr)MGNX -87.5% (-18.7%/yr)MGNX compounded faster over this window
050100150200Start $10020182020202220242026$10$13
AKBA MGNX

AKBA vs MGNX: by the numbers

  • •AKBA is the larger company ($240M vs $236M market cap).
  • •Both run net losses; MGNX's is the smaller (-8.70% vs -13.54% net margin).
  • •MGNX grew revenue faster over the past five years (7.33% vs -0.26% CAGR).

Metrics side by side

Valuation

MetricAKBAMGNX
P/S ratio1.101.41
P/B ratio9.615.51
FCF yield16.72%N/A

Profitability

MetricAKBAMGNX
Gross margin79.48%71.12%
Operating margin9.95%-48.72%
Net margin-13.54%-8.70%
ROE-118.58%-34.04%
ROIC-7.08%-16.87%

Growth (annualized)

MetricAKBAMGNX
Revenue CAGR (5Y)-0.26%7.33%
Total return CAGR (5Y)-20.07%-28.42%

Frequently asked

Which has grown faster, AKBA or MGNX?
Over the past five years, MGNX grew revenue faster — AKBA at a -0.26% CAGR versus MGNX at 7.33%.
How have AKBA and MGNX total returns compared?
Over the past 10 years, AKBA delivered -20.53% and MGNX delivered -18.75% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.