Lyell Immunopharma (LYEL) Metrics: History & Chart

Lyell Immunopharma, Inc.(LYEL)

Biotechnology · South San Francisco, CA

$8.70-0.37 (-4.03%)

Delayed quote: Oct 6, 2026, 3:15 PM EDT

About Lyell Immunopharma, Inc.

Lyell Immunopharma, Inc., a clinical-stage cell therapy company, develops chimeric antigen receptor (CAR) T-cell product candidates for patients with hematologic malignancies and solid tumors. The company’s lead product candidate include rondecabtagene autoleucel, an autologous dual-targeting CD19/CD20 CAR T-cell therapy in development, which is in pivotal PiNACLE trial in the 3L+ setting and in a Phase 1/2 clinical trial in the 2L setting, as well as a second pivotal trial, PiNACLE-H2H, which is a Phase 3 head-to-head CAR T cell therapy randomized controlled trial of ronde-cel for LBCL in the 2L setting for the treatment of large B-cell lymphoma; and LYL273, a GCC-targeted CAR T-cell product candidate enhanced with CD19 CAR expression and controlled cytokine release designed to improve CAR T-cell expansion, immune cell infiltration, and cancer cell killing in the hostile solid tumor microenvironment, which is in Phase 1 clinical trial for the treatment of refractory metastatic colorectal cancer. The company develops therapies using various approaches, such as c-Jun overexpression and NR4A3 gene knockout, to endow functional resistance to exhaustion; Epi-R to generate population of stem-like T cells with reduced exhaustion and improved proliferation and antitumor activity; and CD62L positive enrichment to generate CAR T cells with enhanced antitumor activity. Lyell Immunopharma, Inc. was incorporated in 2018 and is headquartered in South San Francisco, California.

South San Francisco, CA

161 employees

www.lyell.com

Healthcare / Biotechnology

Sector: Healthcare
Industry: Biotechnology
CEO: Lynn Seely

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Third-Party DCF Estimate (FMP)	N/A
Price Gap vs Third-Party Estimate	N/A

7D Total Return	-6.88%
30D Total Return	-36.88%
YTD Total Return	-70.53%
1Y Total Return	-48.90%
3Y Total Return	-69.57%
5Y Total Return	-96.26%
10Y Total Return	N/A
15Y Total Return	N/A
20Y Total Return	N/A

2026	-70.53%
2025	+140.47%
2024	-67.01%
2023	-44.09%
2022	-55.17%
2021	N/A
2020

CAGR TTM	-48.74%
CAGR 3Y	-32.73%
CAGR 5Y	-48.18%
CAGR 10Y	N/A
CAGR 15Y	N/A
CAGR 20Y	N/A

PE Ratio	N/A
PE Ratio Avg TTM	N/A
PE Ratio Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

All Metrics

LYEL Valuation Metrics

LYEL Stock Price Metrics

LYEL Dividend Metrics

LYEL Growth Rate Metrics

LYEL Discounted Cash Flow Metrics

LYEL Returns By Period

LYEL Yearly Returns

LYEL Average Annual Returns By Period (CAGR)

LYEL Revenue Metrics

LYEL PE Ratio Metrics

LYEL PS Ratio Metrics

LYEL PB Ratio Metrics

LYEL Price to Free Cash Flow Ratio Metrics

LYEL Debt to Equity Ratio Metrics

LYEL PEG Ratio Metrics

LYEL FCF Yield

LYEL Earnings Yield

LYEL EBITDA Yield

LYEL OCF Yield

LYEL EV/EBIT Ratio Metrics

LYEL EV/EBITDA Ratio Metrics

LYEL EV/Assets Ratio Metrics

LYEL EV/Sales Ratio Metrics

LYEL Current Ratio Metrics

LYEL Quick Ratio Metrics

LYEL ROIC Metrics

LYEL Return on Assets Metrics

LYEL Return on Equity Metrics

LYEL Net Profit Margin Metrics

LYEL Gross Profit Margin Metrics

LYEL Tax Rate Metrics

PS Ratio	7848.57
PS Ratio Avg TTM	10656.04
PS Ratio Avg 3Y	5826.11
Current VS TTM Avg	-26.35%
Current VS 3Y Avg	+34.71%
Current VS 5Y Avg	+129.45%

PB Ratio	0.91
PB Ratio Avg TTM	1.27
PB Ratio Avg 3Y	0.82
Current VS TTM Avg	-28.21%
Current VS 3Y Avg	+11.26%
Current VS 5Y Avg	-9.26%

PFCF Ratio	N/A
PFCF Ratio Avg TTM	N/A
PFCF Ratio Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

Debt/Equity Ratio	0.16
Debt/Equity Ratio Avg TTM	0.18
Debt/Equity Ratio Avg 3Y	0.14
Current VS TTM Avg	-11.01%
Current VS 3Y Avg	+13.51%
Current VS 5Y Avg	+37.84%

PEG Ratio	N/A
PEG Ratio Avg TTM	N/A
PEG Ratio Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

FCF Yield	N/A
FCF Yield Avg TTM	N/A
FCF Yield Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

Earnings Yield	N/A
Earnings Yield Avg TTM	N/A
Earnings Yield Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

EBITDA Yield	N/A
EBITDA Yield Avg TTM	N/A
EBITDA Yield Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

OCF Yield	N/A
OCF Yield Avg TTM	N/A
OCF Yield Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

Ev/Ebit Ratio	N/A
Ev/Ebit Ratio Avg TTM	N/A
Ev/Ebit Ratio Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

Ev/Ebitda Ratio	N/A
Ev/Ebitda Ratio Avg TTM	N/A
Ev/Ebitda Ratio Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

Ev/Assets Ratio	0.57
Ev/Assets Ratio Avg TTM	0.86
Ev/Assets Ratio Avg 3Y	0.55
Current VS TTM Avg	-33.87%
Current VS 3Y Avg	+4.13%
Current VS 5Y Avg	-18.11%

Ev/Sales Ratio	6513.35
Ev/Sales Ratio Avg TTM	9334.19
Ev/Sales Ratio Avg 3Y	4911.03
Current VS TTM Avg	-30.22%
Current VS 3Y Avg	+32.63%
Current VS 5Y Avg	+137.00%

Current Ratio	5.36
Current Ratio Avg TTM	7.16
Current Ratio Avg 3Y	11.30
Current VS TTM Avg	-25.22%
Current VS 3Y Avg	-52.61%
Current VS 5Y Avg	-57.28%

Quick Ratio	5.36
Quick Ratio Avg TTM	7.16
Quick Ratio Avg 3Y	11.30
Current VS TTM Avg	-25.22%
Current VS 3Y Avg	-52.61%
Current VS 5Y Avg	-57.28%

ROIC	(70.80%)
ROIC Avg 3Y	(59.00%)
ROIC Avg 5Y	(44.27%)
Current VS 3Y Avg	-19.99%
Current VS 5Y Avg	-59.92%
Current VS 10Y Avg	-65.85%

ROA	(79.86%)
ROA Avg TTM	(16.65%)
ROA Avg 3Y	(8.91%)
Current VS TTM Avg	-379.64%
Current VS 3Y Avg	-795.88%
Current VS 5Y Avg	-986.36%

ROE	(106.27%)
ROE Avg TTM	(103.34%)
ROE Avg 3Y	(70.05%)
Current VS TTM Avg	-2.84%
Current VS 3Y Avg	-51.71%
Current VS 5Y Avg	-100.86%

Net Profit Margin	(920285.19%)
Net Profit Margin Avg TTM	(1092886.33%)
Net Profit Margin Avg 3Y	(869836.18%)
Current VS TTM Avg	+15.79%
Current VS 3Y Avg	-5.80%
Current VS 5Y Avg	-40.33%

Gross Profit Margin	(31952.78%)
Gross Pft Margin Avg TTM	(23220.00%)
Gross Pft Margin Avg 3Y	(6243.93%)
Current VS TTM Avg	-37.61%
Current VS 3Y Avg	-411.74%
Current VS 5Y Avg	-2189.58%

Tax Rate	0.00%
Tax Rate Avg 3Y	0.00%
Tax Rate Avg 5Y	0.00%
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A
Current VS 10Y Avg	N/A