Basis: Trailing twelve months (TTM). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the operating margin high or low?
The operating margin of -290.68% is 45% above its 5-year average of -531.04%, near the high end of its 5-year range (-1410.21%–-75.98%).
19.57% above its 12-month average of -361.41%.
Reported quarterly operating margin; no daily interpolation. Q2 FY2026 (2026-06-30): -397.88%.
OPERATING MARGIN
-290.68%
OPERATING MARGIN AVG TTM
-361.41%
OPERATING MARGIN AVG 3Y
-551.54%
OPERATING MARGIN AVG 5Y
-531.04%
OPERATING MARGIN AVG 10Y
N/A
OPERATING MARGIN AVG 15Y
N/A
OPERATING MARGIN AVG 20Y
N/A
CURRENT VS TTM AVG
+19.57%
CURRENT VS 3Y AVG
+47.30%
CURRENT VS 5Y AVG
+45.26%
CURRENT VS 10Y AVG
N/A
CURRENT VS 15Y AVG
N/A
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
0.00%
median of 863 covered companies
CURRENT VS SECTOR MEDIAN
N/A
vs the sector median at left
C4 Therapeutics, Inc.
Market Cap
$313.46M
Operating Margin
-290.68%
TTM Avg
-361.41%
3Y Avg
-551.54%
5Y Avg
-531.04%
Market Cap
$320.02M
Operating Margin
-18.00%
TTM Avg
-67.22%
3Y Avg
-104.89%
5Y Avg
-90.63%
Market Cap
$319.83M
Operating Margin
-59.40%
TTM Avg
-73.74%
3Y Avg
-78.11%
5Y Avg
-79.89%
Market Cap
$321.67M
Operating Margin
9.36%
TTM Avg
0.56%
3Y Avg
-8.17%
5Y Avg
-15.92%
Market Cap
$322.03M
Operating Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
Market Cap
$322.69M
Operating Margin
-65.36%
TTM Avg
-64.13%
3Y Avg
-75.36%
5Y Avg
-72.00%
Market Cap
$304.06M
Operating Margin
-144.71%
TTM Avg
-144.71%
3Y Avg
-144.71%
5Y Avg
-144.71%
Market Cap
$304.71M
Operating Margin
0.00%
TTM Avg
0.00%
3Y Avg
-6360.33%
5Y Avg
-12157.15%
Market Cap
$325.51M
Operating Margin
-188.25%
TTM Avg
-178.83%
3Y Avg
-158.00%
5Y Avg
-158.00%
| NAME | MARKET CAP | OPERATING MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| C4 Therapeutics, Inc. (CCCC) | $313.46M | -290.68% | -361.41% | -551.54% | -531.04% |
| Agenus Inc. (AGEN)vs › | $320.02M | -18.00% | -67.22% | -104.89% | -90.63% |
| Avita Medical Inc. (RCEL)vs › | $319.83M | -59.40% | -73.74% | -78.11% | -79.89% |
| Sanara MedTech Inc. (SMTI)vs › | $321.67M | 9.36% | 0.56% | -8.17% | -15.92% |
| Cabaletta Bio, Inc. (CABA)vs › | $322.03M | 0.00% | 0.00% | 0.00% | 0.00% |
| ClearPoint Neuro, Inc. (CLPT)vs › | $322.69M | -65.36% | -64.13% | -75.36% | -72.00% |
| Mobia Medical, Inc. Common Stock (MOBI)vs › | $304.06M | -144.71% | -144.71% | -144.71% | -144.71% |
| Benitec Biopharma Inc. (BNTC)vs › | $304.71M | 0.00% | 0.00% | -6360.33% | -12157.15% |
| CapsoVision, Inc. (CV)vs › | $325.51M | -188.25% | -178.83% | -158.00% | -158.00% |
| Larimar Therapeutics, Inc. (LRMR)vs › | $292.95M | 0.00% | 0.00% | 0.00% | 0.00% |
Gross Margin
77.8%
Operating Margin
-290.7%
Operating Margin = Operating Income / Revenue
Operating margin is the percentage of revenue remaining after operating expenses, reflecting operating efficiency.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | OPERATING MARGIN |
|---|---|
| 2026-06-30 | -397.88% |
| 2026-03-31 | -451.64% |
| 2025-12-31 | -210.10% |
| 2025-09-30 | -306.43% |
| 2025-06-30 | -440.99% |
| 2025-03-31 | -402.93% |
| 2024-12-31 | -728.39% |
| 2024-09-30 | -183.86% |
| 2024-06-30 | -178.59% |
| 2024-03-31 | -1060.18% |
| 2023-12-31 | -1147.72% |
| 2023-09-30 | -251.16% |
| 2023-06-30 | -1410.21% |
| 2023-03-31 | -963.77% |
| 2022-12-31 | -1341.73% |
| 2022-09-30 | -481.02% |
| 2022-06-30 | -197.95% |
| 2022-03-31 | -409.84% |
| 2021-12-31 | -75.98% |
| 2021-09-30 | -285.34% |
| 2021-06-30 | -226.11% |
| 2021-03-31 | -552.59% |
| 2020-12-31 | -228.79% |
| 2020-09-30 | -217.23% |
| 2020-06-30 | -112.30% |
| 2020-03-31 | -181.02% |
| 2019-12-31 | -127.90% |
| 2019-09-30 | -186.45% |
| 2019-06-30 | -191.53% |
| 2019-03-31 | -191.53% |
