Basis: Current FMP quote-based enterprise value / four-quarter operating income plus matched D&A. Source: stored company filings and market data; unavailable inputs remain N/A.
Is the EV/EBITDA ratio high or low?
The EV/EBITDA ratio of 473.84x is 898% above its estimated 5-year average of 47.50x, near the high end of its estimated 5-year range (4.38x–551.60x).
As of 2026-10-06T14:50:54.110Z. 139.98% above its estimated 12-month average of 197.45x.
Calculation as of: 2026-10-06T14:50:54.110Z.
Quote observation: 2026-10-06T14:50:11.000Z. Amounts in USD. The price header may show a later quote.
FMP input reference: 725adddd40c1a2280488f538213825861a91d0760fd62c66cabbd6cf27e99fae
Historical values estimate market capitalization from statement-period weighted shares. Comparisons with the current quote-based value are approximate. Only filing versions delivered by FMP are available for the historical calculation. Historical series through 2026-10-05.
Historical values estimate market capitalization from statement-period weighted shares. Comparisons with the current quote-based value are approximate. Only filing versions delivered by FMP are available for the historical calculation.
EV/EBITDA RATIO
473.84x
EV/EBITDA RATIO AVG TTM
197.45x
EV/EBITDA RATIO AVG 3Y
59.80x
EV/EBITDA RATIO AVG 5Y
47.50x
EV/EBITDA RATIO AVG 10Y
13.27x
EV/EBITDA RATIO AVG 15Y
11.30x
EV/EBITDA RATIO AVG 20Y
10.93x
CURRENT VS TTM AVG
+139.98%
CURRENT VS 3Y AVG
+692.31%
CURRENT VS 5Y AVG
+897.64%
CURRENT VS 10Y AVG
+3471.18%
CURRENT VS 15Y AVG
+4093.21%
CURRENT VS 20Y AVG
+4235.16%
SECTOR MEDIAN · HEALTHCARE
15.46x
median of 182 covered companies
CURRENT VS SECTOR MEDIAN
+2964.94%
vs the sector median at left
Anika Therapeutics, Inc.
Market Cap
$256.28M
EV/EBITDA Ratio
473.84x
TTM Avg
197.45x
3Y Avg
59.80x
5Y Avg
47.50x
Market Cap
$254.52M
EV/EBITDA Ratio
N/A
TTM Avg
N/A
3Y Avg
N/A
5Y Avg
N/A
Market Cap
$258.47M
EV/EBITDA Ratio
N/A
TTM Avg
N/A
3Y Avg
N/A
5Y Avg
N/A
Market Cap
$260.47M
EV/EBITDA Ratio
N/A
TTM Avg
N/A
3Y Avg
N/A
5Y Avg
N/A
Market Cap
$262.42M
EV/EBITDA Ratio
N/A
TTM Avg
10.21x
3Y Avg
10.21x
5Y Avg
10.68x
Market Cap
$250.48M
EV/EBITDA Ratio
N/A
TTM Avg
N/A
3Y Avg
N/A
5Y Avg
N/A
Market Cap
$243.07M
EV/EBITDA Ratio
N/A
TTM Avg
N/A
3Y Avg
N/A
5Y Avg
N/A
Market Cap
$243.81M
EV/EBITDA Ratio
N/A
TTM Avg
28.93x
3Y Avg
31.09x
5Y Avg
27.66x
| NAME | MARKET CAP | EV/EBITDA RATIO | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Anika Therapeutics, Inc. (ANIK) | $256.28M | 473.84x | 197.45x | 59.80x | 47.50x |
| Century Therapeutics, Inc. (IPSC)vs › | $254.52M | N/A | N/A | N/A | N/A |
| Inhibikase Therapeutics, Inc. (IKT)vs › | $258.47M | N/A | N/A | N/A | N/A |
| AC Immune S.A. (ACIU)vs › | $259.01M | N/A | 15.20x | 12.43x | 15.17x |
| Eupraxia Pharmaceuticals Inc. (EPRX)vs › | $260.47M | N/A | N/A | N/A | N/A |
| EyePoint Pharmaceuticals, Inc. (EYPT)vs › | $262.42M | N/A | 10.21x | 10.21x | 10.68x |
| Lexeo Therapeutics, Inc. Common Stock (LXEO)vs › | $250.48M | N/A | N/A | N/A | N/A |
| Greenwich LifeSciences, Inc. (GLSI)vs › | $243.07M | N/A | N/A | N/A | N/A |
| Lifecore Biomedical, Inc. (LFCR)vs › | $243.81M | N/A | 28.93x | 31.09x | 27.66x |
| Invivyd, Inc. (IVVD)vs › | $243.08M | N/A | N/A | N/A | N/A |
At 473.8, EV/EBITDA is above its estimated 20-year median — higher than 99% of readings in its estimated 20-year history.
Historical values estimate market capitalization from statement-period weighted shares. Comparisons with the current quote-based value are approximate. Only filing versions delivered by FMP are available for the historical calculation.
estimated 20-year low
0.6
median
11.0
estimated 20-year high
551.6
EV/EBITDA = Enterprise Value / EBITDA (TTM)
Enterprise value to EBITDA is a capital-structure-neutral valuation multiple, useful for comparing companies with different debt levels and tax rates.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | EV/EBITDA RATIO |
|---|---|
| 2026-10-05 | 490.92x |
| 2026-10-02 | 474.29x |
| 2026-10-01 | 481.15x |
| 2026-09-30 | 489.07x |
| 2026-09-29 | 496.72x |
| 2026-09-28 | 515.98x |
| 2026-09-25 | 507.80x |
| 2026-09-24 | 504.11x |
| 2026-09-23 | 508.07x |
| 2026-09-22 | 521.52x |
| 2026-09-21 | 516.51x |
| 2026-09-18 | 519.41x |
| 2026-09-17 | 525.22x |
| 2026-09-16 | 520.20x |
| 2026-09-15 | 522.05x |
| 2026-09-14 | 529.44x |
| 2026-09-11 | 520.73x |
| 2026-09-10 | 524.16x |
| 2026-09-09 | 521.26x |
| 2026-09-08 | 525.48x |
| 2026-09-04 | 519.41x |
| 2026-09-03 | 524.43x |
| 2026-09-02 | 538.94x |
| 2026-09-01 | 527.33x |
| 2026-08-31 | 521.00x |
| 2026-08-28 | 527.06x |
| 2026-08-27 | 520.20x |
| 2026-08-26 | 542.37x |
| 2026-08-25 | 534.98x |
| 2026-08-24 | 533.40x |
| 2026-08-21 | 545.01x |
| 2026-08-20 | 533.40x |
| 2026-08-19 | 531.29x |
| 2026-08-18 | 539.47x |
| 2026-08-17 | 536.83x |
| 2026-08-14 | 537.62x |
| 2026-08-13 | 528.91x |
| 2026-08-12 | 551.60x |
| 2026-08-11 | 530.49x |
| 2026-08-10 | 515.98x |
| 2026-08-07 | 535.51x |
| 2026-08-06 | 502.26x |
| 2026-08-05 | 476.67x |
| 2026-08-04 | 487.75x |
| 2026-08-03 | 517.57x |
| 2026-07-31 | 479.04x |
| 2026-07-30 | 447.12x |
| 2026-03-02 | 7.71x |
| 2026-02-27 | 7.74x |
| 2026-02-26 | 6.73x |
| 2026-02-25 | 5.54x |
| 2026-02-24 | 5.48x |
| 2026-02-23 | 5.53x |
| 2026-02-20 | 5.34x |
| 2026-02-19 | 5.39x |
| 2026-02-18 | 5.27x |
| 2026-02-17 | 5.21x |
| 2026-02-13 | 5.07x |
| 2026-02-12 | 4.98x |
| 2026-02-11 | 5.10x |
| 2026-02-10 | 5.15x |
| 2026-02-09 | 5.08x |
| 2026-02-06 | 5.23x |
| 2026-02-05 | 5.13x |
| 2026-02-04 | 5.37x |
| 2026-02-03 | 4.95x |
| 2026-02-02 | 4.70x |
| 2026-01-30 | 4.44x |
| 2026-01-29 | 4.39x |
| 2026-01-28 | 4.38x |
| 2026-01-27 | 4.39x |
| 2026-01-26 | 4.44x |
| 2026-01-23 | 4.49x |
| 2026-01-22 | 4.54x |
| 2026-01-21 | 4.63x |
| 2026-01-20 | 4.59x |
| 2026-01-16 | 4.49x |
| 2026-01-15 | 4.63x |
| 2026-01-14 | 4.64x |
| 2026-01-13 | 4.65x |
| 2026-01-12 | 4.56x |
| 2026-01-09 | 4.63x |
| 2026-01-08 | 4.65x |
| 2026-01-07 | 4.83x |
| 2026-01-06 | 4.72x |
| 2026-01-05 | 4.60x |
| 2026-01-02 | 4.52x |
| 2025-12-31 | 4.69x |
| 2025-12-30 | 4.65x |
| 2025-12-29 | 4.63x |
| 2025-12-26 | 4.65x |
| 2025-12-24 | 4.60x |
| 2025-12-23 | 4.54x |
| 2025-12-22 | 4.56x |
| 2025-12-19 | 4.66x |
| 2025-12-18 | 4.65x |
| 2025-12-17 | 4.57x |
| 2025-12-16 | 4.62x |
| 2025-12-15 | 4.66x |
| 2025-12-12 | 4.65x |
| 2025-12-11 | 4.61x |
| 2025-12-10 | 4.71x |
| 2025-12-09 | 4.63x |
| 2025-12-08 | 4.70x |
| 2025-12-05 | 4.68x |
| 2025-12-04 | 4.61x |
| 2025-12-03 | 4.60x |
| 2025-12-02 | 4.57x |
| 2025-12-01 | 4.78x |
| 2025-11-28 | 4.86x |
| 2025-11-26 | 4.80x |
| 2025-11-25 | 4.92x |
| 2025-11-24 | 4.85x |
| 2025-11-21 | 4.86x |
| 2025-11-20 | 4.49x |
| 2025-11-19 | 4.63x |
| 2025-11-18 | 4.72x |
| 2025-11-17 | 4.71x |
| 2025-11-14 | 4.93x |
| 2025-11-13 | 5.00x |
| 2025-11-12 | 5.00x |
| 2025-11-11 | 5.02x |
| 2025-11-10 | 4.98x |
| 2025-11-07 | 4.84x |
| 2025-11-06 | 4.78x |
| 2025-07-30 | 64.75x |
| 2025-07-29 | 96.99x |
| 2025-07-28 | 98.78x |
| 2025-07-25 | 100.58x |
| 2025-07-24 | 98.57x |
| 2025-07-23 | 100.58x |
| 2025-07-22 | 95.31x |
| 2025-07-21 | 92.04x |
| 2025-07-18 | 90.04x |
| 2025-07-17 | 97.84x |
| 2025-07-16 | 97.31x |
| 2025-07-15 | 95.31x |
| 2025-07-14 | 100.89x |
| 2025-07-11 | 98.15x |
| 2025-07-10 | 103.53x |
| 2025-07-09 | 96.78x |
| 2025-07-08 | 95.10x |
| 2025-07-07 | 93.31x |
| 2025-07-03 | 97.94x |
| 2025-07-02 | 97.94x |
| 2025-07-01 | 90.36x |
| 2025-06-30 | 90.88x |
| 2025-06-27 | 92.57x |
| 2025-06-26 | 93.52x |
| 2025-06-25 | 96.57x |
| 2025-06-24 | 97.73x |
| 2025-06-23 | 94.47x |
| 2025-06-20 | 90.99x |
| 2025-06-18 | 96.36x |
| 2025-06-17 | 95.62x |
| 2025-06-16 | 96.47x |
| 2025-06-13 | 94.57x |
| 2025-06-12 | 98.15x |
| 2025-06-11 | 98.57x |
| 2025-06-10 | 101.10x |
| 2025-06-09 | 100.79x |
| 2025-06-06 | 99.00x |
| 2025-06-05 | 97.31x |
| 2025-06-04 | 102.16x |
| 2025-06-03 | 101.52x |
| 2025-06-02 | 100.05x |
| 2025-05-30 | 96.89x |
| 2025-05-29 | 98.05x |
| 2025-05-28 | 96.57x |
| 2025-05-27 | 96.78x |
| 2025-05-23 | 97.84x |
| 2025-05-22 | 103.42x |
| 2025-05-21 | 102.79x |
| 2025-05-20 | 105.42x |
| 2025-05-19 | 107.53x |
| 2025-05-16 | 107.85x |
| 2025-05-15 | 108.37x |
| 2025-05-14 | 98.68x |
| 2025-05-13 | 110.16x |
| 2025-05-12 | 104.26x |
| 2025-05-09 | 89.37x |
| 2025-05-08 | 118.16x |
| 2025-05-07 | 115.84x |
| 2025-05-06 | 112.03x |
| 2025-05-05 | 115.84x |
| 2025-05-02 | 119.19x |
| 2025-05-01 | 115.56x |
| 2025-04-30 | 116.21x |
| 2025-04-29 | 117.70x |
| 2025-04-28 | 116.03x |
| 2025-04-25 | 115.29x |
| 2025-04-24 | 114.82x |
| 2025-04-23 | 112.13x |
| 2025-04-22 | 113.15x |
| 2025-04-21 | 111.57x |
| 2025-04-17 | 111.48x |
| 2025-04-16 | 106.37x |
| 2025-04-15 | 108.69x |
| 2025-04-14 | 110.27x |
| 2025-04-11 | 107.95x |
| 2025-04-10 | 107.58x |
| 2025-04-09 | 110.92x |
| 2025-04-08 | 103.30x |
| 2025-04-07 | 110.55x |
| 2025-04-04 | 111.38x |
| 2025-04-03 | 117.70x |
| 2025-04-02 | 121.04x |
| 2025-04-01 | 120.86x |
| 2025-03-31 | 120.86x |
| 2025-03-28 | 121.60x |
| 2025-03-27 | 125.22x |
| 2025-03-26 | 122.07x |
| 2025-03-25 | 124.48x |
| 2025-03-24 | 125.13x |
| 2025-03-21 | 124.48x |
| 2025-03-20 | 126.34x |
| 2025-03-19 | 129.40x |
| 2025-03-18 | 128.57x |
| 2025-03-17 | 130.89x |
| 2022-08-04 | 21.41x |
| 2022-08-03 | 23.48x |
| 2022-08-02 | 22.82x |
| 2022-08-01 | 22.19x |
| 2022-07-29 | 21.92x |
| 2022-07-28 | 22.28x |
| 2022-07-27 | 22.49x |
| 2022-07-26 | 21.63x |
| 2022-07-25 | 20.89x |
| 2022-07-22 | 20.77x |
| 2022-07-21 | 21.06x |
| 2022-07-20 | 20.99x |
| 2022-07-19 | 21.33x |
| 2022-07-18 | 20.55x |
| 2022-07-15 | 21.71x |
| 2022-07-14 | 21.10x |
| 2022-07-13 | 21.32x |
| 2022-07-12 | 21.03x |
| 2022-07-11 | 20.83x |
| 2022-07-08 | 21.10x |
| 2022-07-07 | 20.96x |
| 2022-07-06 | 20.90x |
| 2022-07-05 | 21.20x |
| 2022-07-01 | 20.92x |
| 2022-06-30 | 20.69x |
| 2022-06-29 | 20.92x |
| 2022-06-28 | 20.54x |
| 2022-06-27 | 21.48x |
| 2022-06-24 | 20.94x |
| 2022-06-23 | 22.09x |
| 2022-06-22 | 21.00x |
| 2022-06-21 | 20.77x |
| 2022-06-17 | 20.41x |
| 2022-06-16 | 20.31x |
| 2022-06-15 | 20.26x |
| 2022-06-14 | 18.51x |
| 2022-06-13 | 18.49x |
| 2022-06-10 | 19.15x |
| 2022-06-09 | 20.24x |
| 2022-06-08 | 20.31x |
| 2022-06-07 | 20.36x |
Showing the most recent 260 of 4,034 data points. The chart above shows the full history.