AC Immune S.A. (ACIU) vs Anika Therapeutics, Inc. (ANIK)

A side-by-side comparison of AC Immune S.A. and Anika Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — ACIU vs ANIK

growth of $100 · dividends reinvested · last 10y
ACIU -83.1% (-16.3%/yr)ANIK -57.8% (-8.3%/yr)ANIK compounded faster over this window
050100150Start $10020182020202220242026$17$42
ACIU ANIK

ACIU vs ANIK: by the numbers

  • •ACIU is the larger company ($273M vs $264M market cap).
  • •Both run net losses; ANIK's is the smaller (-3.14% vs -249.94% net margin).
  • •Both shrank revenue over the past five years; ANIK's decline was smaller (-2.48% vs -23.70% CAGR).

Metrics side by side

Valuation

MetricACIUANIK
Forward P/EN/A18.79
P/S ratio12.572.19
P/B ratio6.271.92
EV / EBITDAN/A489.09
FCF yieldN/A0.21%

Profitability

MetricACIUANIK
Gross margin100.00%62.16%
Operating margin-1927.32%-4.24%
Net margin-249.94%-3.14%
ROE-124.67%-2.76%
ROIC-89.43%-3.17%

Growth (annualized)

MetricACIUANIK
Revenue CAGR (5Y)-23.70%-2.48%
FCF CAGR (5Y)N/A-39.38%
Total return CAGR (5Y)-16.03%-13.40%

Frequently asked

Which has grown faster, ACIU or ANIK?
Neither grew: over the past five years both shrank revenue, with ANIK's decline the smaller — ACIU at a -23.70% CAGR versus ANIK at -2.48%.
How have ACIU and ANIK total returns compared?
Over the past 10 years, ACIU delivered -16.61% and ANIK delivered -8.51% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.