Is Merck & Co., Inc. (MRK) Fairly Valued?

Merck & Co., Inc. valuation review using P/E, fair value, revenue growth, EPS growth, net margin, and TGMCharts chart exhibits as of September 9, 2026.

By TGMCharts Research · Data as of · Updated

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Merck & Co., Inc. trailing earnings multiple of 118.08x sits alongside an analyst DCF (FMP) reference of $182, indicating the current market price is below the independent intrinsic value estimate.

The core evidence is the relationship between price, earnings, fair value, and business support. Five-year revenue CAGR is 7.87%, five-year EPS CAGR is 21.21%, and net margin is 4.78%. Those facts decide whether the multiple is defensible or stretched.

  • Merck & Co., Inc. closed at $148 on September 9, 2026.
  • Trailing P/E is 118.08x and price-to-sales is 5.49x.
  • Analyst DCF (FMP) is $182 with margin of safety at 23.64%.
  • Five-year revenue CAGR is 7.87% and five-year EPS CAGR is 21.21%.
  • Earnings yield is 0.85% and net margin is 4.78%.

Valuation Setup

The market price, model anchor, growth support, and profitability facts behind the valuation read.

Latest close
$148
Trailing P/E
118.08x
Price to sales
5.49x
Analyst DCF (FMP)
$182
Margin of safety
23.64%
5Y EPS CAGR
21.21%

Market Price Versus Long-Term Fundamentals

The investment profile of Merck & Co., Inc. presents a notable disconnect between high trailing earnings multiples and long-term valuation models. At the market close on September 9, 2026, the stock was priced at $148, which translates to a trailing price-to-earnings ratio of 118.08x. This elevated multiple is contrasted by an analyst-DCF (FMP) fair value estimate of $182, implying a margin of safety of 23.64%.

Assessing this setup requires looking beyond a single metric. The relationship between the market's willingness to pay and the underlying business performance is clarified by analyzing price-to-sales, earnings yield, and historical growth. When these metrics align, they provide a coherent framework for evaluating the stock's current market position.

Current compounder snapshot · MRK

Live supporting context; not part of the article's frozen 2026-09-09 evidence snapshot.

Score
21/100
10Y CAGR
5.1%
Median YoY
5.2%
YoY volatility
σ 11.3pp· uneven
Quarters ≥ 20%
4 of 40
Negative quarters
8
Valuation vs own 10Y history
P/S 5.5x · 10Y median 4.3x · 98th percentile · as of Sep 9, 2026
How this score is computed
  • Quarters at or above 20%: 4 of 40 4 of 40 pts
  • Steadiness (typical swing 11.3pp) → 16.9 of 25 pts
  • Pace (median 5.2% YoY) → 0 of 20 pts
  • Latest quarter (5.1% YoY) → 0 of 15 pts
  • Score: 21 of 100

Annualized revenue (TTM) · by quarter, last 40

$0.00$20.00B$40.00B$60.00B$80.00B20172019202120232025

Quarterly YoY revenue growth vs the 20% line

-40%-20%0%20%40%60%20%20172019202120232025

P/S multiple vs its 10Y median

3x3.5x4x4.5x5x5.5x6x10Y median 4.3x20172019202120232025

MRK compounder charts →All consistent compounders →

Evaluating Current Market Multiples

To understand what the market is paying for the business, we must examine the broader multiple context. The stock trades at a price-to-sales ratio of 5.49x, while the trailing earnings yield stands at 0.85%. This low earnings yield highlights how much future cash flow expansion is already incorporated into the current market price.

P/E ratio

MRK P/E ratio Chart

118.08x

The trailing earnings multiple is the main valuation exhibit because it connects the market price to reported earnings. Historical series through 2026-09-09.

+251.95% over 5Y

Latest P/E ratio: 118.08x as of September 9, 2026.

A P/E ratio of 118.08x has to be judged against the company's five-year EPS CAGR of 21.21%. If the multiple is high while EPS support is ordinary, the valuation thesis becomes more dependent on investor confidence than on fresh earnings power.

price-to-sales

MRK price-to-sales Chart

5.49x

Price-to-sales gives a second valuation lens when margins and earnings can move around the cycle. Historical series through 2026-09-09.

+33.25% over 5Y

Latest price-to-sales ratio: 5.49x.

Price-to-sales at 5.49x is most useful beside net margin of 4.78%. A richer sales multiple is easier to defend when margin quality is durable rather than temporarily elevated.

Discount to Third-Party Intrinsic Value Estimates

The market price of $148 sits below the third-party analyst DCF (FMP) reference of $182. This gap represents a margin of safety of 23.64%, suggesting that longer-term structural models project higher value than what is currently reflected in daily trading. However, this independent reference should be weighed alongside the company's operational trends rather than viewed as a definitive pricing target.

The valuation at a glance

Each input on its own line: what the stock costs against earnings and sales, the model's fair value and how far price sits from it, and the growth and margins behind the business.

Price-to-earnings (P/E)

Value
118.08x

Earnings yield

Value
0.85%

Analyst DCF (FMP)

Value
$182

Margin of safety vs analyst DCF (FMP)

Value
23.64%

Revenue growth, five-year

Value
7.87%

EPS growth, five-year

Value
21.21%

Net profit margin

Value
4.78%

Price-to-sales (P/S)

Value
5.49x
earnings yield

MRK earnings yield Chart

0.85%

Earnings yield reframes valuation from an owner's-yield perspective rather than a multiple perspective. Historical series through 2026-09-09.

-2.1pp over 5Y

Latest earnings yield: 0.85%.

The earnings yield of 0.85% is the counterweight to the P/E ratio. If the yield is thin relative to the quality and growth profile, the valuation case needs more help from future compounding.

Operational support for the stock's valuation shows a divergence between top-line expansion and bottom-line delivery. Over the last five years, revenue has expanded at a compound annual growth rate of 7.87%, demonstrating steady commercial demand. Conversely, the five-year EPS CAGR of 21.21% reflects longer-term per-share compounding, but recent trailing twelve-month net income and EPS growth have turned negative, signaling near-term pressure on profitability.

revenue

MRK revenue

$16.61B

Revenue history tests whether the valuation is being supported by real business expansion. Q2 FY2026 (2026-06-30): $16.61B.

+57.62% over 10Y

Five-year revenue CAGR: 7.87%. This is endpoint-to-endpoint across the five-year window — a depressed start year can inflate it, so read it against the recent bars.

Revenue growth is the business-expansion evidence behind the valuation read. A five-year revenue CAGR of 7.87% helps show how much of the valuation story is coming from company growth instead of only multiple expansion.

EPS

MRK EPS

$-0.54

EPS history checks whether reported earnings are keeping pace with the market multiple. Q2 FY2026 (2026-06-30): $-0.54.

-168.35% over 10Y

Five-year EPS CAGR: 21.21%. This is endpoint-to-endpoint across the five-year window — a depressed or negative start year can inflate it, so read it against the recent bars.

A five-year EPS CAGR of 21.21% is the clearest support figure for a P/E-based conclusion. If EPS growth slows while the multiple remains elevated, the article should become more cautious after refresh.

Profitability Margins and Sales Multiple Alignment

The sustainability of the current price-to-sales ratio of 5.49x depends heavily on the company's profitability profile. Currently, the net margin is 4.78%. When net margins face downward pressure, a high sales multiple becomes more difficult to sustain, as investors must rely on significant top-line acceleration to restore earnings power.

net margin

MRK net margin

-8.04%

Net margin shows whether the company has enough profitability quality to support its valuation. Q2 FY2026 (2026-06-30): -8.04%.

-28.8pp over 10Y

Net margin (TTM): 4.78%. The bars below are reported fiscal periods (quarterly where available).

Net margin of 4.78% is a quality signal, not a valuation verdict by itself. It matters because a premium multiple is more defensible when margins are structurally strong and less defensible when margins are peaking.

The Core Valuation Debate

The positive case for the stock rests on its long-term compounding record, characterized by a five-year revenue CAGR of 7.87% and a substantial five-year EPS CAGR of 21.21%, alongside the discount to the analyst-DCF (FMP) reference. The negative case centers on the demanding trailing P/E of 118.08x occurring at a time when recent net income and EPS growth have turned negative, leaving little room for further operational deceleration.

Bull and bear case

Valuation support

  • Five-year revenue CAGR of 7.87% and five-year EPS CAGR of 21.21% support the business case.
  • Net margin of 4.78% is the quality check behind the multiple.

Valuation pressure

  • A P/E ratio of 118.08x can become demanding if EPS growth slows.
  • The analyst-DCF (FMP) margin of safety at 23.64% should change the valuation read if it deteriorates after refresh.

Key Metrics to Monitor for a Shift in Outlook

Several factors could alter this valuation perspective. A continued contraction in trailing twelve-month net income would further stretch the P/E multiple, while a downward revision of the analyst-DCF (FMP) reference below $182 would reduce the current margin of safety. Additionally, any deviation from the five-year historical revenue growth trend of 7.87% would require a reassessment of the stock's long-term trajectory.

Synthesis of Valuation and Operational Support

In conclusion, Merck & Co., Inc. presents a complex valuation picture where a high trailing earnings multiple of 118.08x is counterbalanced by a discount to the independent fair value reference of $182. For the current valuation structure to hold, the business must stabilize its recent negative earnings growth and maintain its historical margin profile. This analysis is based on historical financial filings and does not constitute investment advice.

FAQ

Is MRK fairly valued?

Merck & Co., Inc. trades at 118.08x trailing earnings, while the price gap versus the third-party DCF (FMP) estimate is 23.64%. Read those references alongside five-year revenue CAGR of 7.87% and five-year EPS CAGR of 21.21%; none is a standalone verdict.

What valuation metric matters most for MRK?

This article anchors on P/E, fair value, margin of safety, price-to-sales, earnings yield, revenue growth, and EPS growth. No single metric is treated as a recommendation.

How often should this MRK valuation view refresh?

Numbers here are as of September 9, 2026 — the note's dated snapshot. A note whose figures can no longer be verified against the company's reported data is corrected or unpublished rather than left stale.

What would change our mind

  • A material move away from the analyst-DCF (FMP) reference of $182.
  • A break in five-year EPS support, currently 21.21%.
  • Margin quality drifting away from the latest net margin of 4.78%.

The bottom line

Merck & Co., Inc. valuation research note from TGMCharts Research, grounded in a dated fundamentals snapshot, chart exhibits, and linked source facts.

Read next: MRK fundamentalsContinue with Merck & Co., Inc.'s full stock page.
How we checked this researchShow

Data snapshot · By TGMCharts Research.

Every number in this note comes from data we compute and store ourselves from the company's reported figures, plus verbatim excerpts from its SEC filings. When a value isn't available we say so — we never fill gaps with estimates.

Latest filing excerpt

10-Q · filed 2026-08-07 · period 2026-06-30 · SEC EDGAR source

  • Combined global sales of Keytruda/Keytruda Qlex grew 5% and 8% in the second quarter and first six months of 2026, respectively.
  • Alliance revenue related to Lynparza grew 4% in the first six months of 2026 largely due to higher demand in the U.S.
  • Alliance - 34 - revenue related to this collaboration (consisting of royalties) increased 15% and 20% in the second quarter and first six months of 2026, respectively, primarily due to strong underlying sales performance.
  • Combined worldwide sales of Gardasil and Gardasil 9 declined 9% in the first six months of 2026 primarily driven by lower demand in China (discussed below) and in Japan, reflecting in part that the last date to initiate the first dose in Japan's national immunization program catch-up cohort was in March 2025.

Every number, checked

Full methodology