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VRTX
SPY

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Different business models: this comparison spans Healthcare, Financial Services. Margin, capital intensity, and valuation differences should be interpreted in that sector context.
Metric
ValuationTTM multiples, at last close
P/E Ratio32.18N/A
Forward P/E29.50N/A
P/B Ratio6.98N/A
P/S Ratio11.20N/A
P/FCF Ratio37.24N/A
EV/EBITDA26.95N/A
Profitabilitytrailing twelve months
Gross Margin86.0%N/A
Operating Margin38.6%N/A
Net Margin34.9%N/A
ROE21.8%N/A
ROA16.1%N/A
ROIC17.3%N/A
Financial Healthlatest reported quarter
Current Ratio3.19N/A
Quick Ratio2.74N/A
Debt/Equity0.10N/A
Interest Coverage357.95N/A
Dividendstrailing dividends vs latest price
Dividend YieldN/A1.0%
Payout RatioN/AN/A
Yrs of Dividend Growth05

N/A includes metrics that are structurally not meaningful for a company's sector (e.g. EV multiples, free-cash-flow ratios, and working-capital ratios for banks and insurers). Bars show each value's size relative to the row's largest — a factual magnitude cue, not a rating. Tap a metric name for its full history.