Which has grown faster, OPK or TNDM?

Over the past five years, TNDM grew revenue faster — OPK at a -21.00% CAGR versus TNDM at 11.48%.

How have OPK and TNDM total returns compared?

Over the past 10 years, OPK delivered -17.50% and TNDM delivered -14.43% annualized total return. Past performance doesn't predict future results.

OPKO Health, Inc. (OPK) vs Tandem Diabetes Care, Inc. (TNDM)

A side-by-side comparison of OPKO Health, Inc. and Tandem Diabetes Care, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

OPK

OPKO Health, Inc.

$1.10B

$1.48HealthcareDelayed quote: Oct 6, 2026, 2:20 PM EDT

TNDM

Tandem Diabetes Care, Inc.

$1.12B

$16.28HealthcareDelayed quote: Oct 6, 2026, 2:20 PM EDT

Total return — OPK vs TNDM

growth of $100 · dividends reinvested · last 10y

OPK -85.2% (-17.4%/yr)TNDM -78.8% (-14.4%/yr)TNDM compounded faster over this window

OPK TNDM

OPK vs TNDM: by the numbers

•TNDM is the larger company ($1.12B vs $1.10B market cap).
•Both run net losses; TNDM's is the smaller (-6.08% vs -12.40% net margin).
•TNDM grew revenue faster over the past five years (11.48% vs -21.00% CAGR).

Metrics side by side

Valuation

Metric	OPK	TNDM
P/S ratio	1.88	1.07
P/B ratio	0.93	8.56

Profitability

Metric	OPK	TNDM
Gross margin	21.10%	56.01%
Operating margin	-36.08%	-4.13%
Net margin	-12.40%	-6.08%
ROE	-6.16%	-48.56%
ROIC	-8.86%	-4.77%

Growth (annualized)

Metric	OPK	TNDM
Revenue CAGR (5Y)	-21.00%	11.48%
Total return CAGR (5Y)	-15.39%	-32.93%

Frequently asked

Which has grown faster, OPK or TNDM?: Over the past five years, TNDM grew revenue faster — OPK at a -21.00% CAGR versus TNDM at 11.48%.
How have OPK and TNDM total returns compared?: Over the past 10 years, OPK delivered -17.50% and TNDM delivered -14.43% annualized total return. Past performance doesn't predict future results.

Go deeper

Full OPK analysis Full TNDM analysis Interactive comparison tool

Dig into the metrics

OPKO Health ROE Tandem Diabetes Care ROE OPKO Health operating margin Tandem Diabetes Care operating margin OPKO Health revenue growth Tandem Diabetes Care revenue growth OPKO Health free cash flow Tandem Diabetes Care free cash flow

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.