MannKind Corporation (MNKD) vs OPKO Health, Inc. (OPK)
A side-by-side comparison of MannKind Corporation and OPKO Health, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
MNKD
MannKind Corporation
$3.82HealthcareDelayed quote: Oct 6, 2026, 11:55 AM EDT
OPK
OPKO Health, Inc.
$1.53HealthcareDelayed quote: Oct 6, 2026, 11:55 AM EDT
Total return — MNKD vs OPK
growth of $100 · dividends reinvested · last 10yMNKD +21.5% (+2.0%/yr)OPK -85.2% (-17.4%/yr)MNKD compounded faster over this window
Log scale — wide-divergence pair
MNKD OPK
MNKD vs OPK: by the numbers
- •MNKD is the larger company ($1.22B vs $1.14B market cap).
- •Both run net losses; MNKD's is the smaller (-11.08% vs -12.40% net margin).
- •MNKD grew revenue faster over the past five years (39.51% vs -21.00% CAGR).
Metrics side by side
Valuation
| Metric | MNKD | OPK |
|---|---|---|
| P/S ratio | 3.10 | 1.94 |
| P/B ratio | N/A | 0.97 |
| EV / EBITDA | 52.41 | N/A |
Profitability
| Metric | MNKD | OPK |
|---|---|---|
| Gross margin | 75.69% | 21.10% |
| Operating margin | 11.12% | -36.08% |
| Net margin | -11.08% | -12.40% |
| ROE | N/A | -6.16% |
| ROIC | 1.32% | -8.86% |
Growth (annualized)
| Metric | MNKD | OPK |
|---|---|---|
| Revenue CAGR (5Y) | 39.51% | -21.00% |
| Total return CAGR (5Y) | -4.18% | -15.39% |
Frequently asked
- Which has grown faster, MNKD or OPK?
- Over the past five years, MNKD grew revenue faster — MNKD at a 39.51% CAGR versus OPK at -21.00%.
- How have MNKD and OPK total returns compared?
- Over the past 10 years, MNKD delivered 1.97% and OPK delivered -17.50% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
MannKind ROEOPKO Health ROEMannKind operating marginOPKO Health operating marginMannKind revenue growthOPKO Health revenue growthMannKind free cash flowOPKO Health free cash flow
MannKind & OPKO Health appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.