Karyopharm Therapeutics Inc. (KPTI) vs Palatin Technologies, Inc. (PTN)

A side-by-side comparison of Karyopharm Therapeutics Inc. and Palatin Technologies, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

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Total return — KPTI vs PTN

growth of $100 · dividends reinvested · last 10y
KPTI -99.5% (-41.7%/yr)PTN -98.7% (-35.1%/yr)PTN compounded faster over this window
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KPTI PTN

KPTI vs PTN: by the numbers

  • •PTN is the larger company ($17M vs $15M market cap).
  • •Both run net losses; PTN's is the smaller (-63.54% vs -153.28% net margin).

Metrics side by side

Valuation

MetricKPTIPTN
P/S ratio0.101.27
P/B ratioN/A2.50

Profitability

MetricKPTIPTN
Gross margin95.88%99.63%
Operating margin-56.17%-65.74%
Net margin-153.28%-63.54%
ROEN/A-125.30%
ROICN/A-125.44%

Growth (annualized)

MetricKPTIPTN
Revenue CAGR (5Y)7.47%N/A
Total return CAGR (5Y)-62.18%-55.41%

Frequently asked

How have KPTI and PTN total returns compared?
Over the past 10 years, KPTI delivered -41.85% and PTN delivered -35.08% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.