Karyopharm Therapeutics Inc. (KPTI) vs Passage Bio, Inc. (PASG)
A side-by-side comparison of Karyopharm Therapeutics Inc. and Passage Bio, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
KPTI
Karyopharm Therapeutics Inc.
$0.68HealthcareDelayed quote: Oct 6, 2026, 2:15 PM EDT
PASG
Passage Bio, Inc.
$4.17HealthcareDelayed quote: Oct 6, 2026, 2:14 PM EDT
Total return — KPTI vs PASG
growth of $100 · dividends reinvested · last 7yKPTI -99.7% (-56.2%/yr)PASG -99.1% (-48.8%/yr)PASG compounded faster over this window
KPTI PASG
KPTI vs PASG: by the numbers
- •KPTI is the larger company ($15M vs $13M market cap).
- •Both run net losses; PASG's is the smaller (0.00% vs -153.28% net margin).
Metrics side by side
Valuation
| Metric | KPTI | PASG |
|---|---|---|
| P/S ratio | 0.11 | N/A |
| P/B ratio | N/A | 3.01 |
Profitability
| Metric | KPTI | PASG |
|---|---|---|
| Gross margin | 95.88% | 0.00% |
| Operating margin | -56.17% | 0.00% |
| Net margin | -153.28% | 0.00% |
| ROE | N/A | -810.41% |
| ROIC | N/A | -889.92% |
Growth (annualized)
| Metric | KPTI | PASG |
|---|---|---|
| Revenue CAGR (5Y) | 7.47% | N/A |
| Total return CAGR (5Y) | -62.18% | -53.23% |
Frequently asked
- How have KPTI and PASG total returns compared?
- Over the past 5 years, KPTI delivered -62.18% and PASG delivered -53.23% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.