Hologic, Inc. (HOLX) vs Moderna, Inc. (MRNA)

HOLX leads on 8 of 10 compared metrics.

A side-by-side comparison of Hologic, Inc. and Moderna, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 13, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

Total return — HOLX vs MRNA

growth of $100 · last 7y
HOLX +81.1%MRNA +169.4%MRNA compounded faster
05001k2k2k3kStart $1002020202220242026$181$269
HOLX MRNA

HOLX vs MRNA: by the numbers

  • MRNA is the larger company ($19.80B vs $16.97B market cap).
  • HOLX is profitable (13.18% net margin) while MRNA runs a net loss (-143.55%).
  • HOLX grew revenue faster over the past five years (-1.87% vs -2.60% CAGR).

Which is better, HOLX or MRNA?

Metric tally: HOLX 8 · MRNA 2

It depends on what you're optimizing for:

GrowthHOLX(faster 5Y revenue CAGR)
QualityHOLX(higher ROIC)

Valuation

MetricHOLXMRNA
P/E ratio31.67
Forward P/E17.21
P/S ratio4.168.86
P/B ratio3.272.66
EV / EBITDA17.28
FCF yield5.82%

Profitability

MetricHOLXMRNA
Gross margin52.82%-13.89%
Operating margin17.49%-153.35%
Net margin13.18%-143.55%
ROE10.37%-43.12%
ROIC7.35%-29.70%

Growth (annualized)

MetricHOLXMRNA
Revenue CAGR (5Y)-1.87%-2.60%
EPS CAGR (5Y)-0.96%
FCF CAGR (5Y)-4.57%126.92%
Total return CAGR (5Y)0.84%-25.58%

Frequently asked

Which is better, HOLX or MRNA?
It depends on your goal. growth: HOLX (faster 5Y revenue CAGR); quality: HOLX (higher ROIC). Across all compared metrics, HOLX leads 8 to 2.
Which has grown faster, HOLX or MRNA?
Over the past five years, HOLX grew revenue faster — HOLX at a -1.87% CAGR versus MRNA at -2.60%.
Is HOLX or MRNA more profitable?
HOLX runs the higher net margin — HOLX at 13.18% versus MRNA at -143.55%.
Which has been the better investment, HOLX or MRNA?
Over the past 5-year, HOLX delivered the higher annualized total return — HOLX at 7.99% versus MRNA at -25.58%. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 13, 2026.