Hologic, Inc. (HOLX) vs Moderna, Inc. (MRNA)
HOLX leads on 8 of 10 compared metrics.
A side-by-side comparison of Hologic, Inc. and Moderna, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 13, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).
Total return — HOLX vs MRNA
growth of $100 · last 7yHOLX +81.1%MRNA +169.4%MRNA compounded faster
HOLX MRNA
HOLX vs MRNA: by the numbers
- •MRNA is the larger company ($19.80B vs $16.97B market cap).
- •HOLX is profitable (13.18% net margin) while MRNA runs a net loss (-143.55%).
- •HOLX grew revenue faster over the past five years (-1.87% vs -2.60% CAGR).
Which is better, HOLX or MRNA?
Metric tally: HOLX 8 · MRNA 2It depends on what you're optimizing for:
GrowthHOLX(faster 5Y revenue CAGR)
QualityHOLX(higher ROIC)
Valuation
| Metric | HOLX | MRNA |
|---|---|---|
| P/E ratio | 31.67 | — |
| Forward P/E | 17.21 | — |
| P/S ratio | 4.16● | 8.86 |
| P/B ratio | 3.27 | 2.66● |
| EV / EBITDA | 17.28 | — |
| FCF yield | 5.82% | — |
Profitability
| Metric | HOLX | MRNA |
|---|---|---|
| Gross margin | 52.82%● | -13.89% |
| Operating margin | 17.49%● | -153.35% |
| Net margin | 13.18%● | -143.55% |
| ROE | 10.37%● | -43.12% |
| ROIC | 7.35%● | -29.70% |
Growth (annualized)
| Metric | HOLX | MRNA |
|---|---|---|
| Revenue CAGR (5Y) | -1.87%● | -2.60% |
| EPS CAGR (5Y) | -0.96% | — |
| FCF CAGR (5Y) | -4.57% | 126.92%● |
| Total return CAGR (5Y) | 0.84%● | -25.58% |
Frequently asked
- Which is better, HOLX or MRNA?
- It depends on your goal. growth: HOLX (faster 5Y revenue CAGR); quality: HOLX (higher ROIC). Across all compared metrics, HOLX leads 8 to 2.
- Which has grown faster, HOLX or MRNA?
- Over the past five years, HOLX grew revenue faster — HOLX at a -1.87% CAGR versus MRNA at -2.60%.
- Is HOLX or MRNA more profitable?
- HOLX runs the higher net margin — HOLX at 13.18% versus MRNA at -143.55%.
- Which has been the better investment, HOLX or MRNA?
- Over the past 5-year, HOLX delivered the higher annualized total return — HOLX at 7.99% versus MRNA at -25.58%. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Hologic P/E ratioModerna P/E ratioHologic dividend yieldModerna dividend yieldHologic ROEModerna ROEHologic operating marginModerna operating marginHologic revenue growthModerna revenue growthHologic free cash flowModerna free cash flow
Hologic & Moderna appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 13, 2026.