Fractyl Health, Inc. (GUTS) vs Talphera, Inc. (TLPH)

A side-by-side comparison of Fractyl Health, Inc. and Talphera, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — GUTS vs TLPH

growth of $100 · dividends reinvested · last 3y
GUTS -97.0% (-69.1%/yr)TLPH +23.4% (+7.3%/yr)TLPH compounded faster over this window
Log scale — wide-divergence pair
1101001kStart $10020252026$3$123
GUTS TLPH

GUTS vs TLPH: by the numbers

  • •GUTS is the larger company ($61M vs $57M market cap).
  • •Both run net losses; GUTS's is the smaller (0.00% vs -1507600.00% net margin).

Metrics side by side

Valuation

MetricGUTSTLPH
P/S ratioN/A57089.56
P/B ratioN/A3.96

Profitability

MetricGUTSTLPH
Gross margin0.00%100.00%
Operating margin0.00%-48157.14%
Net margin0.00%-1507600.00%
ROEN/A-104.65%
ROIC-129.67%-65.20%

Growth (annualized)

MetricGUTSTLPH
Revenue CAGR (5Y)N/A-79.92%
Total return CAGR (5Y)N/A-43.65%

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.