Which has grown faster, CRON or OPK?

Over the past five years, CRON grew revenue faster — CRON at a 31.80% CAGR versus OPK at -21.00%.

Is CRON or OPK more profitable?

CRON runs the higher net margin — CRON at 30.98% versus OPK at -12.40%.

How have CRON and OPK total returns compared?

Over the past 10 years, CRON delivered 13.62% and OPK delivered -17.50% annualized total return. Past performance doesn't predict future results.

Cronos Group Inc. (CRON) vs OPKO Health, Inc. (OPK)

A side-by-side comparison of Cronos Group Inc. and OPKO Health, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

CRON

Cronos Group Inc.

$1.23B

$3.29HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

OPK

OPKO Health, Inc.

$1.09B

$1.46HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — CRON vs OPK

growth of $100 · dividends reinvested · last 10y

CRON +258.4% (+13.6%/yr)OPK -85.2% (-17.4%/yr)CRON compounded faster over this window

Log scale — wide-divergence pair

CRON OPK

CRON vs OPK: by the numbers

•CRON is the larger company ($1.23B vs $1.09B market cap).
•CRON is profitable (30.98% net margin) while OPK runs a net loss (-12.40%).
•CRON grew revenue faster over the past five years (31.80% vs -21.00% CAGR).

Metrics side by side

Valuation

Metric	CRON	OPK
P/E ratio	18.14	N/A
P/S ratio	5.45	1.85
P/B ratio	1.15	0.92
EV / EBITDA	28.08	N/A
FCF yield	4.05%	N/A

Profitability

Metric	CRON	OPK
Gross margin	36.16%	21.10%
Operating margin	-11.96%	-36.08%
Net margin	30.98%	-12.40%
ROE	6.53%	-6.16%
ROIC	1.12%	-8.86%

Growth (annualized)

Metric	CRON	OPK
Revenue CAGR (5Y)	31.80%	-21.00%
Total return CAGR (5Y)	-9.92%	-15.39%

Frequently asked

Which has grown faster, CRON or OPK?: Over the past five years, CRON grew revenue faster — CRON at a 31.80% CAGR versus OPK at -21.00%.
Is CRON or OPK more profitable?: CRON runs the higher net margin — CRON at 30.98% versus OPK at -12.40%.
How have CRON and OPK total returns compared?: Over the past 10 years, CRON delivered 13.62% and OPK delivered -17.50% annualized total return. Past performance doesn't predict future results.

Go deeper

Full CRON analysis Full OPK analysis Interactive comparison tool

Dig into the metrics

Cronos P/E ratio Cronos ROE OPKO Health ROE Cronos operating margin OPKO Health operating margin Cronos revenue growth OPKO Health revenue growth Cronos free cash flow OPKO Health free cash flow

Cronos & OPKO Health appear in these rankings

Fastest Revenue Growth Stocks Highest FCF Yield Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.