Charles River Laboratories International, Inc. (CRL) vs Medpace Holdings, Inc. (MEDP)
A side-by-side comparison of Charles River Laboratories International, Inc. and Medpace Holdings, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 13, 2026. Differences are shown without an overall score or investment verdict.
CRL
Charles River Laboratories International, Inc.
$278.06HealthcareDelayed quote: Sep 18, 2026, 4:00 PM EDT
MEDP
Medpace Holdings, Inc.
$612.33HealthcareDelayed quote: Sep 18, 2026, 4:00 PM EDT
Total return — CRL vs MEDP
growth of $100 · dividends reinvested · last 10yCRL +229.6% (+12.7%/yr)MEDP +1874.9% (+34.8%/yr)MEDP compounded faster over this window
Log scale — wide-divergence pair
CRL MEDP
CRL vs MEDP: by the numbers
- •MEDP is the larger company ($17.09B vs $13.39B market cap).
- •MEDP is profitable (17.67% net margin) while CRL runs a net loss (-5.96%).
- •MEDP grew revenue faster over the past five years (22.03% vs 4.08% CAGR).
Metrics side by side
Valuation
| Metric | CRL | MEDP |
|---|---|---|
| P/E ratio | N/A | 35.87 |
| Forward P/E | 24.57 | 34.79 |
| P/S ratio | 3.35 | 6.14 |
| P/B ratio | 4.72 | 39.39 |
| EV / EBITDA | 20.50 | 27.34 |
| FCF yield | 2.77% | 4.10% |
Profitability
| Metric | CRL | MEDP |
|---|---|---|
| Gross margin | 32.24% | 28.76% |
| Operating margin | 12.35% | 20.97% |
| Net margin | -5.96% | 17.67% |
| ROE | -8.40% | 113.29% |
| ROIC | 7.72% | 77.00% |
Growth (annualized)
| Metric | CRL | MEDP |
|---|---|---|
| Revenue CAGR (5Y) | 4.08% | 22.03% |
| EPS CAGR (5Y) | -47.86% | 30.90% |
| FCF CAGR (5Y) | 6.43% | 23.40% |
| Total return CAGR (5Y) | -8.79% | 25.09% |
Frequently asked
- Which has grown faster, CRL or MEDP?
- Over the past five years, MEDP grew revenue faster — CRL at a 4.08% CAGR versus MEDP at 22.03%.
- Is CRL or MEDP more profitable?
- MEDP runs the higher net margin — CRL at -5.96% versus MEDP at 17.67%.
- How have CRL and MEDP total returns compared?
- Over the past 10 years, CRL delivered 13.45% and MEDP delivered 34.83% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Medpace P/E ratioCharles River Laboratories International ROEMedpace ROECharles River Laboratories International operating marginMedpace operating marginCharles River Laboratories International revenue growthMedpace revenue growthCharles River Laboratories International free cash flowMedpace free cash flow
Charles River Laboratories International & Medpace appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 13, 2026.