Which has grown faster, CRL or ICLR?

Over the past five years, ICLR grew revenue faster — CRL at a 4.08% CAGR versus ICLR at 20.93%.

Is CRL or ICLR more profitable?

ICLR runs the higher net margin — CRL at -5.96% versus ICLR at 3.99%.

How have CRL and ICLR total returns compared?

Over the past 10 years, CRL delivered 13.28% and ICLR delivered 7.67% annualized total return. Past performance doesn't predict future results.

Charles River Laboratories International, Inc. (CRL) vs ICON Public Limited Company (ICLR)

A side-by-side comparison of Charles River Laboratories International, Inc. and ICON Public Limited Company across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 3, 2026. Differences are shown without an overall score or investment verdict.

CRL

Charles River Laboratories International, Inc.

$13.98B

$290.19HealthcareDelayed quote: Oct 2, 2026, 4:00 PM EDT

ICLR

ICON Public Limited Company

$12.41B

$162.05HealthcareDelayed quote: Oct 2, 2026, 4:00 PM EDT

Total return — CRL vs ICLR

growth of $100 · dividends reinvested · last 10y

CRL +249.3% (+13.3%/yr)ICLR +112.9% (+7.8%/yr)CRL compounded faster over this window

CRL ICLR

CRL vs ICLR: by the numbers

•CRL is the larger company ($13.98B vs $12.41B market cap).
•ICLR is profitable (3.99% net margin) while CRL runs a net loss (-5.96%).
•ICLR grew revenue faster over the past five years (20.93% vs 4.08% CAGR).

Metrics side by side

Valuation

Metric	CRL	ICLR
P/E ratio	N/A	38.04
Forward P/E	25.57	15.30
P/S ratio	3.50	1.50
P/B ratio	4.92	1.32
EV / EBITDA	21.24	10.60
FCF yield	2.65%	10.85%

Profitability

Metric	CRL	ICLR
Gross margin	32.24%	21.85%
Operating margin	12.35%	10.15%
Net margin	-5.96%	3.99%
ROE	-8.40%	3.51%
ROIC	7.72%	4.80%

Growth (annualized)

Metric	CRL	ICLR
Revenue CAGR (5Y)	4.08%	20.93%
EPS CAGR (5Y)	N/A	-14.23%
FCF CAGR (5Y)	6.43%	22.10%
Total return CAGR (5Y)	-6.98%	-9.18%

Frequently asked

Which has grown faster, CRL or ICLR?: Over the past five years, ICLR grew revenue faster — CRL at a 4.08% CAGR versus ICLR at 20.93%.
Is CRL or ICLR more profitable?: ICLR runs the higher net margin — CRL at -5.96% versus ICLR at 3.99%.
How have CRL and ICLR total returns compared?: Over the past 10 years, CRL delivered 13.28% and ICLR delivered 7.67% annualized total return. Past performance doesn't predict future results.

Go deeper

Full CRL analysis Full ICLR analysis Interactive comparison tool

Dig into the metrics

ICON Public P/E ratio Charles River Laboratories International ROE ICON Public ROE Charles River Laboratories International operating margin ICON Public operating margin Charles River Laboratories International revenue growth ICON Public revenue growth Charles River Laboratories International free cash flow ICON Public free cash flow

Charles River Laboratories International & ICON Public appear in these rankings

Fastest Revenue Growth Stocks Highest FCF Yield Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 3, 2026.