Booking Holdings Inc. (BKNG) vs Regeneron Pharmaceuticals, Inc. (REGN)

A side-by-side comparison of Booking Holdings Inc. and Regeneron Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 10, 2026. Differences are shown without an overall score or investment verdict.

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Different business models: BKNG is classified in Consumer Cyclical; REGN is classified in Healthcare. Margin, capital intensity, and valuation differences should be interpreted in that sector context.

Total returnBKNG vs REGN

growth of $100 · dividends reinvested · last 10y
BKNG +218.8% (+12.3%/yr)REGN +108.5% (+7.6%/yr)BKNG compounded faster over this window
100200300400Start $10020182020202220242026$319$208
BKNG REGN

BKNG vs REGN: by the numbers

  • BKNG is the larger company ($134.77B vs $80.51B market cap).
  • REGN converts more revenue to profit (27.86% vs 25.53% net margin).
  • BKNG grew revenue faster over the past five years (31.52% vs 4.64% CAGR).
  • BKNG pays the higher dividend yield (0.92% vs 0.46%).

Metrics side by side

Valuation

MetricBKNGREGN
P/E ratio19.2919.33
Forward P/E16.6414.40
P/S ratio4.775.18
P/B ratioN/A2.54
EV / EBITDA13.3017.79
FCF yield7.08%4.37%

Profitability

MetricBKNGREGN
Gross margin100.00%84.86%
Operating margin34.49%25.56%
Net margin25.53%27.86%
ROEN/A13.65%
ROIC71.23%9.19%

Dividends

MetricBKNGREGN
Dividend yield0.92%0.46%
Payout ratio17.83%9.15%

Growth (annualized)

MetricBKNGREGN
Revenue CAGR (5Y)31.52%4.64%
EPS CAGR (5Y)158.62%5.70%
FCF CAGR (5Y)56.15%15.77%
Total return CAGR (5Y)14.07%4.76%

Frequently asked

Which has the lower trailing P/E, BKNG or REGN?
BKNG has the lower trailing P/E: BKNG trades at 19.29 and REGN at 19.33. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, BKNG or REGN?
Over the past five years, BKNG grew revenue faster — BKNG at a 31.52% CAGR versus REGN at 4.64%.
Does BKNG or REGN pay a bigger dividend?
BKNG yields 0.92% and REGN yields 0.46% based on trailing dividends and the latest price.
Is BKNG or REGN more profitable?
REGN runs the higher net margin — BKNG at 25.53% versus REGN at 27.86%.
How have BKNG and REGN total returns compared?
Over the past 10 years, BKNG delivered 12.15% and REGN delivered 7.81% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 10, 2026.