Which has grown faster, BIO or CRL?

Over the past five years, CRL grew revenue faster — BIO at a -0.84% CAGR versus CRL at 5.77%.

Is BIO or CRL more profitable?

BIO runs the higher net margin — BIO at 6.52% versus CRL at -4.59%.

Which has been the better investment, BIO or CRL?

Over the past 10-year, CRL delivered the higher annualized total return — BIO at 6.91% versus CRL at 8.26%. Past performance doesn't predict future results.

Bio-Rad Laboratories, Inc. (BIO) vs Charles River Laboratories International, Inc. (CRL)

BIO and CRL are evenly matched — 7 metrics each of 14.

A side-by-side comparison of Bio-Rad Laboratories, Inc. and Charles River Laboratories International, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 13, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

BIO

Bio-Rad Laboratories, Inc.

$7.73B

$285.94Healthcare

CRL

Charles River Laboratories International, Inc.

$9.03B

$187.51Healthcare

Not enough overlapping price history to compare BIO and CRL.

BIO vs CRL: by the numbers

•CRL is the larger company ($9.03B vs $7.73B market cap).
•BIO is profitable (6.52% net margin) while CRL runs a net loss (-4.59%).
•CRL grew revenue faster over the past five years (5.77% vs -0.84% CAGR).

Which is better, BIO or CRL?

Metric tally: BIO 7 · CRL 7

It depends on what you're optimizing for:

GrowthCRL(faster 5Y revenue CAGR)

QualityCRL(higher ROIC)

Valuation

Metric	BIO	CRL
P/E ratio	47.11	—
Forward P/E	28.69	15.21●
P/S ratio	2.98	2.28●
P/B ratio	1.13●	3.12
EV / EBITDA	20.01●	41.45
FCF yield	4.63%●	4.26%

Profitability

Metric	BIO	CRL
Gross margin	51.87%●	31.86%
Operating margin	9.25%	11.77%●
Net margin	6.52%●	-4.59%
ROE	2.46%●	-6.28%
ROIC	2.04%	8.36%●

Growth (annualized)

Metric	BIO	CRL
Revenue CAGR (5Y)	-0.84%	5.77%●
EPS CAGR (5Y)	-26.27%●	-40.99%
FCF CAGR (5Y)	-7.57%	-3.98%●
Total return CAGR (5Y)	-13.82%	-11.83%●

Frequently asked

Which is better, BIO or CRL?: It depends on your goal. growth: CRL (faster 5Y revenue CAGR); quality: CRL (higher ROIC). Across all compared metrics, they are evenly matched.
Which has grown faster, BIO or CRL?: Over the past five years, CRL grew revenue faster — BIO at a -0.84% CAGR versus CRL at 5.77%.
Is BIO or CRL more profitable?: BIO runs the higher net margin — BIO at 6.52% versus CRL at -4.59%.
Which has been the better investment, BIO or CRL?: Over the past 10-year, CRL delivered the higher annualized total return — BIO at 6.91% versus CRL at 8.26%. Past performance doesn't predict future results.

Go deeper

Full BIO analysis Full CRL analysis Interactive comparison tool

Dig into the metrics

Bio-Rad Laboratories P/E ratio Charles River Laboratories International P/E ratio Bio-Rad Laboratories dividend yield Charles River Laboratories International dividend yield Bio-Rad Laboratories ROE Charles River Laboratories International ROE Bio-Rad Laboratories operating margin Charles River Laboratories International operating margin Bio-Rad Laboratories revenue growth Charles River Laboratories International revenue growth Bio-Rad Laboratories free cash flow Charles River Laboratories International free cash flow

Bio-Rad Laboratories & Charles River Laboratories International appear in these rankings

Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 13, 2026.