Bio-Rad Laboratories, Inc. (BIO) vs Charles River Laboratories International, Inc. (CRL)
A side-by-side comparison of Bio-Rad Laboratories, Inc. and Charles River Laboratories International, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of July 29, 2026. Differences are shown without an overall score or investment verdict.
BIO
Bio-Rad Laboratories, Inc.
$327.25HealthcareDelayed quote: Jul 29, 2026, 4:00 PM EDT
CRL
Charles River Laboratories International, Inc.
$234.80HealthcareDelayed quote: Jul 29, 2026, 4:00 PM EDT
Total return — BIO vs CRL
growth of $100 · dividends reinvested · last 26yBIO +2717.0%CRL +992.9%BIO compounded faster
BIO CRL
BIO vs CRL: by the numbers
- •CRL is the larger company ($11.31B vs $8.85B market cap).
- •BIO is profitable (6.52% net margin) while CRL runs a net loss (-4.59%).
- •CRL grew revenue faster over the past five years (5.77% vs 0.29% CAGR).
Metrics side by side
Valuation
| Metric | BIO | CRL |
|---|---|---|
| P/E ratio | 54.53 | N/A |
| Forward P/E | 36.61 | 21.65 |
| P/S ratio | 3.45 | 2.92 |
| P/B ratio | 1.30 | 4.00 |
| EV / EBITDA | 22.38 | 17.76 |
| FCF yield | 4.00% | 3.32% |
Profitability
| Metric | BIO | CRL |
|---|---|---|
| Gross margin | 51.87% | 31.86% |
| Operating margin | 9.25% | 11.77% |
| Net margin | 6.52% | -4.59% |
| ROE | 2.46% | -6.28% |
| ROIC | 2.04% | 8.36% |
Growth (annualized)
| Metric | BIO | CRL |
|---|---|---|
| Revenue CAGR (5Y) | 0.29% | 5.77% |
| EPS CAGR (5Y) | -26.27% | -40.99% |
| FCF CAGR (5Y) | -7.57% | 6.43% |
| Total return CAGR (5Y) | -14.06% | -9.66% |
Frequently asked
- Which has grown faster, BIO or CRL?
- Over the past five years, CRL grew revenue faster — BIO at a 0.29% CAGR versus CRL at 5.77%.
- Is BIO or CRL more profitable?
- BIO runs the higher net margin — BIO at 6.52% versus CRL at -4.59%.
- How have BIO and CRL total returns compared?
- Over the past 10 years, BIO delivered 8.64% and CRL delivered 10.64% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Bio-Rad Laboratories P/E ratioCharles River Laboratories International P/E ratioBio-Rad Laboratories dividend yieldCharles River Laboratories International dividend yieldBio-Rad Laboratories ROECharles River Laboratories International ROEBio-Rad Laboratories operating marginCharles River Laboratories International operating marginBio-Rad Laboratories revenue growthCharles River Laboratories International revenue growthBio-Rad Laboratories free cash flowCharles River Laboratories International free cash flow
Bio-Rad Laboratories & Charles River Laboratories International appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified July 29, 2026.