Which has grown faster, ASND or CRL?

Over the past five years, ASND grew revenue faster — ASND at a 189.92% CAGR versus CRL at 4.08%.

Is ASND or CRL more profitable?

ASND runs the higher net margin — ASND at 71.08% versus CRL at -5.96%.

How have ASND and CRL total returns compared?

Over the past 10 years, ASND delivered 27.41% and CRL delivered 14.12% annualized total return. Past performance doesn't predict future results.

Ascendis Pharma A/S (ASND) vs Charles River Laboratories International, Inc. (CRL)

A side-by-side comparison of Ascendis Pharma A/S and Charles River Laboratories International, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

ASND

Ascendis Pharma A/S

$14.16B

$228.03HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT

CRL

Charles River Laboratories International, Inc.

$14.97B

$310.77HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT

Total return — ASND vs CRL

growth of $100 · dividends reinvested · last 10y

ASND +1027.2% (+27.4%/yr)CRL +274.1% (+14.1%/yr)ASND compounded faster over this window

ASND CRL

ASND vs CRL: by the numbers

•CRL is the larger company ($14.97B vs $14.16B market cap).
•ASND is profitable (71.08% net margin) while CRL runs a net loss (-5.96%).
•ASND grew revenue faster over the past five years (189.92% vs 4.08% CAGR).

Metrics side by side

Valuation

Metric	ASND	CRL
P/E ratio	17.33	N/A
Forward P/E	N/A	27.39
P/S ratio	11.59	3.74
P/B ratio	8.64	5.27
EV / EBITDA	93.79	22.49
FCF yield	2.73%	2.48%

Profitability

Metric	ASND	CRL
Gross margin	90.18%	32.24%
Operating margin	-18.92%	12.35%
Net margin	71.08%	-5.96%
ROE	52.97%	-8.40%
ROIC	5.85%	7.72%

Growth (annualized)

Metric	ASND	CRL
Revenue CAGR (5Y)	189.92%	4.08%
FCF CAGR (5Y)	N/A	6.43%
Total return CAGR (5Y)	7.40%	-4.99%

Frequently asked

Which has grown faster, ASND or CRL?: Over the past five years, ASND grew revenue faster — ASND at a 189.92% CAGR versus CRL at 4.08%.
Is ASND or CRL more profitable?: ASND runs the higher net margin — ASND at 71.08% versus CRL at -5.96%.
How have ASND and CRL total returns compared?: Over the past 10 years, ASND delivered 27.41% and CRL delivered 14.12% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ASND analysis Full CRL analysis Interactive comparison tool

Dig into the metrics

Ascendis Pharma A/S P/E ratio Ascendis Pharma A/S ROE Charles River Laboratories International ROE Ascendis Pharma A/S operating margin Charles River Laboratories International operating margin Ascendis Pharma A/S revenue growth Charles River Laboratories International revenue growth Ascendis Pharma A/S free cash flow Charles River Laboratories International free cash flow

Ascendis Pharma A/S & Charles River Laboratories International appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.