Align Technology, Inc. (ALGN) vs Charles River Laboratories International, Inc. (CRL)
A side-by-side comparison of Align Technology, Inc. and Charles River Laboratories International, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of July 28, 2026. Differences are shown without an overall score or investment verdict.
ALGN
Align Technology, Inc.
$175.60HealthcareDelayed quote: Jul 28, 2026, 4:00 PM EDT
CRL
Charles River Laboratories International, Inc.
$240.43HealthcareDelayed quote: Jul 28, 2026, 4:00 PM EDT
Total return — ALGN vs CRL
growth of $100 · dividends reinvested · last 25yALGN +926.7%CRL +871.4%ALGN compounded faster
ALGN CRL
ALGN vs CRL: by the numbers
- •ALGN is the larger company ($12.58B vs $11.58B market cap).
- •ALGN is profitable (10.50% net margin) while CRL runs a net loss (-4.59%).
- •ALGN grew revenue faster over the past five years (7.78% vs 5.77% CAGR).
Metrics side by side
Valuation
| Metric | ALGN | CRL |
|---|---|---|
| P/E ratio | 28.20 | N/A |
| Forward P/E | 14.78 | 20.20 |
| P/S ratio | 2.94 | 2.73 |
| P/B ratio | 2.90 | 3.73 |
| PEG ratio | 51.77 | N/A |
| EV / EBITDA | 13.10 | 16.80 |
| FCF yield | 5.70% | 3.56% |
Profitability
| Metric | ALGN | CRL |
|---|---|---|
| Gross margin | 67.68% | 31.86% |
| Operating margin | 14.44% | 11.77% |
| Net margin | 10.50% | -4.59% |
| ROE | 10.36% | -6.28% |
| ROIC | 9.94% | 8.36% |
Growth (annualized)
| Metric | ALGN | CRL |
|---|---|---|
| Revenue CAGR (5Y) | 7.78% | 5.77% |
| EPS CAGR (5Y) | -24.16% | -40.99% |
| FCF CAGR (5Y) | -1.16% | 6.43% |
| Total return CAGR (5Y) | -22.56% | -9.80% |
Frequently asked
- Which has grown faster, ALGN or CRL?
- Over the past five years, ALGN grew revenue faster — ALGN at a 7.78% CAGR versus CRL at 5.77%.
- Is ALGN or CRL more profitable?
- ALGN runs the higher net margin — ALGN at 10.50% versus CRL at -4.59%.
- How have ALGN and CRL total returns compared?
- Over the past 10 years, ALGN delivered 7.35% and CRL delivered 10.55% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Align Technology P/E ratioCharles River Laboratories International P/E ratioAlign Technology dividend yieldCharles River Laboratories International dividend yieldAlign Technology ROECharles River Laboratories International ROEAlign Technology operating marginCharles River Laboratories International operating marginAlign Technology revenue growthCharles River Laboratories International revenue growthAlign Technology free cash flowCharles River Laboratories International free cash flow
Align Technology & Charles River Laboratories International appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified July 28, 2026.