Alector, Inc. (ALEC) vs MacroGenics, Inc. (MGNX)
A side-by-side comparison of Alector, Inc. and MacroGenics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ALEC
Alector, Inc.
$1.90HealthcareDelayed quote: Oct 6, 2026, 1:00 PM EDT
MGNX
MacroGenics, Inc.
$3.66HealthcareDelayed quote: Oct 6, 2026, 12:55 PM EDT
Total return — ALEC vs MGNX
growth of $100 · dividends reinvested · last 8yALEC -88.9% (-24.1%/yr)MGNX -83.5% (-20.2%/yr)MGNX compounded faster over this window
ALEC MGNX
ALEC vs MGNX: by the numbers
- •MGNX is the larger company ($233M vs $211M market cap).
- •Both run net losses; MGNX's is the smaller (-8.70% vs -850.13% net margin).
- •MGNX grew revenue faster over the past five years (7.33% vs -8.35% CAGR).
Metrics side by side
Valuation
| Metric | ALEC | MGNX |
|---|---|---|
| P/S ratio | 15.26 | 1.39 |
| P/B ratio | N/A | 5.43 |
Profitability
| Metric | ALEC | MGNX |
|---|---|---|
| Gross margin | 54.09% | 71.12% |
| Operating margin | -692.83% | -48.72% |
| Net margin | -850.13% | -8.70% |
| ROE | N/A | -34.04% |
| ROIC | -71.04% | -16.87% |
Growth (annualized)
| Metric | ALEC | MGNX |
|---|---|---|
| Revenue CAGR (5Y) | -8.35% | 7.33% |
| Total return CAGR (5Y) | -39.17% | -28.42% |
Frequently asked
- Which has grown faster, ALEC or MGNX?
- Over the past five years, MGNX grew revenue faster — ALEC at a -8.35% CAGR versus MGNX at 7.33%.
- How have ALEC and MGNX total returns compared?
- Over the past 5 years, ALEC delivered -39.17% and MGNX delivered -28.42% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.