Which has grown faster, AGIO or VIR?

Over the past five years, VIR grew revenue faster — AGIO at a 4.54% CAGR versus VIR at 11.22%.

How have AGIO and VIR total returns compared?

Over the past 5 years, AGIO delivered -6.59% and VIR delivered -19.71% annualized total return. Past performance doesn't predict future results.

Agios Pharmaceuticals, Inc. (AGIO) vs Vir Biotechnology, Inc. (VIR)

A side-by-side comparison of Agios Pharmaceuticals, Inc. and Vir Biotechnology, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

AGIO

Agios Pharmaceuticals, Inc.

$1.89B

$31.72HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

VIR

Vir Biotechnology, Inc.

$1.96B

$11.60HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — AGIO vs VIR

growth of $100 · dividends reinvested · last 7y

AGIO -0.8% (-0.1%/yr)VIR -16.0% (-2.5%/yr)AGIO compounded faster over this window

AGIO VIR

AGIO vs VIR: by the numbers

•VIR is the larger company ($1.96B vs $1.89B market cap).
•Both run net losses; VIR's is the smaller (-83.00% vs -418.24% net margin).
•VIR grew revenue faster over the past five years (11.22% vs 4.54% CAGR).

Metrics side by side

Valuation

Metric	AGIO	VIR
P/S ratio	19.26	6.45
P/B ratio	1.85	1.99

Profitability

Metric	AGIO	VIR
Gross margin	78.67%	82.92%
Operating margin	-873.87%	-682.68%
Net margin	-418.24%	-83.00%
ROE	-40.09%	-25.62%
ROIC	-44.21%	-24.09%

Growth (annualized)

Metric	AGIO	VIR
Revenue CAGR (5Y)	4.54%	11.22%
Total return CAGR (5Y)	-6.59%	-19.71%

Frequently asked

Which has grown faster, AGIO or VIR?: Over the past five years, VIR grew revenue faster — AGIO at a 4.54% CAGR versus VIR at 11.22%.
How have AGIO and VIR total returns compared?: Over the past 5 years, AGIO delivered -6.59% and VIR delivered -19.71% annualized total return. Past performance doesn't predict future results.

Go deeper

Full AGIO analysis Full VIR analysis Interactive comparison tool

Dig into the metrics

Agios Pharmaceuticals ROE Vir Biotechnology ROE Agios Pharmaceuticals operating margin Vir Biotechnology operating margin Agios Pharmaceuticals revenue growth Vir Biotechnology revenue growth Agios Pharmaceuticals free cash flow Vir Biotechnology free cash flow

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.