Agios Pharmaceuticals, Inc. (AGIO) vs Novavax, Inc. (NVAX)
A side-by-side comparison of Agios Pharmaceuticals, Inc. and Novavax, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
AGIO
Agios Pharmaceuticals, Inc.
$31.71HealthcareDelayed quote: Oct 6, 2026, 11:50 AM EDT
NVAX
Novavax, Inc.
$11.44HealthcareDelayed quote: Oct 6, 2026, 11:50 AM EDT
Total return — AGIO vs NVAX
growth of $100 · dividends reinvested · last 10yAGIO -41.9% (-5.3%/yr)NVAX -68.6% (-10.9%/yr)AGIO compounded faster over this window
AGIO NVAX
AGIO vs NVAX: by the numbers
- •AGIO is the larger company ($1.89B vs $1.88B market cap).
- •Both run net losses; NVAX's is the smaller (-59.87% vs -418.24% net margin).
- •NVAX grew revenue faster over the past five years (118.86% vs 4.54% CAGR).
Metrics side by side
Valuation
| Metric | AGIO | NVAX |
|---|---|---|
| P/S ratio | 19.25 | 4.55 |
| P/B ratio | 1.85 | N/A |
Profitability
| Metric | AGIO | NVAX |
|---|---|---|
| Gross margin | 78.67% | 93.67% |
| Operating margin | -873.87% | 50.14% |
| Net margin | -418.24% | -59.87% |
| ROE | -40.09% | N/A |
| ROIC | -44.21% | -36.37% |
Growth (annualized)
| Metric | AGIO | NVAX |
|---|---|---|
| Revenue CAGR (5Y) | 4.54% | 118.86% |
| Total return CAGR (5Y) | -6.59% | -40.61% |
Frequently asked
- Which has grown faster, AGIO or NVAX?
- Over the past five years, NVAX grew revenue faster — AGIO at a 4.54% CAGR versus NVAX at 118.86%.
- How have AGIO and NVAX total returns compared?
- Over the past 10 years, AGIO delivered -5.39% and NVAX delivered -10.98% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Agios Pharmaceuticals ROENovavax ROEAgios Pharmaceuticals operating marginNovavax operating marginAgios Pharmaceuticals revenue growthNovavax revenue growthAgios Pharmaceuticals free cash flowNovavax free cash flow
Agios Pharmaceuticals & Novavax appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.