Basis: Trailing twelve months (TTM net income over TTM revenue). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the net profit margin high or low?
The net profit margin of -147.38% is 100% above its 5-year average of -30732.11%, near the high end of its 5-year range (-182935.71%–11.27%).
85.14% above its 12-month average of -991.64%.
Reported quarterly profit margin; no daily interpolation. Q2 FY2026 (2026-06-30): -4591.76%.
NET PROFIT MARGIN
-147.38%
NET PROFIT MARGIN AVG TTM
-991.64%
NET PROFIT MARGIN AVG 3Y
-2309.81%
NET PROFIT MARGIN AVG 5Y
-30732.11%
NET PROFIT MARGIN AVG 10Y
-1670.03%
NET PROFIT MARGIN AVG 15Y
-3716.87%
NET PROFIT MARGIN AVG 20Y
-2954.89%
CURRENT VS TTM AVG
+85.14%
CURRENT VS 3Y AVG
+93.62%
CURRENT VS 5Y AVG
+99.52%
CURRENT VS 10Y AVG
+91.18%
CURRENT VS 15Y AVG
+96.03%
CURRENT VS 20Y AVG
+95.01%
SECTOR MEDIAN · HEALTHCARE
0.00%
median of 706 covered companies
CURRENT VS SECTOR MEDIAN
N/A
vs the sector median at left
Lexicon Pharmaceuticals, Inc.
Market Cap
$784.23M
Net Profit Margin
-147.38%
TTM Avg
-991.64%
3Y Avg
-2309.81%
5Y Avg
-30732.11%
Market Cap
$789.07M
Net Profit Margin
-34.17%
TTM Avg
-136.69%
3Y Avg
-25443.25%
5Y Avg
-23332.75%
Market Cap
$778.76M
Net Profit Margin
-4490.89%
TTM Avg
-2245.45%
3Y Avg
-2245.45%
5Y Avg
-2245.45%
Market Cap
$795.92M
Net Profit Margin
-7.58%
TTM Avg
0.29%
3Y Avg
-4.57%
5Y Avg
-4.54%
Market Cap
$778.67M
Net Profit Margin
1.92%
TTM Avg
0.94%
3Y Avg
-28.83%
5Y Avg
-18.64%
Market Cap
$798.82M
Net Profit Margin
-14.52%
TTM Avg
7.87%
3Y Avg
-15.98%
5Y Avg
-254.57%
Market Cap
$804.44M
Net Profit Margin
20.69%
TTM Avg
35.62%
3Y Avg
36.75%
5Y Avg
38.26%
Market Cap
$764.79M
Net Profit Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
| NAME | MARKET CAP | NET PROFIT MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Lexicon Pharmaceuticals, Inc. (LXRX) | $784.23M | -147.38% | -991.64% | -2309.81% | -30732.11% |
| Geron Corporation (GERN)vs › | $789.07M | -34.17% | -136.69% | -25443.25% | -23332.75% |
| Attovia Therapeutics, Inc. (ATTO)vs › | $778.76M | -4490.89% | -2245.45% | -2245.45% | -2245.45% |
| AdaptHealth Corp. (AHCO)vs › | $795.92M | -7.58% | 0.29% | -4.57% | -4.54% |
| Mesa Laboratories, Inc. (MLAB)vs › | $778.67M | 1.92% | 0.94% | -28.83% | -18.64% |
| Gyre Therapeutics, Inc. (GYRE)vs › | $798.82M | -14.52% | 7.87% | -15.98% | -254.57% |
| Apnimed, Inc. (APMD)vs › | $802.84M | N/A | N/A | N/A | N/A |
| InMode Ltd. (INMD)vs › | $804.44M | 20.69% | 35.62% | 36.75% | 38.26% |
| Design Therapeutics, Inc. (DSGN)vs › | $764.79M | 0.00% | 0.00% | 0.00% | 0.00% |
| Faeth Therapeutics, Inc. (FTH)vs › | $752.35M | 0.00% | 0.00% | 0.00% | 0.00% |
Operating Margin
-98.2%
Net Profit Margin
-147.4%
Net Profit Margin = Net Income / Revenue
Net profit margin is the percentage of revenue that becomes net income after all expenses, taxes, and interest.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | NET PROFIT MARGIN |
|---|---|
| 2026-06-30 | -4591.76% |
| 2026-03-31 | -4.94% |
| 2025-12-31 | -282.72% |
| 2025-09-30 | -90.04% |
| 2025-06-30 | 11.27% |
| 2025-03-31 | -2004.36% |
| 2024-12-31 | -127.16% |
| 2024-09-30 | -3703.49% |
| 2024-06-30 | -3244.02% |
| 2024-03-31 | -4282.92% |
| 2023-12-31 | -7087.75% |
| 2023-09-30 | -31188.27% |
| 2023-06-30 | -14165.30% |
| 2023-03-31 | -133058.33% |
| 2022-12-31 | -108907.14% |
| 2022-09-30 | -59966.67% |
| 2022-06-30 | -70248.57% |
| 2022-03-31 | -63448.65% |
| 2021-12-31 | -182935.71% |
| 2021-09-30 | -100530.43% |
| 2021-06-30 | -7720.94% |
| 2021-03-31 | -77622.22% |
| 2020-12-31 | -2761.31% |
| 2020-09-30 | 1245.15% |
| 2020-06-30 | -753.80% |
| 2020-03-31 | -832.74% |
| 2019-12-31 | -585.97% |
| 2019-09-30 | 76.78% |
| 2019-06-30 | -237.74% |
| 2019-03-31 | -236.51% |
| 2018-12-31 | -98.30% |
| 2018-09-30 | -401.28% |
| 2018-06-30 | -252.35% |
| 2018-03-31 | -166.92% |
| 2017-12-31 | -85.87% |
| 2017-09-30 | -114.03% |
| 2017-06-30 | -290.87% |
| 2017-03-31 | -190.73% |
| 2016-12-31 | -140.73% |
| 2016-09-30 | -129.94% |
| 2016-06-30 | -189.72% |
| 2016-03-31 | -279.20% |
| 2015-12-31 | 68.16% |
| 2015-09-30 | -6233.57% |
| 2015-06-30 | -7466.49% |
| 2015-03-31 | -1566.74% |
| 2014-12-31 | -13.65% |
| 2014-09-30 | -9665.39% |
| 2014-06-30 | -3850.30% |
| 2014-03-31 | -11131.77% |
| 2013-12-31 | -1235.04% |
| 2013-09-30 | -13301.68% |
| 2013-06-30 | -13588.79% |
| 2013-03-31 | -7215.00% |
| 2012-12-31 | -11409.63% |
| 2012-09-30 | -7940.59% |
| 2012-06-30 | -13030.65% |
| 2012-03-31 | -9956.00% |
| 2011-12-31 | -9867.35% |
| 2011-09-30 | -7352.96% |
| 2011-06-30 | -4799.64% |
| 2011-03-31 | -4971.31% |
| 2010-12-31 | -1835.51% |
| 2010-09-30 | -3522.79% |
| 2010-06-30 | -2043.23% |
| 2010-03-31 | -1588.67% |
| 2009-12-31 | -1558.43% |
| 2009-09-30 | -898.26% |
| 2009-06-30 | -787.62% |
| 2009-03-31 | -517.27% |
| 2008-12-31 | -242.79% |
| 2008-09-30 | -312.29% |
| 2008-06-30 | -209.43% |
| 2008-03-31 | -257.21% |
| 2007-12-31 | -88.19% |
| 2007-09-30 | -138.79% |
| 2007-06-30 | -107.46% |
| 2007-03-31 | -140.16% |
| 2006-12-31 | -86.04% |
| 2006-09-30 | -65.03% |
| 2006-06-30 | -104.57% |
| 2006-03-31 | -51.69% |
| 2005-12-31 | 17.45% |
| 2005-09-30 | -101.13% |
| 2005-06-30 | -106.79% |
| 2005-03-31 | -95.27% |
| 2004-12-31 | -2.08% |
| 2004-09-30 | -109.67% |
| 2004-06-30 | -155.76% |
| 2004-03-31 | -130.60% |
| 2003-12-31 | -108.58% |
| 2003-09-30 | -120.20% |
| 2003-06-30 | -197.50% |
| 2003-03-31 | -211.51% |
| 2002-12-31 | -136.98% |
| 2002-09-30 | -209.77% |
