Basis: Trailing twelve months (TTM net income over TTM revenue). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the net profit margin high or low?
The net profit margin of -34.06% is 84% below its 5-year average of -18.54%, near the high end of its 5-year range (-759.45%–75.70%).
45.96% above its 12-month average of -63.03%.
Reported quarterly profit margin; no daily interpolation. Q2 FY2026 (2026-06-30): -34.09%.
NET PROFIT MARGIN
-34.06%
NET PROFIT MARGIN AVG TTM
-63.03%
NET PROFIT MARGIN AVG 3Y
-210.59%
NET PROFIT MARGIN AVG 5Y
-18.54%
NET PROFIT MARGIN AVG 10Y
N/A
NET PROFIT MARGIN AVG 15Y
N/A
NET PROFIT MARGIN AVG 20Y
N/A
CURRENT VS TTM AVG
+45.96%
CURRENT VS 3Y AVG
+83.83%
CURRENT VS 5Y AVG
-83.73%
CURRENT VS 10Y AVG
N/A
CURRENT VS 15Y AVG
N/A
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
-0.35%
median of 862 covered companies
CURRENT VS SECTOR MEDIAN
-9631.43%
vs the sector median at left
Xilio Therapeutics, Inc.
Market Cap
$59.18M
Net Profit Margin
-34.06%
TTM Avg
-63.03%
3Y Avg
-210.59%
5Y Avg
-18.54%
Market Cap
$58.44M
Net Profit Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
Market Cap
$58.43M
Net Profit Margin
0.00%
TTM Avg
0.00%
3Y Avg
-69.82%
5Y Avg
-186.89%
Market Cap
$60.02M
Net Profit Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
Market Cap
$58.29M
Net Profit Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
Market Cap
$58.06M
Net Profit Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
Market Cap
$60.42M
Net Profit Margin
0.00%
TTM Avg
-36932.26%
3Y Avg
-34526.76%
5Y Avg
-23017.84%
Market Cap
$57.76M
Net Profit Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
Market Cap
$57.61M
Net Profit Margin
-1507600.00%
TTM Avg
-25517.85%
3Y Avg
-13465.42%
5Y Avg
-10648.78%
| NAME | MARKET CAP | NET PROFIT MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Xilio Therapeutics, Inc. (XLO) | $59.18M | -34.06% | -63.03% | -210.59% | -18.54% |
| PDS Biotechnology Corporation (PDSB)vs › | $58.44M | 0.00% | 0.00% | 0.00% | 0.00% |
| Adicet Bio, Inc. (ACET)vs › | $58.43M | 0.00% | 0.00% | -69.82% | -186.89% |
| Oncolytics Biotech Inc. (ONCY)vs › | $60.02M | 0.00% | 0.00% | 0.00% | 0.00% |
| MiNK Therapeutics, Inc. (INKT)vs › | $58.29M | 0.00% | 0.00% | 0.00% | 0.00% |
| Kalaris Therapeutics Inc (KLRS)vs › | $58.06M | 0.00% | 0.00% | 0.00% | 0.00% |
| Fractyl Health, Inc. (GUTS)vs › | $60.42M | 0.00% | -36932.26% | -34526.76% | -23017.84% |
| Boundless Bio, Inc. (BOLD)vs › | $57.76M | 0.00% | 0.00% | 0.00% | 0.00% |
| Talphera, Inc. (TLPH)vs › | $57.61M | -1507600.00% | -25517.85% | -13465.42% | -10648.78% |
| Connect Biopharma Holdings Limited (CNTB)vs › | $57.01M | -86687.50% | -43373.76% | -21686.88% | -14457.92% |
Operating Margin
-95.9%
Net Profit Margin
-34.1%
Net Profit Margin = Net Income / Revenue
Net profit margin is the percentage of revenue that becomes net income after all expenses, taxes, and interest.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | NET PROFIT MARGIN |
|---|---|
| 2026-06-30 | -34.09% |
| 2026-03-31 | -75.34% |
| 2025-12-31 | 75.70% |
| 2025-09-30 | -85.42% |
| 2025-06-30 | -195.99% |
| 2025-03-31 | -452.73% |
| 2024-12-31 | -759.45% |
| 2024-09-30 | -619.53% |
| 2024-06-30 | -590.79% |
| 2024-03-31 | 0.00% |
| 2023-12-31 | 0.00% |
| 2023-09-30 | 0.00% |
| 2023-06-30 | 0.00% |
| 2023-03-31 | 0.00% |
| 2022-12-31 | 0.00% |
| 2022-09-30 | 0.00% |
| 2022-06-30 | 0.00% |
| 2022-03-31 | 0.00% |
| 2021-12-31 | 0.00% |
| 2021-09-30 | 0.00% |
| 2021-06-30 | 0.00% |
| 2021-03-31 | 0.00% |
| 2020-12-31 | 0.00% |
| 2020-09-30 | 0.00% |
| 2020-06-30 | 0.00% |
| 2020-03-31 | 0.00% |