Basis: Trailing twelve months (TTM net income over TTM revenue). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the net profit margin high or low?
The net profit margin of -87.60% is 39% below its 5-year average of -62.86%, near the high end of its 5-year range (-6044.85%–76.00%).
21.02% above its 12-month average of -110.91%.
Reported quarterly profit margin; no daily interpolation. Q2 FY2026 (2026-06-30): -67.82%.
NET PROFIT MARGIN
-87.60%
NET PROFIT MARGIN AVG TTM
-110.91%
NET PROFIT MARGIN AVG 3Y
-150.08%
NET PROFIT MARGIN AVG 5Y
-62.86%
NET PROFIT MARGIN AVG 10Y
-2397.75%
NET PROFIT MARGIN AVG 15Y
N/A
NET PROFIT MARGIN AVG 20Y
N/A
CURRENT VS TTM AVG
+21.02%
CURRENT VS 3Y AVG
+41.63%
CURRENT VS 5Y AVG
-39.35%
CURRENT VS 10Y AVG
+96.35%
CURRENT VS 15Y AVG
N/A
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
-0.26%
median of 863 covered companies
CURRENT VS SECTOR MEDIAN
-33592.31%
vs the sector median at left
Syndax Pharmaceuticals, Inc.
Market Cap
$1.54B
Net Profit Margin
-87.60%
TTM Avg
-110.91%
3Y Avg
-150.08%
5Y Avg
-62.86%
Market Cap
$1.54B
Net Profit Margin
80.56%
TTM Avg
35.15%
3Y Avg
48.19%
5Y Avg
54.54%
Market Cap
$1.57B
Net Profit Margin
-753.60%
TTM Avg
-123.57%
3Y Avg
-563.59%
5Y Avg
-375.72%
Market Cap
$1.50B
Net Profit Margin
21.25%
TTM Avg
9.48%
3Y Avg
-48.31%
5Y Avg
-19.09%
Market Cap
$1.50B
Net Profit Margin
12.02%
TTM Avg
-7.78%
3Y Avg
-15.24%
5Y Avg
-11964.64%
Market Cap
$1.59B
Net Profit Margin
-140.43%
TTM Avg
-164.31%
3Y Avg
-442.76%
5Y Avg
-354.21%
Market Cap
$1.49B
Net Profit Margin
-685.80%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
Market Cap
$1.48B
Net Profit Margin
6.57%
TTM Avg
5.15%
3Y Avg
3.47%
5Y Avg
4.27%
Market Cap
$1.60B
Net Profit Margin
-1350.73%
TTM Avg
-1059.67%
3Y Avg
-1046.38%
5Y Avg
-742.65%
| NAME | MARKET CAP | NET PROFIT MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Syndax Pharmaceuticals, Inc. (SNDX) | $1.54B | -87.60% | -110.91% | -150.08% | -62.86% |
| Innoviva, Inc. (INVA)vs › | $1.54B | 80.56% | 35.15% | 48.19% | 54.54% |
| Stoke Therapeutics, Inc. (STOK)vs › | $1.57B | -753.60% | -123.57% | -563.59% | -375.72% |
| Nutex Health, Inc. (NUTX)vs › | $1.50B | 21.25% | 9.48% | -48.31% | -19.09% |
| Eton Pharmaceuticals, Inc. (ETON)vs › | $1.50B | 12.02% | -7.78% | -15.24% | -11964.64% |
| Kestra Medical Technologies, Ltd. (KMTS)vs › | $1.59B | -140.43% | -164.31% | -442.76% | -354.21% |
| Rapport Therapeutics, Inc. Common Stock (RAPP)vs › | $1.49B | -685.80% | 0.00% | 0.00% | 0.00% |
| Phibro Animal Health Corporation (PAHC)vs › | $1.48B | 6.57% | 5.15% | 3.47% | 4.27% |
| uniQure N.V. (QURE)vs › | $1.60B | -1350.73% | -1059.67% | -1046.38% | -742.65% |
| GH Research PLC (GHRS)vs › | $1.48B | 0.00% | 0.00% | 0.00% | 0.00% |
Operating Margin
-158.4%
Net Profit Margin
-87.6%
Net Profit Margin = Net Income / Revenue
Net profit margin is the percentage of revenue that becomes net income after all expenses, taxes, and interest.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | NET PROFIT MARGIN |
|---|---|
| 2026-06-30 | -67.82% |
| 2026-03-31 | -65.79% |
| 2025-12-31 | -99.32% |
| 2025-09-30 | -132.36% |
| 2025-06-30 | -189.28% |
| 2025-03-31 | -423.34% |
| 2024-12-31 | -1226.16% |
| 2024-09-30 | -673.01% |
| 2024-06-30 | -1944.66% |
| 2024-03-31 | 0.00% |
| 2023-12-31 | 0.00% |
| 2023-09-30 | 0.00% |
| 2023-06-30 | 0.00% |
| 2023-03-31 | 0.00% |
| 2022-12-31 | 0.00% |
| 2022-09-30 | 0.00% |
| 2022-06-30 | 0.00% |
| 2022-03-31 | 0.00% |
| 2021-12-31 | 76.00% |
| 2021-09-30 | -166.78% |
| 2021-06-30 | -6044.85% |
| 2021-03-31 | -7314.78% |
| 2020-12-31 | -5374.47% |
| 2020-09-30 | -5392.35% |
| 2020-06-30 | -4501.85% |
| 2020-03-31 | -4020.05% |
| 2019-12-31 | -3684.21% |
| 2019-09-30 | -3384.96% |
| 2019-06-30 | -3935.62% |
| 2019-03-31 | -3773.61% |
| 2018-12-31 | -4957.11% |
| 2018-09-30 | -4574.67% |
| 2018-06-30 | -4851.72% |
| 2018-03-31 | -5118.21% |
| 2017-12-31 | -1601.34% |
| 2017-09-30 | -4946.89% |
| 2017-06-30 | -4471.80% |
| 2017-03-31 | -4252.79% |
| 2016-12-31 | -3545.90% |
| 2016-09-30 | -4907.87% |
| 2016-06-30 | -2740.33% |
| 2016-03-31 | -3386.89% |
| 2015-12-31 | -1725.57% |
| 2015-09-30 | -2534.75% |
| 2015-06-30 | -36552.94% |
| 2015-03-31 | 0.00% |
| 2014-12-31 | 0.00% |
| 2014-09-30 | -647.67% |
| 2014-06-30 | 0.00% |
| 2014-03-31 | 0.00% |
| 2013-12-31 | 0.00% |
| 2013-09-30 | 0.00% |
| 2013-06-30 | 0.00% |
| 2013-03-31 | 0.00% |
| 2012-12-31 | 0.00% |
