Basis: Latest reported fiscal year. Source: stored company filings and market data; unavailable inputs remain N/A.
Is the return on invested capital (ROIC) high or low?
The return on invested capital (ROIC) of -94.79% is 35% below its 1-year average of -70.21%, near the low end of its 1-year range (-94.79%–-45.63%).
As of the fiscal period ended Wednesday, December 31, 2025. 35.01% below its 12-month average of -70.21%.
Limited history available
GENB Return on Invested Capital (ROIC) has fewer than three reported periods, so a trend chart would be misleading.
RETURN ON INVESTED CAPITAL (ROIC)
-94.79%
RETURN ON INVESTED CAPITAL (ROIC) AVG TTM
-70.21%
RETURN ON INVESTED CAPITAL (ROIC) AVG 3Y
N/A
RETURN ON INVESTED CAPITAL (ROIC) AVG 5Y
N/A
RETURN ON INVESTED CAPITAL (ROIC) AVG 10Y
N/A
RETURN ON INVESTED CAPITAL (ROIC) AVG 15Y
N/A
RETURN ON INVESTED CAPITAL (ROIC) AVG 20Y
N/A
CURRENT VS TTM AVG
-35.01%
CURRENT VS 3Y AVG
N/A
CURRENT VS 5Y AVG
N/A
CURRENT VS 10Y AVG
N/A
CURRENT VS 15Y AVG
N/A
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
-33.39%
median of 664 covered companies
CURRENT VS SECTOR MEDIAN
-183.93%
vs the sector median at left
Generate Biomedicines, Inc.
Market Cap
$1.79B
Return on Invested Capital (ROIC)
-94.79%
TTM Avg
-70.21%
3Y Avg
N/A
5Y Avg
N/A
Market Cap
$1.82B
Return on Invested Capital (ROIC)
9.81%
TTM Avg
8.38%
3Y Avg
8.16%
5Y Avg
8.82%
Market Cap
$1.83B
Return on Invested Capital (ROIC)
-26.88%
TTM Avg
-21.15%
3Y Avg
-18.76%
5Y Avg
-12.71%
Market Cap
$1.84B
Return on Invested Capital (ROIC)
4.13%
TTM Avg
4.21%
3Y Avg
5.71%
5Y Avg
5.17%
Market Cap
$1.73B
Return on Invested Capital (ROIC)
-54.45%
TTM Avg
-54.60%
3Y Avg
-46.39%
5Y Avg
-38.46%
Market Cap
$1.84B
Return on Invested Capital (ROIC)
-52.66%
TTM Avg
-61.09%
3Y Avg
-54.75%
5Y Avg
-42.45%
Market Cap
$1.86B
Return on Invested Capital (ROIC)
-23.90%
TTM Avg
-49.28%
3Y Avg
-183.01%
5Y Avg
-156.37%
Market Cap
$1.73B
Return on Invested Capital (ROIC)
9.23%
TTM Avg
-10.32%
3Y Avg
-22.84%
5Y Avg
-22.10%
Market Cap
$1.72B
Return on Invested Capital (ROIC)
10.03%
TTM Avg
-6.49%
3Y Avg
-7.14%
5Y Avg
-3.83%
| NAME | MARKET CAP | RETURN ON INVESTED CAPITAL (ROIC) | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Generate Biomedicines, Inc. (GENB) | $1.79B | -94.79% | -70.21% | N/A | N/A |
| LeMaitre Vascular, Inc. (LMAT)vs › | $1.82B | 9.81% | 8.38% | 8.16% | 8.82% |
| Novocure Ltd (NVCR)vs › | $1.83B | -26.88% | -21.15% | -18.76% | -12.71% |
| Astrana Health, Inc. (ASTH)vs › | $1.84B | 4.13% | 4.21% | 5.71% | 5.17% |
| Intellia Therapeutics, Inc. (NTLA)vs › | $1.73B | -54.45% | -54.60% | -46.39% | -38.46% |
| Absci Corporation (ABSI)vs › | $1.84B | -52.66% | -61.09% | -54.75% | -42.45% |
| Palvella Therapeutics, Inc. (PVLA)vs › | $1.86B | -23.90% | -49.28% | -183.01% | -156.37% |
| Alignment Healthcare, Inc. (ALHC)vs › | $1.73B | 9.23% | -10.32% | -22.84% | -22.10% |
| DENTSPLY SIRONA Inc. (XRAY)vs › | $1.72B | 10.03% | -6.49% | -7.14% | -3.83% |
| Personalis, Inc. (PSNL)vs › | $1.71B | -42.87% | -29.07% | -38.98% | -32.39% |
ROIC
-94.8%
ROE
N/A
ROIC = NOPAT / Invested Capital, where NOPAT = Operating Income × (1 − effective tax rate) and Invested Capital = Total Assets − (Current Liabilities − Short-Term Debt)
Return on invested capital measures the after-tax operating return a company earns on the capital invested in the business. TGMCharts computes it from reported statements: trailing-twelve-month operating income after tax, over invested capital at the latest balance sheet — total assets less the non-interest-bearing current liabilities (payables, accruals, deferred revenue) that fund them; short-term debt stays in the capital base. The tax rate is the period's own effective rate (income tax ÷ pretax income), capped at 45%; when pretax income is zero or negative, or the tax line is a net benefit, no tax is deducted — the operating figure is shown untaxed rather than adjusted by an assumed rate. Not shown for banks, insurers or funds.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | RETURN ON INVESTED CAPITAL (ROIC) |
|---|---|
| 2025-12-31 | -94.79% |
| 2024-12-31 | -45.63% |
